ENSG00000174600


Homo sapiens

Features
Gene ID: ENSG00000174600
  
Biological name :CMKLR1
  
Synonyms : chemerin chemokine-like receptor 1 / CMKLR1 / Q99788
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: -1
Band: q23.3
Gene start: 108288044
Gene end: 108339341
  
Corresponding Affymetrix probe sets: 207652_s_at (Human Genome U133 Plus 2.0 Array)   210659_at (Human Genome U133 Plus 2.0 Array)   229121_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000449716
Ensembl peptide - ENSP00000448362
Ensembl peptide - ENSP00000448925
Ensembl peptide - ENSP00000311733
Ensembl peptide - ENSP00000401293
Ensembl peptide - ENSP00000447579
NCBI entrez gene - 1240     See in Manteia.
OMIM - 602351
RefSeq - XM_017018820
RefSeq - NM_001142343
RefSeq - NM_001142344
RefSeq - NM_001142345
RefSeq - NM_004072
RefSeq Peptide - NP_001135817
RefSeq Peptide - NP_004063
RefSeq Peptide - NP_001135816
RefSeq Peptide - NP_001135815
swissprot - F8VYN7
swissprot - F8VSC8
swissprot - Q99788
Ensembl - ENSG00000174600
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cmklr1ENSDARG00000090890Danio rerio
 si:ch211-240b21.4ENSDARG00000110362Danio rerio
 si:ch211-240b21.4ENSDARG00000109654Danio rerio
 CMKLR1ENSGALG00000035182Gallus gallus
 Cmklr1ENSMUSG00000042190Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GPR1 / P46091 / G protein-coupled receptor 1ENSG0000018367133
C3AR1 / Q16581 / complement C3a receptor 1ENSG0000017186032
FPR1 / P21462 / formyl peptide receptor 1ENSG0000017105132
FPR3 / P25089 / formyl peptide receptor 3ENSG0000018747431
FPR2 / P25090 / formyl peptide receptor 2ENSG0000017104931
GPR33 / Q49SQ1 / G protein-coupled receptor 33 (gene/pseudogene)ENSG0000021494331
PTGDR2 / Q9Y5Y4 / prostaglandin D2 receptor 2ENSG0000018313429
C5AR1 / P21730 / complement C5a receptor 1ENSG0000019740529
GPR32 / O75388 / G protein-coupled receptor 32ENSG0000014251128
C5AR2 / Q9P296 / complement component 5a receptor 2ENSG0000013483025
GPR152 / Q8TDT2 / G protein-coupled receptor 152ENSG0000017551423


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR002258  DEZ orphan receptor
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001501 skeletal system development TAS
 biological_processGO:0006935 chemotaxis TAS
 biological_processGO:0006955 immune response TAS
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0010759 positive regulation of macrophage chemotaxis IMP
 biological_processGO:0032088 negative regulation of NF-kappaB transcription factor activity IDA
 biological_processGO:0032695 negative regulation of interleukin-12 production ISS
 biological_processGO:0045600 positive regulation of fat cell differentiation ISS
 biological_processGO:0050848 regulation of calcium-mediated signaling IDA
 biological_processGO:0070098 chemokine-mediated signaling pathway IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane NAS
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity NAS
 molecular_functionGO:0004950 chemokine receptor activity TAS
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Class A/1 (Rhodopsin-like receptors)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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