ENSG00000043093


Homo sapiens

Features
Gene ID: ENSG00000043093
  
Biological name :DCUN1D1
  
Synonyms : DCUN1D1 / defective in cullin neddylation 1 domain containing 1 / Q96GG9
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: -1
Band: q26.33
Gene start: 182938074
Gene end: 182985953
  
Corresponding Affymetrix probe sets: 218583_s_at (Human Genome U133 Plus 2.0 Array)   222678_s_at (Human Genome U133 Plus 2.0 Array)   222679_s_at (Human Genome U133 Plus 2.0 Array)   237408_at (Human Genome U133 Plus 2.0 Array)   238879_at (Human Genome U133 Plus 2.0 Array)   240781_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000417675
Ensembl peptide - ENSP00000488427
Ensembl peptide - ENSP00000420073
Ensembl peptide - ENSP00000419440
Ensembl peptide - ENSP00000419359
Ensembl peptide - ENSP00000418935
Ensembl peptide - ENSP00000418913
Ensembl peptide - ENSP00000292782
NCBI entrez gene - 54165     See in Manteia.
OMIM - 605905
RefSeq - XM_011512912
RefSeq - XM_017006634
RefSeq - XM_017006633
RefSeq - XM_011512916
RefSeq - XM_011512915
RefSeq - NM_001308101
RefSeq - NM_020640
RefSeq - XM_017006635
RefSeq - XM_011512914
RefSeq Peptide - NP_001295030
RefSeq Peptide - NP_065691
swissprot - Q96GG9
swissprot - C9JVE2
swissprot - F8WC32
swissprot - C9J0B2
swissprot - C9J8R4
swissprot - C9JRU6
swissprot - C9JUW4
Ensembl - ENSG00000043093
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pccaENSDARG00000028982Danio rerio


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MCCC1 / Q96RQ3 / methylcrotonoyl-CoA carboxylase 1ENSG0000007807017
PCCA / P05165 / propionyl-CoA carboxylase alpha subunitENSG0000017519815


Protein motifs (from Interpro)
Interpro ID Name
 IPR005176  Potentiating neddylation domain
 IPR009060  UBA-like superfamily
 IPR014764  Defective-in-cullin neddylation protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008150 biological_process ND
 biological_processGO:0043687 post-translational protein modification TAS
 biological_processGO:0045116 protein neddylation IBA
 biological_processGO:0051443 positive regulation of ubiquitin-protein transferase activity IBA
 cellular_componentGO:0000151 ubiquitin ligase complex IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005829 cytosol IDA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0031624 ubiquitin conjugating enzyme binding IBA
 molecular_functionGO:0032182 ubiquitin-like protein binding IBA
 molecular_functionGO:0097602 cullin family protein binding IBA


Pathways (from Reactome)
Pathway description
Neddylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000100387 RBX1 / P62877 / ring-box 1  / reaction / complex
 ENSG00000130725 UBE2M / P61081 / ubiquitin conjugating enzyme E2 M  / complex / reaction
 ENSG00000129559 NEDD8 / Q15843 / neural precursor cell expressed, developmentally down-regulated 8  / reaction / complex
 ENSG00000055130 CUL1 / Q13616 / cullin 1  / complex / reaction
 ENSG00000101997 CCDC22 / O60826 / coiled-coil domain containing 22  / reaction / complex
 ENSG00000113558 SKP1 / P63208 / S-phase kinase associated protein 1  / complex / reaction
 ENSG00000173163 COMMD1 / Q8N668 / copper metabolism domain containing 1  / reaction / complex
 ENSG00000184182 UBE2F / Q969M7 / ubiquitin conjugating enzyme E2 F (putative)  / reaction / complex






 

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