ENSG00000174332


Homo sapiens

Features
Gene ID: ENSG00000174332
  
Biological name :GLIS1
  
Synonyms : GLIS1 / GLIS family zinc finger 1 / Q8NBF1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p32.3
Gene start: 53506237
Gene end: 53738106
  
Corresponding Affymetrix probe sets: 244128_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000486112
Ensembl peptide - ENSP00000309653
NCBI entrez gene - 148979     See in Manteia.
OMIM - 610378
RefSeq - XM_017000411
RefSeq - NM_147193
RefSeq - XM_017000408
RefSeq - XM_017000409
RefSeq - XM_017000410
RefSeq Peptide - NP_671726
swissprot - Q8NBF1
swissprot - A0A0D9SEX9
Ensembl - ENSG00000174332
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 glis1aENSDARG00000068580Danio rerio
 glis1bENSDARG00000027933Danio rerio
 GLIS1ENSGALG00000010721Gallus gallus
 Glis1ENSMUSG00000034762Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GLIS3 / Q8NEA6 / GLIS family zinc finger 3ENSG0000010724943
GLI2 / P10070 / GLI family zinc finger 2ENSG0000007404733
GLI3 / P10071 / GLI family zinc finger 3ENSG0000010657130
GLI1 / P08151 / GLI family zinc finger 1ENSG0000011108728
GLIS2 / Q9BZE0 / GLIS family zinc finger 2ENSG0000012660320
ZIC5 / Q96T25 / Zic family member 5ENSG0000013980019
ZIC2 / O95409 / Zic family member 2ENSG0000004335517
ZIC3 / O60481 / Zic family member 3ENSG0000015692516
ZIC1 / Q15915 / Zic family member 1ENSG0000015297716
ZIC4 / Q8N9L1 / Zic family member 4ENSG0000017496316


Protein motifs (from Interpro)
Interpro ID Name
 IPR013087  Zinc finger C2H2-type
 IPR030430  Zinc finger protein GLIS1
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006366 transcription by RNA polymerase II ISS
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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