ENSGALG00000001964


Gallus gallus

Features
Gene ID: ENSGALG00000001964
  
Biological name :INPP5E
  
Synonyms : inositol polyphosphate-5-phosphatase E / INPP5E
  
Possible biological names infered from orthology : 72 kDa inositol polyphosphate 5-phosphatase / Q9JII1 / Q9NRR6
  
Species: Gallus gallus
  
Chr. number: 17
Strand: 1
Band:
Gene start: 8360606
Gene end: 8367535
  
Corresponding Affymetrix probe sets: Gga.4744.2.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000003041
NCBI entrez gene - 417135     See in Manteia.
RefSeq - XM_015279803
RefSeq - XM_415418
swissprot - F1P5J6
Ensembl - ENSGALG00000001964
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 inpp5eENSDARG00000103926Danio rerio
 INPP5EENSG00000148384Homo sapiens
 Inpp5eENSMUSG00000026925Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SYNJ2 / synaptojanin 2 / O15056* / Q9D2G5*ENSGALG0000001372723
SYNJ1 / synaptojanin 1 / O43426*ENSGALG0000003431722
OCRL / OCRL, inositol polyphosphate-5-phosphatase / Q01968* / Q6NVF0* / Inositol polyphosphate 5-phosphatase OCRL-1 *ENSGALG0000000392018
INPP5D / inositol polyphosphate-5-phosphatase D / Q92835* / Q9ES52* / Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 *ENSGALG0000003549818
INPPL1 / inositol polyphosphate phosphatase like 1 / O15357* / Q6P549* / Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 *ENSGALG0000000433617
INPP5B / inositol polyphosphate-5-phosphatase B / P32019* / Q8K337* / Type II inositol 1,4,5-trisphosphate 5-phosphatase *ENSGALG0000000160616
INPP5K / inositol polyphosphate 5-phosphatase K / Q8C5L6* / Q9BT40*ENSGALG0000000273913
INPP5J / inositol polyphosphate-5-phosphatase J / P59644* / Q15735* / Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A *ENSGALG0000002326612


Protein motifs (from Interpro)
Interpro ID Name
 IPR000300  Inositol polyphosphate-related phosphatase
 IPR005135  Endonuclease/exonuclease/phosphatase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0046488 phosphatidylinositol metabolic process IEA
 biological_processGO:0046855 inositol phosphate dephosphorylation IEA
 biological_processGO:0046856 phosphatidylinositol dephosphorylation IEA
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005930 axoneme IEA
 molecular_functionGO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Synthesis of PIPs at the Golgi membrane
ARL13B-mediated ciliary trafficking of INPP5E


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000015412 ARL13B / ADP ribosylation factor like GTPase 13B / Q3SXY8* / Q640N2* / ADP-ribosylation factor-like protein 13B *  / reaction / complex
 ENSGALG00000033062 PDE6D / phosphodiesterase 6D / O43924* / O55057* / Retinal rod rhodopsin-sensitive cGMP 3,5-cyclic phosphodiesterase subunit delta *  / complex / reaction






 

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