ENSG00000227471


Homo sapiens

Features
Gene ID: ENSG00000227471
  
Biological name :AKR1B15
  
Synonyms : AKR1B15 / aldo-keto reductase family 1 member B15 / C9JRZ8
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: 1
Band: q33
Gene start: 134549136
Gene end: 134579875
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSP00000389289
Ensembl peptide - ENSP00000397009
NCBI entrez gene - 441282     See in Manteia.
OMIM - 616336
RefSeq - NM_001080538
RefSeq - XM_011516241
RefSeq - XM_017012224
RefSeq Peptide - NP_001074007
swissprot - C9JRZ8
Ensembl - ENSG00000227471
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 akr1b1ENSDARG00000006215Danio rerio
 si:dkey-180p18.9ENSDARG00000045598Danio rerio
 Akr1b10ENSMUSG00000061758Mus musculus
 Akr1b7ENSMUSG00000052131Mus musculus
 Akr1b8ENSMUSG00000029762Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
O60218 / AKR1B10 / aldo-keto reductase family 1 member B10ENSG0000019807479
AKR1B1 / P15121 / aldo-keto reductase family 1 member BENSG0000008566259
AKR1E2 / Q96JD6 / aldo-keto reductase family 1 member E2ENSG0000016556851
AKR1D1 / P51857 / aldo-keto reductase family 1 member D1ENSG0000012278744
AKR1A1 / P14550 / aldo-keto reductase family 1 member A1ENSG0000011744842
AKR1C4 / P17516 / aldo-keto reductase family 1 member C4ENSG0000019861042
AKR1C2 / P52895 / aldo-keto reductase family 1 member C2ENSG0000015163242
AKR1C1 / Q04828 / aldo-keto reductase family 1 member C1ENSG0000018713442
AKR1C3 / P42330 / aldo-keto reductase family 1 member C3ENSG0000019613941


Protein motifs (from Interpro)
Interpro ID Name
 IPR018170  Aldo/keto reductase, conserved site
 IPR020471  Aldo/keto reductase
 IPR023210  NADP-dependent oxidoreductase domain
 IPR036812  NADP-dependent oxidoreductase domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006703 estrogen biosynthetic process TAS
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005759 mitochondrial matrix TAS
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0004303 estradiol 17-beta-dehydrogenase activity TAS
 molecular_functionGO:0016491 oxidoreductase activity IEA


Pathways (from Reactome)
Pathway description
Estrogen biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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