ENSGALG00000005725


Gallus gallus

Features
Gene ID: ENSGALG00000005725
  
Biological name :CSF1R
  
Synonyms : CSF1R / Gallus gallus colony stimulating factor 1 receptor (CSF1R), mRNA.
  
Possible biological names infered from orthology : colony stimulating factor 1 receptor / Macrophage colony-stimulating factor 1 receptor / P07333 / P09581
  
Species: Gallus gallus
  
Chr. number: 13
Strand: 1
Band:
Gene start: 13275947
Gene end: 13293798
  
Corresponding Affymetrix probe sets: Gga.19453.1.S1_at (Chicken Array)   Gga.19453.1.S1_s_at (Chicken Array)   Gga.4070.1.S1_at (Chicken Array)   GgaAffx.26579.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000009176
NCBI entrez gene - 396406     See in Manteia.
RefSeq - NM_001321517
RefSeq Peptide - NP_001308446
swissprot - F1N869
Ensembl - ENSGALG00000005725
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 csf1raENSDARG00000102986Danio rerio
 csf1rbENSDARG00000053624Danio rerio
 CSF1RENSG00000182578Homo sapiens
 Csf1rENSMUSG00000024621Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
KIT / Q08156 / Mast/stem cell growth factor receptor Kit / P05532* / P10721* / KIT proto-oncogene receptor tyrosine kinase*ENSGALG0000003863440
PDGFRA / platelet derived growth factor receptor alpha / P16234* / P26618* / Mus musculus platelet derived growth factor receptor, alpha polypeptide (Pdgfra), transcript variant 4, mRNA.*ENSGALG0000001392934
PDGFRB / platelet derived growth factor receptor beta / P09619* / platelet-derived growth factor receptor beta isoform 2 *ENSGALG0000003061333
KDR / vascular endothelial growth factor receptor 2 precursor / P35968* / kinase insert domain receptor*ENSGALG0000001390731
FLT4 / fms related tyrosine kinase 4 / P35916* / P35917* / Vascular endothelial growth factor receptor 3 *ENSGALG0000000580231
FLT1 / vascular endothelial growth factor receptor 1 precursor / P17948* / fms related tyrosine kinase 1*ENSGALG0000001709130
ENSGALG0000000764630
FLT3 / fms related tyrosine kinase 3 / P36888*ENSGALG0000003572629
FGFR1 / fibroblast growth factor receptor 1 precursor / P11362* / P16092* / fibroblast growth factor receptor 1*ENSGALG0000003978623
FGFR3 / fibroblast growth factor receptor 3 / P22607* / Mus musculus fibroblast growth factor receptor 3 (Fgfr3), transcript variant 6, mRNA.*ENSGALG0000001570823
FGFR2 / P18461 / Fibroblast growth factor receptor 2 / P21802* / fibroblast growth factor receptor 2 isoform 3 *ENSGALG0000000949523
FGFR4 / fibroblast growth factor receptor 4 / P22455*ENSGALG0000002854322
RET / ret proto-oncogene / P07949* / P35546* / Proto-onco tyrosine-protein kinase receptor Ret Soluble RET kinase fragment Extracellular cell-membrane anchored RET cadherin 120 kDa fragment*ENSGALG0000000255522


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR001245  Serine-threonine/tyrosine-protein kinase, catalytic domain
 IPR001824  Tyrosine-protein kinase, receptor class III, conserved site
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR008266  Tyrosine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR013783  Immunoglobulin-like fold
 IPR017441  Protein kinase, ATP binding site
 IPR020635  Tyrosine-protein kinase, catalytic domain
 IPR030658  Macrophage colony-stimulating factor 1 receptor


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001934 positive regulation of protein phosphorylation IEA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway IEA
 biological_processGO:0007411 axon guidance IEA
 biological_processGO:0008283 cell proliferation IEA
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0008360 regulation of cell shape IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation IEA
 biological_processGO:0019221 cytokine-mediated signaling pathway IEA
 biological_processGO:0021772 olfactory bulb development IEA
 biological_processGO:0021879 forebrain neuron differentiation IEA
 biological_processGO:0030097 hemopoiesis IEA
 biological_processGO:0030316 osteoclast differentiation IEA
 biological_processGO:0030335 positive regulation of cell migration IEA
 biological_processGO:0031529 ruffle organization IEA
 biological_processGO:0036006 cellular response to macrophage colony-stimulating factor stimulus IEA
 biological_processGO:0038145 macrophage colony-stimulating factor signaling pathway IEA
 biological_processGO:0042531 positive regulation of tyrosine phosphorylation of STAT protein IEA
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 biological_processGO:0045217 cell-cell junction maintenance IEA
 biological_processGO:0046488 phosphatidylinositol metabolic process IEA
 biological_processGO:0046777 protein autophosphorylation IEA
 biological_processGO:0048015 phosphatidylinositol-mediated signaling IEA
 biological_processGO:0061098 positive regulation of protein tyrosine kinase activity IEA
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IEA
 biological_processGO:0071345 cellular response to cytokine stimulus IEA
 biological_processGO:0071902 positive regulation of protein serine/threonine kinase activity IEA
 biological_processGO:0090197 positive regulation of chemokine secretion IEA
 biological_processGO:2000147 positive regulation of cell motility IEA
 biological_processGO:2000249 regulation of actin cytoskeleton reorganization IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 cellular_componentGO:1990682 CSF1-CSF1R complex IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004713 protein tyrosine kinase activity IEA
 molecular_functionGO:0004714 transmembrane receptor protein tyrosine kinase activity IEA
 molecular_functionGO:0005011 macrophage colony-stimulating factor receptor activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0019903 protein phosphatase binding IEA
 molecular_functionGO:0019955 cytokine binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA


Pathways (from Reactome)
Pathway description
Other interleukin signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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