ENSGALG00000046494


Gallus gallus

Features
Gene ID: ENSGALG00000046494
  
Biological name :CASP10
  
Synonyms : CASP10 / caspase 10
  
Possible biological names infered from orthology : Q92851
  
Species: Gallus gallus
  
Chr. number: 7
Strand: 1
Band:
Gene start: 11477412
Gene end: 11485621
  
Corresponding Affymetrix probe sets: GgaAffx.5246.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000061174
Ensembl peptide - ENSGALP00000062992
NCBI entrez gene - 424081     See in Manteia.
RefSeq - XM_421936
RefSeq - XM_004942610
swissprot - A0A1L1RVX4
swissprot - A0A1L1RQV3
Ensembl - ENSGALG00000046494
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 casp8l2ENSDARG00000070272Danio rerio
 CASP10ENSG00000003400Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CASP8 / caspase-8 / O89110* / Q14790* / Caspase-8 Caspase-8 subunit p18 Caspase-8 subunit p10*ENSGALG0000000835535
CASP18ENSGALG0000000834633
CASP2 / caspase-2 / P29594* / P42575* / Caspase-2 Caspase-2 subunit p18 Caspase-2 subunit p13 Caspase-2 subunit p12*ENSGALG0000001469820
CASP9 / caspase 9 / P55211* / Q8C3Q9* / Mus musculus caspase 9 (Casp9), transcript variant 3, mRNA.*ENSGALG0000000136619
CASP3 / caspase 3 / P42574* / P70677* / Caspase-3 Caspase-3 subunit p17 Caspase-3 subunit p12*ENSGALG0000001063818
CASP6 / caspase-6 / O08738* / P55212* / Caspase-6 Caspase-6 subunit p18 Caspase-6 subunit p11*ENSGALG0000001218617
CASP7 / caspase 7 / P55210* / P97864* / Caspase-7 Caspase-7 subunit p20 Caspase-7 subunit p11*ENSGALG0000000893317


Protein motifs (from Interpro)
Interpro ID Name
 IPR001309  Peptidase C14, p20 domain
 IPR001875  Death effector domain
 IPR002138  Peptidase C14, caspase non-catalytic subunit p10
 IPR011029  Death-like domain superfamily
 IPR015917  Peptidase C14A, caspase catalytic domain
 IPR016129  Peptidase family C14A, His active site
 IPR029030  Caspase-like domain superfamily
 IPR033139  Peptidase family C14A, cysteine active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0042981 regulation of apoptotic process IEA
 biological_processGO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling IEA
 biological_processGO:0097190 apoptotic signaling pathway IEA
 cellular_componentGO:0031265 CD95 death-inducing signaling complex IEA
 cellular_componentGO:0097342 ripoptosome IEA
 molecular_functionGO:0004197 cysteine-type endopeptidase activity IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008234 cysteine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IEA
 molecular_functionGO:0035877 death effector domain binding IEA
 molecular_functionGO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway IEA


Pathways (from Reactome)
Pathway description
FasL/ CD95L signaling
TRAIL signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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