ENSGALG00000003920


Gallus gallus

Features
Gene ID: ENSGALG00000003920
  
Biological name :OCRL
  
Synonyms : OCRL / OCRL, inositol polyphosphate-5-phosphatase
  
Possible biological names infered from orthology : Inositol polyphosphate 5-phosphatase OCRL-1 / Q01968 / Q6NVF0
  
Species: Gallus gallus
  
Chr. number: 4
Strand: -1
Band:
Gene start: 1665052
Gene end: 1683087
  
Corresponding Affymetrix probe sets: Gga.15721.1.S1_s_at (Chicken Array)   Gga.15763.1.S1_s_at (Chicken Array)   GgaAffx.26061.1.S1_at (Chicken Array)   GgaAffx.26061.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000039750
NCBI entrez gene - 422136     See in Manteia.
RefSeq - XM_004940575
RefSeq - XM_420138
RefSeq - XM_004940576
RefSeq - XM_004940577
swissprot - F1NY08
Ensembl - ENSGALG00000003920
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ocrlENSDARG00000078106Danio rerio
 OCRLENSG00000122126Homo sapiens
 OcrlENSMUSG00000001173Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
INPP5B / inositol polyphosphate-5-phosphatase B / P32019* / Q8K337* / Type II inositol 1,4,5-trisphosphate 5-phosphatase *ENSGALG0000000160641
SYNJ1 / synaptojanin 1 / O43426*ENSGALG0000003431721
SYNJ2 / synaptojanin 2 / O15056* / Q9D2G5*ENSGALG0000001372721
INPP5D / inositol polyphosphate-5-phosphatase D / Q92835* / Q9ES52* / Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 *ENSGALG0000003549816
INPPL1 / inositol polyphosphate phosphatase like 1 / O15357* / Q6P549* / Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 *ENSGALG0000000433616
INPP5K / inositol polyphosphate 5-phosphatase K / Q8C5L6* / Q9BT40*ENSGALG0000000273914
INPP5J / inositol polyphosphate-5-phosphatase J / P59644* / Q15735* / Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A *ENSGALG0000002326614
INPP5E / inositol polyphosphate-5-phosphatase E / Q9JII1* / Q9NRR6* / 72 kDa inositol polyphosphate 5-phosphatase *ENSGALG0000000196413


Protein motifs (from Interpro)
Interpro ID Name
 IPR000198  Rho GTPase-activating protein domain
 IPR000300  Inositol polyphosphate-related phosphatase
 IPR005135  Endonuclease/exonuclease/phosphatase
 IPR008936  Rho GTPase activation protein
 IPR031995  Inositol polyphosphate 5-phosphatase, clathrin binding domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001701 in utero embryonic development IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0043087 regulation of GTPase activity IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0046856 phosphatidylinositol dephosphorylation IEA
 biological_processGO:0060271 cilium assembly IEA
 cellular_componentGO:0001750 photoreceptor outer segment IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005769 early endosome IEA
 cellular_componentGO:0005802 trans-Golgi network IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0030136 clathrin-coated vesicle IEA
 molecular_functionGO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity IEA
 molecular_functionGO:0005096 GTPase activator activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0048365 Rac GTPase binding IEA
 molecular_functionGO:0052745 inositol phosphate phosphatase activity IEA


Pathways (from Reactome)
Pathway description
Synthesis of PIPs at the plasma membrane
Synthesis of PIPs at the Golgi membrane
Synthesis of IP2, IP, and Ins in the cytosol
Synthesis of IP3 and IP4 in the cytosol
Rho GTPase cycle
Golgi Associated Vesicle Biogenesis
Clathrin-mediated endocytosis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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