ENSG00000179002


Homo sapiens

Features
Gene ID: ENSG00000179002
  
Biological name :TAS1R2
  
Synonyms : Q8TE23 / TAS1R2 / taste 1 receptor member 2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p36.13
Gene start: 18839599
Gene end: 18859682
  
Corresponding Affymetrix probe sets: 1553529_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000364520
NCBI entrez gene - 80834     See in Manteia.
OMIM - 606226
RefSeq - NM_152232
RefSeq Peptide - NP_689418
swissprot - Q8TE23
Ensembl - ENSG00000179002
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q925I4ENSMUSG00000028738Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q7RTX1 / TAS1R1 / taste 1 receptor member 1ENSG0000017366236
Q7RTX0 / TAS1R3 / taste 1 receptor member 3ENSG0000016996229
GPRC6A / Q5T6X5 / G protein-coupled receptor class C group 6 member AENSG0000017361228
GRM2 / Q14416 / glutamate metabotropic receptor 2ENSG0000016408225
GRM5 / P41594 / glutamate metabotropic receptor 5ENSG0000016895924
GRM6 / O15303 / glutamate metabotropic receptor 6ENSG0000011326224
GRM1 / Q13255 / glutamate metabotropic receptor 1ENSG0000015282223
GRM7 / Q14831 / glutamate metabotropic receptor 7ENSG0000019627723
GRM4 / Q14833 / glutamate metabotropic receptor 4ENSG0000012449323
GRM3 / Q14832 / glutamate metabotropic receptor 3ENSG0000019882223
GRM8 / O00222 / glutamate metabotropic receptor 8ENSG0000017960322


Protein motifs (from Interpro)
Interpro ID Name
 IPR000337  GPCR, family 3
 IPR001828  Receptor, ligand binding region
 IPR011500  GPCR, family 3, nine cysteines domain
 IPR017978  GPCR family 3, C-terminal
 IPR017979  GPCR, family 3, conserved site
 IPR028082  Periplasmic binding protein-like I


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001582 detection of chemical stimulus involved in sensory perception of sweet taste IDA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IC
 biological_processGO:0032467 positive regulation of cytokinesis IMP
 biological_processGO:0050896 response to stimulus IEA
 biological_processGO:0050909 sensory perception of taste IEA
 biological_processGO:0050916 sensory perception of sweet taste IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IC
 cellular_componentGO:0043235 receptor complex IDA
 cellular_componentGO:1903767 sweet taste receptor complex IDA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0008527 taste receptor activity IDA
 molecular_functionGO:0033041 sweet taste receptor activity IDA
 molecular_functionGO:0046982 protein heterodimerization activity NAS


Pathways (from Reactome)
Pathway description
G alpha (i) signalling events
Class C/3 (Metabotropic glutamate/pheromone receptors)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000169962 Q7RTX0 / TAS1R3 / taste 1 receptor member 3  / complex






 

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