ENSMUSG00000029072


Mus musculus

Features
Gene ID: ENSMUSG00000029072
  
Biological name :Tas1r3
  
Synonyms : Q925D8 / Tas1r3 / Taste receptor type 1 member 3
  
Possible biological names infered from orthology : Q7RTX0 / taste 1 receptor member 3
  
Species: Mus musculus
  
Chr. number: 4
Strand: -1
Band: E2
Gene start: 155859268
Gene end: 155863362
  
Corresponding Affymetrix probe sets: 10519211 (MoGene1.0st)   1420778_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000030949
NCBI entrez gene - 83771     See in Manteia.
MGI - MGI:1933547
RefSeq - NM_031872
RefSeq Peptide - NP_114078
swissprot - Q925D8
Ensembl - ENSMUSG00000029072
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tas1r3ENSDARG00000006341Danio rerio
 TAS1R3ENSGALG00000032317Gallus gallus
 Q7RTX0ENSG00000169962Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Tas1r1 / taste receptor, type 1, member 1 / Q7RTX1* / taste 1 receptor member 1*ENSMUSG0000002895031
Q925I4 / Tas1r2 / taste receptor, type 1, member 2 / Q8TE23* / taste 1 receptor member 2*ENSMUSG0000002873828
Gprc6a / Q8K4Z6 / G protein-coupled receptor, family C, group 6, member A / Q5T6X5* / G protein-coupled receptor class C group 6 member A*ENSMUSG0000001990528
Grm6 / Q5NCH9 / Metabotropic glutamate receptor 6 / O15303* / glutamate metabotropic receptor 6*ENSMUSG0000000061723
Grm2 / Q14BI2 / Metabotropic glutamate receptor 2 / Q14416* / glutamate metabotropic receptor 2*ENSMUSG0000002319223
Grm3 / Q9QYS2 / Metabotropic glutamate receptor 3 / Q14832* / glutamate metabotropic receptor 3*ENSMUSG0000000397422
Grm5 / Q3UVX5 / glutamate receptor, metabotropic 5 / P41594* / glutamate metabotropic receptor 5*ENSMUSG0000004958322
Grm1 / P97772 / Metabotropic glutamate receptor 1 / Q13255* / glutamate metabotropic receptor 1*ENSMUSG0000001982822
Grm7 / Q68ED2 / Metabotropic glutamate receptor 7 / Q14831* / glutamate metabotropic receptor 7*ENSMUSG0000005675521
Grm4 / glutamate receptor, metabotropic 4 / Q14833* / glutamate metabotropic receptor 4*ENSMUSG0000006323921
Grm8 / P47743 / glutamate receptor, metabotropic 8 / O00222* / glutamate metabotropic receptor 8*ENSMUSG0000002421121


Protein motifs (from Interpro)
Interpro ID Name
 IPR000337  GPCR, family 3
 IPR001828  Receptor, ligand binding region
 IPR011500  GPCR, family 3, nine cysteines domain
 IPR017978  GPCR family 3, C-terminal
 IPR017979  GPCR, family 3, conserved site
 IPR028082  Periplasmic binding protein-like I


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001582 detection of chemical stimulus involved in sensory perception of sweet taste IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0050896 response to stimulus IEA
 biological_processGO:0050909 sensory perception of taste IEA
 biological_processGO:0050916 sensory perception of sweet taste IEA
 biological_processGO:0050917 sensory perception of umami taste IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:1903767 sweet taste receptor complex IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008527 taste receptor activity IEA
 molecular_functionGO:0033041 sweet taste receptor activity IEA


Pathways (from Reactome)
Pathway description
G alpha (i) signalling events
Class C/3 (Metabotropic glutamate/pheromone receptors)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001986 taste sensitivity/ preferences 
Show

Allelic Composition: Trpm5tm1Dgen/Trpm5tm1Dgen
Genetic Background: B6.129P2-Trpm5tm1Dgen

 MP:0004209 abnormal sweet taste sensitivity "changes in the ability to perceive a particular flavor or suggestion of something sweet by the chemoreceptors of the gustatory system" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Scarb1Hdlq1-NZB/BlNJ/Scarb1Hdlq1-NZB/BlNJ
Genetic Background: involves: NZB/BlNJ * SM/J

Allelic Composition: Tas1r3tm1Csz/Tas1r3tm1Csz
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Allelic Composition: Tas1r2tm1Csz/Tas1r2tm1Csz,Tas1r3tm1Csz/Tas1r3tm1Csz
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0004213 abnormal unami taste sensitivity "changes in the ability to perceive a particular flavor or suggestion of something unami (savory) by the chemoreceptors of the gustatory system" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Scarb1Hdlq1-NZB/BlNJ/Scarb1Hdlq1-NZB/BlNJ
Genetic Background: involves: NZB/BlNJ * SM/J

Allelic Composition: Tas1r3tm1Csz/Tas1r3tm1Csz
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0005423 abnormal somatic nervous system physiology "anomalous function of any of the cranial and spinal nerves or their ganglia or the peripheral sensory receptors" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Scarb1Hdlq1-NZB/BlNJ/Scarb1Hdlq1-NZB/BlNJ
Genetic Background: involves: NZB/BlNJ * SM/J

Allelic Composition: Tas1r3tm1Csz/Tas1r3tm1Csz
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Allelic Composition: Tas1r2tm1Csz/Tas1r2tm1Csz,Tas1r3tm1Csz/Tas1r3tm1Csz
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000028950 Tas1r1 / taste receptor, type 1, member 1 / Q7RTX1* / taste 1 receptor member 1*  / complex
 ENSMUSG00000028738 Q925I4 / Tas1r2 / taste receptor, type 1, member 2 / Q8TE23* / taste 1 receptor member 2*  / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr