ENSG00000173612


Homo sapiens

Features
Gene ID: ENSG00000173612
  
Biological name :GPRC6A
  
Synonyms : GPRC6A / G protein-coupled receptor class C group 6 member A / Q5T6X5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: -1
Band: q22.1
Gene start: 116792085
Gene end: 116829037
  
Corresponding Affymetrix probe sets: 1552775_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000309493
Ensembl peptide - ENSP00000357537
Ensembl peptide - ENSP00000433465
NCBI entrez gene - 222545     See in Manteia.
OMIM - 613572
RefSeq - XM_017010476
RefSeq - NM_001286354
RefSeq - NM_001286355
RefSeq - NM_148963
RefSeq - XM_017010475
RefSeq Peptide - NP_683766
RefSeq Peptide - NP_001273283
RefSeq Peptide - NP_001273284
swissprot - Q5T6X5
Ensembl - ENSG00000173612
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gprc6aENSDARG00000005371Danio rerio
 GPRC6AENSGALG00000014925Gallus gallus
 Gprc6aENSMUSG00000019905Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q7RTX0 / TAS1R3 / taste 1 receptor member 3ENSG0000016996227
Q7RTX1 / TAS1R1 / taste 1 receptor member 1ENSG0000017366226
Q8TE23 / TAS1R2 / taste 1 receptor member 2ENSG0000017900225
GRM1 / Q13255 / glutamate metabotropic receptor 1ENSG0000015282224
GRM2 / Q14416 / glutamate metabotropic receptor 2ENSG0000016408224
GRM3 / Q14832 / glutamate metabotropic receptor 3ENSG0000019882224
GRM8 / O00222 / glutamate metabotropic receptor 8ENSG0000017960323
GRM5 / P41594 / glutamate metabotropic receptor 5ENSG0000016895923
GRM4 / Q14833 / glutamate metabotropic receptor 4ENSG0000012449323
GRM6 / O15303 / glutamate metabotropic receptor 6ENSG0000011326222
GRM7 / Q14831 / glutamate metabotropic receptor 7ENSG0000019627722


Protein motifs (from Interpro)
Interpro ID Name
 IPR000337  GPCR, family 3
 IPR001828  Receptor, ligand binding region
 IPR011500  GPCR, family 3, nine cysteines domain
 IPR017978  GPCR family 3, C-terminal
 IPR017979  GPCR, family 3, conserved site
 IPR028082  Periplasmic binding protein-like I


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0019722 calcium-mediated signaling IEA
 biological_processGO:0043200 response to amino acid IDA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA


Pathways (from Reactome)
Pathway description
G alpha (q) signalling events
Class C/3 (Metabotropic glutamate/pheromone receptors)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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