ENSG00000184182


Homo sapiens

Features
Gene ID: ENSG00000184182
  
Biological name :UBE2F
  
Synonyms : Q969M7 / UBE2F / ubiquitin conjugating enzyme E2 F (putative)
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: 1
Band: q37.3
Gene start: 237966827
Gene end: 238042782
  
Corresponding Affymetrix probe sets: 225783_at (Human Genome U133 Plus 2.0 Array)   225787_at (Human Genome U133 Plus 2.0 Array)   225791_at (Human Genome U133 Plus 2.0 Array)   231948_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000408823
Ensembl peptide - ENSP00000478474
Ensembl peptide - ENSP00000414619
Ensembl peptide - ENSP00000412965
Ensembl peptide - ENSP00000410867
Ensembl peptide - ENSP00000410345
Ensembl peptide - ENSP00000409749
Ensembl peptide - ENSP00000272930
Ensembl peptide - ENSP00000386680
Ensembl peptide - ENSP00000387060
Ensembl peptide - ENSP00000387299
Ensembl peptide - ENSP00000389685
Ensembl peptide - ENSP00000390813
Ensembl peptide - ENSP00000393515
Ensembl peptide - ENSP00000396003
Ensembl peptide - ENSP00000396296
Ensembl peptide - ENSP00000396630
Ensembl peptide - ENSP00000399183
Ensembl peptide - ENSP00000406113
Ensembl peptide - ENSP00000408676
NCBI entrez gene - 140739     See in Manteia.
OMIM - 617700
RefSeq - NM_001278306
RefSeq - NM_001278307
RefSeq - NM_001278308
RefSeq - NM_080678
RefSeq - NM_001278305
RefSeq Peptide - NP_001265235
RefSeq Peptide - NP_001265236
RefSeq Peptide - NP_001265237
RefSeq Peptide - NP_542409
RefSeq Peptide - NP_001265234
swissprot - G5E9R6
swissprot - C9JSK8
swissprot - Q969M7
swissprot - C9JFD2
swissprot - C9JF62
swissprot - C9J9P8
swissprot - C9IZ93
swissprot - F2Z363
swissprot - F8WB39
swissprot - F8WCT3
swissprot - F8WD80
swissprot - F8WDQ9
swissprot - F8WFB7
Ensembl - ENSG00000184182
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ube2fENSDARG00000025754Danio rerio
 UBE2FENSGALG00000003812Gallus gallus
 Ube2fENSMUSG00000034343Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
UBE2F-SCLY / UBE2F-SCLY readthrough (NMD candidate)ENSG0000025898470
UBE2M / P61081 / ubiquitin conjugating enzyme E2 MENSG0000013072532


Protein motifs (from Interpro)
Interpro ID Name
 IPR000608  Ubiquitin-conjugating enzyme E2
 IPR016135  Ubiquitin-conjugating enzyme/RWD-like
 IPR023313  Ubiquitin-conjugating enzyme, active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0043687 post-translational protein modification TAS
 biological_processGO:0045116 protein neddylation IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0019788 NEDD8 transferase activity IEA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IBA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IBA


Pathways (from Reactome)
Pathway description
Neddylation
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000129559 NEDD8 / Q15843 / neural precursor cell expressed, developmentally down-regulated 8  / complex / reaction
 ENSG00000043093 Q96GG9 / DCUN1D1 / defective in cullin neddylation 1 domain containing 1  / reaction / complex
 ENSG00000159593 NAE1 / Q13564 / NEDD8 activating enzyme E1 subunit 1  / reaction / complex
 ENSG00000173163 COMMD1 / Q8N668 / copper metabolism domain containing 1  / complex / reaction
 ENSG00000144744 UBA3 / Q8TBC4 / ubiquitin like modifier activating enzyme 3  / complex / reaction
 ENSG00000101997 CCDC22 / O60826 / coiled-coil domain containing 22  / reaction / complex






 

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