ENSGALG00000002739


Gallus gallus

Features
Gene ID: ENSGALG00000002739
  
Biological name :INPP5K
  
Synonyms : inositol polyphosphate 5-phosphatase K / INPP5K
  
Possible biological names infered from orthology : Q8C5L6 / Q9BT40
  
Species: Gallus gallus
  
Chr. number: 19
Strand: -1
Band:
Gene start: 5245126
Gene end: 5276310
  
Corresponding Affymetrix probe sets: Gga.7109.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000004309
Ensembl peptide - ENSGALP00000046981
Ensembl peptide - ENSGALP00000044730
NCBI entrez gene - 771549     See in Manteia.
RefSeq - NM_001282294
RefSeq Peptide - NP_001269223
swissprot - A0A1D5P2T2
swissprot - A0A1D5NWJ0
swissprot - F1N8B6
Ensembl - ENSGALG00000002739
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 inpp5kaENSDARG00000099563Danio rerio
 inpp5kbENSDARG00000078618Danio rerio
 INPP5KENSG00000132376Homo sapiens
 Inpp5kENSMUSG00000006127Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
INPP5J / inositol polyphosphate-5-phosphatase J / P59644* / Q15735* / Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A *ENSGALG0000002326644
OCRL / OCRL, inositol polyphosphate-5-phosphatase / Q01968* / Q6NVF0* / Inositol polyphosphate 5-phosphatase OCRL-1 *ENSGALG0000000392028
INPP5B / inositol polyphosphate-5-phosphatase B / P32019* / Q8K337* / Type II inositol 1,4,5-trisphosphate 5-phosphatase *ENSGALG0000000160627
SYNJ2 / synaptojanin 2 / O15056* / Q9D2G5*ENSGALG0000001372724
SYNJ1 / synaptojanin 1 / O43426*ENSGALG0000003431724
INPPL1 / inositol polyphosphate phosphatase like 1 / O15357* / Q6P549* / Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 *ENSGALG0000000433622
INPP5D / inositol polyphosphate-5-phosphatase D / Q92835* / Q9ES52* / Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 *ENSGALG0000003549819
INPP5E / inositol polyphosphate-5-phosphatase E / Q9JII1* / Q9NRR6* / 72 kDa inositol polyphosphate 5-phosphatase *ENSGALG0000000196418


Protein motifs (from Interpro)
Interpro ID Name
 IPR000300  Inositol polyphosphate-related phosphatase
 IPR005135  Endonuclease/exonuclease/phosphatase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001701 in utero embryonic development IEA
 biological_processGO:0001933 negative regulation of protein phosphorylation IEA
 biological_processGO:0005979 regulation of glycogen biosynthetic process IEA
 biological_processGO:0006469 negative regulation of protein kinase activity IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0010801 negative regulation of peptidyl-threonine phosphorylation IEA
 biological_processGO:0010829 negative regulation of glucose transmembrane transport IEA
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0032868 response to insulin IEA
 biological_processGO:0032869 cellular response to insulin stimulus IEA
 biological_processGO:0032870 cellular response to hormone stimulus IEA
 biological_processGO:0033137 negative regulation of peptidyl-serine phosphorylation IEA
 biological_processGO:0035305 negative regulation of dephosphorylation IEA
 biological_processGO:0035810 positive regulation of urine volume IEA
 biological_processGO:0042593 glucose homeostasis IEA
 biological_processGO:0043407 negative regulation of MAP kinase activity IEA
 biological_processGO:0043922 negative regulation by host of viral transcription IEA
 biological_processGO:0045719 negative regulation of glycogen biosynthetic process IEA
 biological_processGO:0045869 negative regulation of single stranded viral RNA replication via double stranded DNA intermediate IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0046627 negative regulation of insulin receptor signaling pathway IEA
 biological_processGO:0046855 inositol phosphate dephosphorylation IEA
 biological_processGO:0046856 phosphatidylinositol dephosphorylation IEA
 biological_processGO:0051497 negative regulation of stress fiber assembly IEA
 biological_processGO:0051898 negative regulation of protein kinase B signaling IEA
 biological_processGO:0051926 negative regulation of calcium ion transport IEA
 biological_processGO:0071320 cellular response to cAMP IEA
 biological_processGO:0071356 cellular response to tumor necrosis factor IEA
 biological_processGO:0071364 cellular response to epidermal growth factor stimulus IEA
 biological_processGO:0072659 protein localization to plasma membrane IEA
 biological_processGO:0090315 negative regulation of protein targeting to membrane IEA
 biological_processGO:0097178 ruffle assembly IEA
 biological_processGO:2000466 negative regulation of glycogen (starch) synthase activity IEA
 biological_processGO:2001153 positive regulation of renal water transport IEA
 cellular_componentGO:0001726 ruffle IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005802 trans-Golgi network IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0032587 ruffle membrane IEA
 cellular_componentGO:0043005 neuron projection IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity IEA
 molecular_functionGO:0005000 vasopressin receptor activity IEA
 molecular_functionGO:0016312 inositol bisphosphate phosphatase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity IEA
 molecular_functionGO:0034594 phosphatidylinositol trisphosphate phosphatase activity IEA
 molecular_functionGO:0034595 phosphatidylinositol phosphate 5-phosphatase activity IEA
 molecular_functionGO:0046030 inositol trisphosphate phosphatase activity IEA


Pathways (from Reactome)
Pathway description
Synthesis of PIPs at the plasma membrane


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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