ENSG00000189337


Homo sapiens

Features
Gene ID: ENSG00000189337
  
Biological name :KAZN
  
Synonyms : KAZN / kazrin, periplakin interacting protein / Q674X7
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: p36.21
Gene start: 13892792
Gene end: 15118043
  
Corresponding Affymetrix probe sets: 213478_at (Human Genome U133 Plus 2.0 Array)   213752_at (Human Genome U133 Plus 2.0 Array)   215138_s_at (Human Genome U133 Plus 2.0 Array)   229144_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000383602
Ensembl peptide - ENSP00000426015
Ensembl peptide - ENSP00000490958
Ensembl peptide - ENSP00000489835
Ensembl peptide - ENSP00000354727
Ensembl peptide - ENSP00000365196
Ensembl peptide - ENSP00000365198
Ensembl peptide - ENSP00000383601
NCBI entrez gene - 23254     See in Manteia.
RefSeq - XM_017000772
RefSeq - XM_011541074
RefSeq - XM_011541075
RefSeq - XM_011541076
RefSeq - XM_011541077
RefSeq - XM_011541080
RefSeq - XM_017000768
RefSeq - XM_017000769
RefSeq - XM_017000770
RefSeq - XM_017000771
RefSeq - NM_001017999
RefSeq - NM_001018000
RefSeq - NM_001018001
RefSeq - NM_015209
RefSeq - NM_201628
RefSeq - XM_005245795
RefSeq Peptide - NP_001018000
RefSeq Peptide - NP_001018001
RefSeq Peptide - NP_056024
RefSeq Peptide - NP_963922
RefSeq Peptide - NP_001017999
swissprot - A0A1B0GWK2
swissprot - Q674X7
swissprot - A0A1B0GTU0
swissprot - B0QYQ6
Ensembl - ENSG00000189337
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 kaznaENSDARG00000076923Danio rerio
 kaznbENSDARG00000006601Danio rerio
 KAZNENSGALG00000013642Gallus gallus
 KaznENSMUSG00000040606Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PPFIA1 / Q13136 / PTPRF interacting protein alpha 1ENSG0000013162629
O75335 / PPFIA4 / PTPRF interacting protein alpha 4ENSG0000014384728
O75145 / PPFIA3 / PTPRF interacting protein alpha 3ENSG0000017738028
O75334 / PPFIA2 / PTPRF interacting protein alpha 2ENSG0000013922027
Q86W92 / PPFIBP1 / PPFIA binding protein 1ENSG0000011084121
Q8ND30 / PPFIBP2 / PPFIA binding protein 2ENSG0000016638720


Protein motifs (from Interpro)
Interpro ID Name
 IPR001660  Sterile alpha motif domain
 IPR013761  Sterile alpha motif/pointed domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0031424 keratinization IEA
 biological_processGO:0070268 cornification TAS
 cellular_componentGO:0001533 cornified envelope IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0016607 nuclear speck IDA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030057 desmosome IDA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Formation of the cornified envelope


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000118898 PPL / O60437 / periplakin  / reaction / complex






 

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