ENSG00000183172


Homo sapiens

Features
Gene ID: ENSG00000183172
  
Biological name :SMDT1
  
Synonyms : Q9H4I9 / single-pass membrane protein with aspartate rich tail 1 / SMDT1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 22
Strand: 1
Band: q13.2
Gene start: 42079691
Gene end: 42084284
  
Corresponding Affymetrix probe sets: 225794_s_at (Human Genome U133 Plus 2.0 Array)   225795_at (Human Genome U133 Plus 2.0 Array)   227648_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000327467
Ensembl peptide - ENSP00000402623
NCBI entrez gene - 91689     See in Manteia.
OMIM - 615588
RefSeq - XM_011530509
RefSeq - NM_033318
RefSeq Peptide - NP_201575
swissprot - Q9H4I9
swissprot - F8WDX6
Ensembl - ENSG00000183172
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 smdt1aENSDARG00000095826Danio rerio
 smdt1bENSDARG00000098852Danio rerio
 SMDT1ENSGALG00000011897Gallus gallus
 Smdt1ENSMUSG00000022452Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR018782  Essential MCU regulator, mitochondrial


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006816 calcium ion transport IEA
 biological_processGO:0006851 mitochondrial calcium ion transmembrane transport IMP
 biological_processGO:0036444 calcium import into the mitochondrion IMP
 biological_processGO:0051560 mitochondrial calcium ion homeostasis IMP
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005743 mitochondrial inner membrane TAS
 cellular_componentGO:0005759 mitochondrial matrix TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031305 integral component of mitochondrial inner membrane IDA
 cellular_componentGO:1990246 uniplex complex IDA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Mitochondrial calcium ion transport
Processing of SMDT1


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000105819 PMPCB / O75439 / peptidase, mitochondrial processing beta subunit  / reaction
 ENSG00000141385 AFG3L2 / Q9Y4W6 / AFG3 like matrix AAA peptidase subunit 2  / complex / reaction
 ENSG00000197912 SPG7 / Q9UQ90 / SPG7, paraplegin matrix AAA peptidase subunit  / reaction / complex
 ENSG00000162972 MAIP1 / Q8WWC4 / matrix AAA peptidase interacting protein 1  / complex / reaction
 ENSG00000167085 PHB / P35232 / prohibitin  / reaction / complex
 ENSG00000215021 PHB2 / Q99623 / prohibitin 2  / reaction / complex






 

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