ENSGALG00000008346


Gallus gallus

Features
Gene ID: ENSGALG00000008346
  
Biological name :CASP18
  
Synonyms : CASP18
  
Possible biological names infered from orthology :
  
Species: Gallus gallus
  
Chr. number: 7
Strand: 1
Band:
Gene start: 11489044
Gene end: 11497197
  
Corresponding Affymetrix probe sets: GgaAffx.5264.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000038353
NCBI entrez gene - 693266     See in Manteia.
RefSeq - NM_001044689
RefSeq - XM_015289447
RefSeq Peptide - NP_001038154
swissprot - Q4JQQ0
Ensembl - ENSGALG00000008346
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 casp8ENSDARG00000058325Danio rerio


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CASP8 / caspase-8 / O89110* / Q14790* / Caspase-8 Caspase-8 subunit p18 Caspase-8 subunit p10*ENSGALG0000000835551
CASP10 / caspase 10 / Q92851*ENSGALG0000004649437
CASP9 / caspase 9 / P55211* / Q8C3Q9* / Mus musculus caspase 9 (Casp9), transcript variant 3, mRNA.*ENSGALG0000000136620
CASP3 / caspase 3 / P42574* / P70677* / Caspase-3 Caspase-3 subunit p17 Caspase-3 subunit p12*ENSGALG0000001063819
CASP7 / caspase 7 / P55210* / P97864* / Caspase-7 Caspase-7 subunit p20 Caspase-7 subunit p11*ENSGALG0000000893319
CASP6 / caspase-6 / O08738* / P55212* / Caspase-6 Caspase-6 subunit p18 Caspase-6 subunit p11*ENSGALG0000001218618
CASP2 / caspase-2 / P29594* / P42575* / Caspase-2 Caspase-2 subunit p18 Caspase-2 subunit p13 Caspase-2 subunit p12*ENSGALG0000001469818


Protein motifs (from Interpro)
Interpro ID Name
 IPR001309  Peptidase C14, p20 domain
 IPR001875  Death effector domain
 IPR002138  Peptidase C14, caspase non-catalytic subunit p10
 IPR011029  Death-like domain superfamily
 IPR015917  Peptidase C14A, caspase catalytic domain
 IPR016129  Peptidase family C14A, His active site
 IPR029030  Caspase-like domain superfamily
 IPR033139  Peptidase family C14A, cysteine active site
 IPR033170  Caspase-8


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0008625 extrinsic apoptotic signaling pathway via death domain receptors IBA
 biological_processGO:0030225 macrophage differentiation IBA
 biological_processGO:0042981 regulation of apoptotic process IEA
 biological_processGO:0097194 execution phase of apoptosis IBA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0004197 cysteine-type endopeptidase activity IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008234 cysteine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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