ENSMUSG00000028738


Mus musculus

Features
Gene ID: ENSMUSG00000028738
  
Biological name :Tas1r2
  
Synonyms : Q925I4 / Tas1r2 / taste receptor, type 1, member 2
  
Possible biological names infered from orthology : Q8TE23 / taste 1 receptor member 2
  
Species: Mus musculus
  
Chr. number: 4
Strand: 1
Band: D3
Gene start: 139653538
Gene end: 139670280
  
Corresponding Affymetrix probe sets: 10509811 (MoGene1.0st)   1450313_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000127737
Ensembl peptide - ENSMUSP00000030510
NCBI entrez gene - 83770     See in Manteia.
MGI - MGI:1933546
RefSeq - NM_031873
RefSeq Peptide - NP_114079
swissprot - E9Q0R6
swissprot - Q925I4
Ensembl - ENSMUSG00000028738
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q8TE23ENSG00000179002Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Tas1r1 / taste receptor, type 1, member 1 / Q7RTX1* / taste 1 receptor member 1*ENSMUSG0000002895037
Gprc6a / Q8K4Z6 / G protein-coupled receptor, family C, group 6, member A / Q5T6X5* / G protein-coupled receptor class C group 6 member A*ENSMUSG0000001990529
Q925D8 / Tas1r3 / Taste receptor type 1 member 3 / Q7RTX0* / taste 1 receptor member 3*ENSMUSG0000002907229
Grm6 / Q5NCH9 / Metabotropic glutamate receptor 6 / O15303* / glutamate metabotropic receptor 6*ENSMUSG0000000061725
Grm4 / glutamate receptor, metabotropic 4 / Q14833* / glutamate metabotropic receptor 4*ENSMUSG0000006323924
Grm7 / Q68ED2 / Metabotropic glutamate receptor 7 / Q14831* / glutamate metabotropic receptor 7*ENSMUSG0000005675524
Grm2 / Q14BI2 / Metabotropic glutamate receptor 2 / Q14416* / glutamate metabotropic receptor 2*ENSMUSG0000002319223
Grm3 / Q9QYS2 / Metabotropic glutamate receptor 3 / Q14832* / glutamate metabotropic receptor 3*ENSMUSG0000000397423
Grm8 / P47743 / glutamate receptor, metabotropic 8 / O00222* / glutamate metabotropic receptor 8*ENSMUSG0000002421123
Grm1 / P97772 / Metabotropic glutamate receptor 1 / Q13255* / glutamate metabotropic receptor 1*ENSMUSG0000001982823
Grm5 / Q3UVX5 / glutamate receptor, metabotropic 5 / P41594* / glutamate metabotropic receptor 5*ENSMUSG0000004958322


Protein motifs (from Interpro)
Interpro ID Name
 IPR000337  GPCR, family 3
 IPR001828  Receptor, ligand binding region
 IPR011500  GPCR, family 3, nine cysteines domain
 IPR017978  GPCR family 3, C-terminal
 IPR017979  GPCR, family 3, conserved site
 IPR028082  Periplasmic binding protein-like I


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001582 detection of chemical stimulus involved in sensory perception of sweet taste IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0032467 positive regulation of cytokinesis IEA
 biological_processGO:0050896 response to stimulus IEA
 biological_processGO:0050909 sensory perception of taste IEA
 biological_processGO:0050916 sensory perception of sweet taste IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043235 receptor complex IEA
 cellular_componentGO:1903767 sweet taste receptor complex IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008527 taste receptor activity IEA
 molecular_functionGO:0033041 sweet taste receptor activity IEA


Pathways (from Reactome)
Pathway description
G alpha (i) signalling events
Class C/3 (Metabotropic glutamate/pheromone receptors)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0004209 abnormal sweet taste sensitivity "changes in the ability to perceive a particular flavor or suggestion of something sweet by the chemoreceptors of the gustatory system" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: GnaqMhdadsk10/Gnaq+
Genetic Background: C3HeB/FeJ-GnaqDsk10

Allelic Composition: Tas1r2tm1Csz/Tas1r2tm1Csz,Tas1r3tm1Csz/Tas1r3tm1Csz
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Allelic Composition: Tas1r2tm1Keiw/Tas1r2tm1Keiw
Genetic Background: involves: 129 * C57BL/6J

 MP:0005423 abnormal somatic nervous system physiology "anomalous function of any of the cranial and spinal nerves or their ganglia or the peripheral sensory receptors" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: GnaqMhdadsk10/Gnaq+
Genetic Background: C3HeB/FeJ-GnaqDsk10

Allelic Composition: Tas1r2tm1Csz/Tas1r2tm1Csz,Tas1r3tm1Csz/Tas1r3tm1Csz
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000029072 Q925D8 / Tas1r3 / Taste receptor type 1 member 3 / Q7RTX0* / taste 1 receptor member 3*  / complex






 

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