ENSG00000175463


Homo sapiens

Features
Gene ID: ENSG00000175463
  
Biological name :TBC1D10C
  
Synonyms : Q8IV04 / TBC1D10C / TBC1 domain family member 10C
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: 1
Band: q13.2
Gene start: 67403915
Gene end: 67410089
  
Corresponding Affymetrix probe sets: 228258_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000443654
Ensembl peptide - ENSP00000310193
Ensembl peptide - ENSP00000435543
Ensembl peptide - ENSP00000435829
NCBI entrez gene - 374403     See in Manteia.
OMIM - 610831
RefSeq - XM_011545002
RefSeq - NM_001256508
RefSeq - NM_198517
RefSeq - XM_006718542
RefSeq - XM_006718543
RefSeq - XM_006718544
RefSeq - XM_011545001
RefSeq - XM_006718538
RefSeq - XM_006718539
RefSeq - XM_006718540
RefSeq - XM_006718541
RefSeq Peptide - NP_001243437
RefSeq Peptide - NP_940919
swissprot - Q8IV04
swissprot - E9PSB7
Ensembl - ENSG00000175463
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tbc1d10cENSDARG00000037408Danio rerio
 Q8C9V1ENSMUSG00000040247Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9BXI6 / TBC1D10A / TBC1 domain family member 10AENSG0000009999246
Q4KMP7 / TBC1D10B / TBC1 domain family member 10BENSG0000016922146
AC004997.1ENSG0000024875132
Q92738 / USP6NL / USP6 N-terminal likeENSG0000014842925
GRTP1 / Q5TC63 / growth hormone regulated TBC protein 1ENSG0000013983522
TBC1D3F / TBC1 domain family member 3FENSG0000027595419
TBC1D3D / A0A087WVF3 / TBC1 domain family member 3DENSG0000027441919
TBC1D3E / A0A087X179 / TBC1 domain family member 3EENSG0000027859919
TBC1D3K / A0A087X1G2 / TBC1 domain family member 3KENSG0000027351319
B9A6J9 / TBC1D3L / TBC1 domain family member 3LENSG0000027451219
P0C7X1 / TBC1D3H / TBC1 domain family member 3HENSG0000027422619
Q6DHY5 / TBC1D3G / TBC1 domain family member 3GENSG0000026028719
TBC1D3I / A0A087WXS9 / TBC1 domain family member 3IENSG0000027493319
Q6IPX1 / TBC1D3C / TBC1 domain family member 3CENSG0000027829919
A6NDS4 / TBC1D3B / TBC1 domain family member 3BENSG0000027480819
Q8IZP1 / TBC1D3 / TBC1 domain family member 3ENSG0000027461119
Q86UD7 / TBC1D26 / TBC1 domain family member 26ENSG0000021494612
Q2M2D7 / TBC1D28 / TBC1 domain family member 28ENSG000001893759


Protein motifs (from Interpro)
Interpro ID Name
 IPR000195  Rab-GTPase-TBC domain
 IPR035969  Rab-GTPase-TBC domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006886 intracellular protein transport IBA
 biological_processGO:0031338 regulation of vesicle fusion IBA
 biological_processGO:0042147 retrograde transport, endosome to Golgi IMP
 biological_processGO:0043312 neutrophil degranulation TAS
 biological_processGO:0050869 negative regulation of B cell activation IEA
 biological_processGO:0070373 negative regulation of ERK1 and ERK2 cascade IEA
 biological_processGO:0090630 activation of GTPase activity IBA
 cellular_componentGO:0005622 intracellular IBA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0012505 endomembrane system IBA
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0031527 filopodium membrane IDA
 cellular_componentGO:0101003 ficolin-1-rich granule membrane TAS
 molecular_functionGO:0005096 GTPase activator activity IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0017137 Rab GTPase binding IBA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation
TBC/RABGAPs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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