ENSG00000274211


Homo sapiens

Features
Gene ID: ENSG00000274211
  
Biological name :SOCS7
  
Synonyms : O14512 / SOCS7 / suppressor of cytokine signaling 7
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: 1
Band: q12
Gene start: 38352228
Gene end: 38405593
  
Corresponding Affymetrix probe sets: 214015_at (Human Genome U133 Plus 2.0 Array)   226572_at (Human Genome U133 Plus 2.0 Array)   228662_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000482229
Ensembl peptide - ENSP00000484381
Ensembl peptide - ENSP00000482278
NCBI entrez gene - 30837     See in Manteia.
OMIM - 608788
RefSeq - XM_017024551
RefSeq - XM_017024552
RefSeq - NM_014598
RefSeq Peptide - NP_055413
swissprot - O14512
swissprot - A0A087X1Q5
swissprot - A0A087WZ14
Ensembl - ENSG00000274211
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 socs7ENSDARG00000077018Danio rerio
 ENSGALG00000040658Gallus gallus
 Socs7ENSMUSG00000038485Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SOCS6 / O14544 / suppressor of cytokine signaling 6ENSG0000017067722
SOCS5 / O75159 / suppressor of cytokine signaling 5ENSG0000017115015
SOCS4 / Q8WXH5 / suppressor of cytokine signaling 4ENSG0000018000814
CISH / Q9NSE2 / cytokine inducible SH2 containing proteinENSG0000011473711
SOCS2 / O14508 / suppressor of cytokine signaling 2ENSG0000012083310
SOCS3 / O14543 / suppressor of cytokine signaling 3ENSG000001845579
SOCS1 / O15524 / suppressor of cytokine signaling 1ENSG000001853389


Protein motifs (from Interpro)
Interpro ID Name
 IPR000980  SH2 domain
 IPR001496  SOCS box domain
 IPR028423  Suppressor of cytokine signalling 7
 IPR035866  SOCS7, SH2 domain
 IPR036036  SOCS box-like domain superfamily
 IPR036860  SH2 domain superfamily
 IPR037346  SOCS7, SOCS box domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006469 negative regulation of protein kinase activity IBA
 biological_processGO:0008150 biological_process ND
 biological_processGO:0008286 insulin receptor signaling pathway IEA
 biological_processGO:0009968 negative regulation of signal transduction IEA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0019221 cytokine-mediated signaling pathway IBA
 biological_processGO:0021799 cerebral cortex radially oriented cell migration IEA
 biological_processGO:0021819 layer formation in cerebral cortex IEA
 biological_processGO:0021942 radial glia guided migration of Purkinje cell IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0040008 regulation of growth IEA
 biological_processGO:0045444 fat cell differentiation IEA
 biological_processGO:0046426 negative regulation of JAK-STAT cascade IBA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0004860 protein kinase inhibitor activity IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0017124 SH3 domain binding NAS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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