ENSGALG00000005909


Gallus gallus

Features
Gene ID: ENSGALG00000005909
  
Biological name :GATA2
  
Synonyms : GATA2 / GATA-binding factor 2 / P23824
  
Possible biological names infered from orthology : GATA binding protein 2 / Mus musculus GATA binding protein 2 (Gata2), transcript variant 2, mRNA. / O09100 / P23769
  
Species: Gallus gallus
  
Chr. number: 12
Strand: 1
Band:
Gene start: 9198668
Gene end: 9214691
  
Corresponding Affymetrix probe sets: Gga.745.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000030109
Ensembl peptide - ENSGALP00000053966
NCBI entrez gene - 416018     See in Manteia.
RefSeq - XM_015293080
RefSeq - NM_001003797
RefSeq - XM_015293078
RefSeq - XM_015293079
RefSeq - XM_015293077
RefSeq Peptide - NP_001003797
swissprot - P23824
Ensembl - ENSGALG00000005909
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gata2aENSDARG00000059327Danio rerio
 GATA2ENSG00000179348Homo sapiens
 Gata2ENSMUSG00000015053Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GATA3 / P23825 / GATA-binding factor 3 / P23771* / P23772* / GATA binding protein 3* / Mus musculus GATA binding protein 3 (Gata3), transcript variant 3, mRNA.*ENSGALG0000002927065
GATA5 / transcription factor GATA-5 / P97489* / Q9BWX5* / GATA binding protein 5*ENSGALG0000000535230
GATA4 / GATA binding protein 4 / P43694* / Q08369* / Transcription factor GATA-4 *ENSGALG0000001666229
GATA6 / transcription factor GATA-6 / Q61169* / Q92908* / GATA binding protein 6*ENSGALG0000001497628
TRPS1 / transcriptional repressor GATA binding 1 / Q9UHF7*ENSGALG0000003170019


Protein motifs (from Interpro)
Interpro ID Name
 IPR000679  Zinc finger, GATA-type
 IPR013088  Zinc finger, NHR/GATA-type
 IPR016374  Transcription factor, GATA-2/3
 IPR029522  Transcription factor GATA-2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0001655 urogenital system development IEA
 biological_processGO:0001709 cell fate determination IEA
 biological_processGO:0001892 embryonic placenta development IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0010725 regulation of primitive erythrocyte differentiation IEA
 biological_processGO:0021514 ventral spinal cord interneuron differentiation IEA
 biological_processGO:0021533 cell differentiation in hindbrain IEA
 biological_processGO:0021902 commitment of neuronal cell to specific neuron type in forebrain IEA
 biological_processGO:0021954 central nervous system neuron development IEA
 biological_processGO:0021983 pituitary gland development IEA
 biological_processGO:0030097 hemopoiesis IEA
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0030182 neuron differentiation IEA
 biological_processGO:0035019 somatic stem cell population maintenance IEA
 biological_processGO:0035065 regulation of histone acetylation IEA
 biological_processGO:0035854 eosinophil fate commitment IEA
 biological_processGO:0042472 inner ear morphogenesis IEA
 biological_processGO:0045599 negative regulation of fat cell differentiation IEA
 biological_processGO:0045638 negative regulation of myeloid cell differentiation IEA
 biological_processGO:0045648 positive regulation of erythrocyte differentiation IEA
 biological_processGO:0045650 negative regulation of macrophage differentiation IEA
 biological_processGO:0045654 positive regulation of megakaryocyte differentiation IEA
 biological_processGO:0045746 negative regulation of Notch signaling pathway IEA
 biological_processGO:0045766 positive regulation of angiogenesis IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0048469 cell maturation IEA
 biological_processGO:0048663 neuron fate commitment IEA
 biological_processGO:0048873 homeostasis of number of cells within a tissue IEA
 biological_processGO:0060216 definitive hemopoiesis IEA
 biological_processGO:0060872 semicircular canal development IEA
 biological_processGO:0070345 negative regulation of fat cell proliferation IEA
 biological_processGO:0097154 GABAergic neuron differentiation IEA
 biological_processGO:2000178 negative regulation of neural precursor cell proliferation IEA
 biological_processGO:2000352 negative regulation of endothelial cell apoptotic process IEA
 biological_processGO:2000977 regulation of forebrain neuron differentiation IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005667 transcription factor complex IBA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IBA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding IEA
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0001085 RNA polymerase II transcription factor binding IBA
 molecular_functionGO:0001158 enhancer sequence-specific DNA binding IEA
 molecular_functionGO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003682 chromatin binding IBA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008134 transcription factor binding IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0070742 C2H2 zinc finger domain binding IEA


Pathways (from Reactome)
Pathway description
RUNX1 regulates transcription of genes involved in differentiation of HSCs
Factors involved in megakaryocyte development and platelet production


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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