ENSG00000205268


Homo sapiens

Features
Gene ID: ENSG00000205268
  
Biological name :PDE7A
  
Synonyms : PDE7A / phosphodiesterase 7A / Q13946
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 8
Strand: -1
Band: q13.1
Gene start: 65717510
Gene end: 65842322
  
Corresponding Affymetrix probe sets: 1552343_s_at (Human Genome U133 Plus 2.0 Array)   223358_s_at (Human Genome U133 Plus 2.0 Array)   223359_s_at (Human Genome U133 Plus 2.0 Array)   224046_s_at (Human Genome U133 Plus 2.0 Array)   230500_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000430262
Ensembl peptide - ENSP00000368730
Ensembl peptide - ENSP00000379881
Ensembl peptide - ENSP00000385632
NCBI entrez gene - 5150     See in Manteia.
OMIM - 171885
RefSeq - XM_017013538
RefSeq - NM_001242318
RefSeq - NM_002603
RefSeq - XM_011517540
RefSeq Peptide - NP_002594
RefSeq Peptide - NP_001229247
swissprot - Q13946
swissprot - E5RG23
Ensembl - ENSG00000205268
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pde7aENSDARG00000045305Danio rerio
 PDE7AENSGALG00000038395Gallus gallus
 Pde7aENSMUSG00000069094Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PDE7B / Q9NP56 / phosphodiesterase 7BENSG0000017140854
PDE4A / P27815 / phosphodiesterase 4AENSG0000006598931
PDE4C / Q08493 / phosphodiesterase 4CENSG0000010565030
PDE4D / Q08499 / phosphodiesterase 4DENSG0000011344830
Q08493 / AC008397.2 / cAMP-specific 3,5-cyclic phosphodiesterase 4C ENSG0000028518830
PDE4B / Q07343 / phosphodiesterase 4BENSG0000018458829
PDE8A / O60658 / phosphodiesterase 8AENSG0000007341726
PDE8B / O95263 / phosphodiesterase 8BENSG0000011323126
AC022414.1 / high affinity cAMP-specific and IBMX-insensitive 3,5-cyclic phosphodiesterase 8B isoform 11 ENSG0000028476224
PDE1C / Q14123 / phosphodiesterase 1CENSG0000015467824
PDE1A / P54750 / phosphodiesterase 1AENSG0000011525223
PDE1B / Q01064 / phosphodiesterase 1BENSG0000012336022


Protein motifs (from Interpro)
Interpro ID Name
 IPR002073  3"5"-cyclic nucleotide phosphodiesterase, catalytic domain
 IPR003607  HD/PDEase domain
 IPR023088  3"5"-cyclic nucleotide phosphodiesterase
 IPR023174  3"5"-cyclic nucleotide phosphodiesterase, conserved site
 IPR036971  3"5"-cyclic nucleotide phosphodiesterase, catalytic domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006198 cAMP catabolic process IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0004114 3",5"-cyclic-nucleotide phosphodiesterase activity IEA
 molecular_functionGO:0004115 3",5"-cyclic-AMP phosphodiesterase activity IDA
 molecular_functionGO:0008081 phosphoric diester hydrolase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
G alpha (s) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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