ENSG00000148429


Homo sapiens

Features
Gene ID: ENSG00000148429
  
Biological name :USP6NL
  
Synonyms : Q92738 / USP6NL / USP6 N-terminal like
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: -1
Band: p14
Gene start: 11453946
Gene end: 11611754
  
Corresponding Affymetrix probe sets: 204761_at (Human Genome U133 Plus 2.0 Array)   238164_at (Human Genome U133 Plus 2.0 Array)   239865_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000277575
Ensembl peptide - ENSP00000368539
Ensembl peptide - ENSP00000476462
Ensembl peptide - ENSP00000476748
NCBI entrez gene - 9712     See in Manteia.
OMIM - 605405
RefSeq - XM_017016973
RefSeq - NM_001080491
RefSeq - NM_014688
RefSeq - XM_006717542
RefSeq - XM_011519762
RefSeq - XM_017016971
RefSeq - XM_017016972
RefSeq Peptide - NP_001073960
RefSeq Peptide - NP_055503
swissprot - Q92738
swissprot - V9GYH2
swissprot - X6RAB3
Ensembl - ENSG00000148429
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 usp6nlENSDARG00000022187Danio rerio
 USP6NLENSGALG00000035563Gallus gallus
 Q80XC3ENSMUSG00000039046Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TBC1D3K / A0A087X1G2 / TBC1 domain family member 3KENSG0000027351322
Q8IZP1 / TBC1D3 / TBC1 domain family member 3ENSG0000027461122
Q6IPX1 / TBC1D3C / TBC1 domain family member 3CENSG0000027829922
A6NDS4 / TBC1D3B / TBC1 domain family member 3BENSG0000027480821
B9A6J9 / TBC1D3L / TBC1 domain family member 3LENSG0000027451221
TBC1D3D / A0A087WVF3 / TBC1 domain family member 3DENSG0000027441921
TBC1D3E / A0A087X179 / TBC1 domain family member 3EENSG0000027859921
TBC1D3F / TBC1 domain family member 3FENSG0000027595421
P0C7X1 / TBC1D3H / TBC1 domain family member 3HENSG0000027422621
Q6DHY5 / TBC1D3G / TBC1 domain family member 3GENSG0000026028721
TBC1D3I / A0A087WXS9 / TBC1 domain family member 3IENSG0000027493321
Q4KMP7 / TBC1D10B / TBC1 domain family member 10BENSG0000016922116
Q9BXI6 / TBC1D10A / TBC1 domain family member 10AENSG0000009999214
Q8IV04 / TBC1D10C / TBC1 domain family member 10CENSG0000017546313
Q86UD7 / TBC1D26 / TBC1 domain family member 26ENSG0000021494612
AC004997.1ENSG0000024875110
Q2M2D7 / TBC1D28 / TBC1 domain family member 28ENSG000001893759
GRTP1 / Q5TC63 / growth hormone regulated TBC protein 1ENSG000001398359


Protein motifs (from Interpro)
Interpro ID Name
 IPR000195  Rab-GTPase-TBC domain
 IPR035969  Rab-GTPase-TBC domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006886 intracellular protein transport IBA
 biological_processGO:0007030 Golgi organization IMP
 biological_processGO:0019068 virion assembly IMP
 biological_processGO:0031338 regulation of vesicle fusion IBA
 biological_processGO:0035526 retrograde transport, plasma membrane to Golgi IMP
 biological_processGO:0043547 positive regulation of GTPase activity IDA
 biological_processGO:0048227 plasma membrane to endosome transport IMP
 biological_processGO:0090630 activation of GTPase activity IBA
 biological_processGO:1903358 regulation of Golgi organization IMP
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0012505 endomembrane system IBA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0032588 trans-Golgi network membrane TAS
 molecular_functionGO:0005096 GTPase activator activity IEA
 molecular_functionGO:0017137 Rab GTPase binding IPI


Pathways (from Reactome)
Pathway description
Retrograde transport at the Trans-Golgi-Network


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000172780 RAB43 / Q86YS6 / RAB43, member RAS oncogene family  / reaction / complex






 

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