ENSG00000173662


Homo sapiens

Features
Gene ID: ENSG00000173662
  
Biological name :TAS1R1
  
Synonyms : Q7RTX1 / TAS1R1 / taste 1 receptor member 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: p36.31
Gene start: 6555181
Gene end: 6579757
  
Corresponding Affymetrix probe sets: 1555417_a_at (Human Genome U133 Plus 2.0 Array)   1564883_a_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000312558
Ensembl peptide - ENSP00000331867
Ensembl peptide - ENSP00000408448
Ensembl peptide - ENSP00000414166
NCBI entrez gene - 80835     See in Manteia.
OMIM - 606225
RefSeq - XM_017002403
RefSeq - NM_138697
RefSeq - NM_177540
RefSeq - XM_011542203
RefSeq - XM_011542206
RefSeq - XM_017002402
RefSeq Peptide - NP_619642
RefSeq Peptide - NP_803884
swissprot - H7C3W7
swissprot - Q7RTX1
swissprot - H0Y6X0
Ensembl - ENSG00000173662
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tas1r1ENSDARG00000056739Danio rerio
 TAS1R1ENSGALG00000046030Gallus gallus
 Tas1r1ENSMUSG00000028950Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8TE23 / TAS1R2 / taste 1 receptor member 2ENSG0000017900236
Q7RTX0 / TAS1R3 / taste 1 receptor member 3ENSG0000016996231
GPRC6A / Q5T6X5 / G protein-coupled receptor class C group 6 member AENSG0000017361228
GRM4 / Q14833 / glutamate metabotropic receptor 4ENSG0000012449325
GRM5 / P41594 / glutamate metabotropic receptor 5ENSG0000016895925
GRM1 / Q13255 / glutamate metabotropic receptor 1ENSG0000015282225
GRM6 / O15303 / glutamate metabotropic receptor 6ENSG0000011326224
GRM2 / Q14416 / glutamate metabotropic receptor 2ENSG0000016408224
GRM7 / Q14831 / glutamate metabotropic receptor 7ENSG0000019627723
GRM8 / O00222 / glutamate metabotropic receptor 8ENSG0000017960323
GRM3 / Q14832 / glutamate metabotropic receptor 3ENSG0000019882223


Protein motifs (from Interpro)
Interpro ID Name
 IPR000337  GPCR, family 3
 IPR001828  Receptor, ligand binding region
 IPR011500  GPCR, family 3, nine cysteines domain
 IPR017978  GPCR family 3, C-terminal
 IPR017979  GPCR, family 3, conserved site
 IPR028082  Periplasmic binding protein-like I


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0050896 response to stimulus IEA
 biological_processGO:0050909 sensory perception of taste IEA
 biological_processGO:0050917 sensory perception of umami taste IDA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0008527 taste receptor activity IDA
 molecular_functionGO:0046982 protein heterodimerization activity NAS


Pathways (from Reactome)
Pathway description
G alpha (i) signalling events
Class C/3 (Metabotropic glutamate/pheromone receptors)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000169962 Q7RTX0 / TAS1R3 / taste 1 receptor member 3  / complex






 

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