ENSGALG00000012186


Gallus gallus

Features
Gene ID: ENSGALG00000012186
  
Biological name :CASP6
  
Synonyms : CASP6 / caspase-6
  
Possible biological names infered from orthology : Caspase-6 Caspase-6 subunit p18 Caspase-6 subunit p11 / O08738 / P55212
  
Species: Gallus gallus
  
Chr. number: 4
Strand: 1
Band:
Gene start: 58517323
Gene end: 58526130
  
Corresponding Affymetrix probe sets: Gga.2960.1.S1_at (Chicken Array)   GgaAffx.21232.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000054851
Ensembl peptide - ENSGALP00000019870
NCBI entrez gene - 395477     See in Manteia.
RefSeq - XM_015276126
RefSeq - NM_204726
RefSeq - XM_015276124
RefSeq - XM_015276125
RefSeq Peptide - NP_990057
swissprot - F1NEL6
swissprot - A0A1D5PPP7
Ensembl - ENSGALG00000012186
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 casp6ENSDARG00000093405Danio rerio
 casp6l1ENSDARG00000025608Danio rerio
 casp6l2ENSDARG00000070368Danio rerio
 CASP6ENSG00000138794Homo sapiens
 Casp6ENSMUSG00000027997Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CASP7 / caspase 7 / P55210* / P97864* / Caspase-7 Caspase-7 subunit p20 Caspase-7 subunit p11*ENSGALG0000000893336
CASP3 / caspase 3 / P42574* / P70677* / Caspase-3 Caspase-3 subunit p17 Caspase-3 subunit p12*ENSGALG0000001063832
CASP8 / caspase-8 / O89110* / Q14790* / Caspase-8 Caspase-8 subunit p18 Caspase-8 subunit p10*ENSGALG0000000835531
CASP9 / caspase 9 / P55211* / Q8C3Q9* / Mus musculus caspase 9 (Casp9), transcript variant 3, mRNA.*ENSGALG0000000136630
CASP10 / caspase 10 / Q92851*ENSGALG0000004649429
CASP18ENSGALG0000000834627
CASP2 / caspase-2 / P29594* / P42575* / Caspase-2 Caspase-2 subunit p18 Caspase-2 subunit p13 Caspase-2 subunit p12*ENSGALG0000001469826


Protein motifs (from Interpro)
Interpro ID Name
 IPR001309  Peptidase C14, p20 domain
 IPR002138  Peptidase C14, caspase non-catalytic subunit p10
 IPR015917  Peptidase C14A, caspase catalytic domain
 IPR029030  Caspase-like domain superfamily
 IPR033139  Peptidase family C14A, cysteine active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0030855 epithelial cell differentiation IEA
 biological_processGO:0072734 cellular response to staurosporine IEA
 biological_processGO:0097194 execution phase of apoptosis IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0004175 endopeptidase activity IEA
 molecular_functionGO:0004197 cysteine-type endopeptidase activity IEA
 molecular_functionGO:0008234 cysteine-type peptidase activity IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0097153 cysteine-type endopeptidase activity involved in apoptotic process IBA
 molecular_functionGO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis IEA


Pathways (from Reactome)
Pathway description
Apoptotic cleavage of cellular proteins
Caspase-mediated cleavage of cytoskeletal proteins
Breakdown of the nuclear lamina


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr