ENSGALG00000009681


Gallus gallus

Features
Gene ID: ENSGALG00000009681
  
Biological name :BUB3
  
Synonyms : BUB3 / BUB3, mitotic checkpoint protein
  
Possible biological names infered from orthology : Mitotic checkpoint protein BUB3 / O43684 / Q9WVA3
  
Species: Gallus gallus
  
Chr. number: 6
Strand: 1
Band:
Gene start: 31536692
Gene end: 31548248
  
Corresponding Affymetrix probe sets: GgaAffx.13124.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000061487
Ensembl peptide - ENSGALP00000015741
Ensembl peptide - ENSGALP00000048690
NCBI entrez gene - 423949     See in Manteia.
RefSeq - XM_015288690
RefSeq - NM_001006506
RefSeq - XM_015288687
RefSeq - XM_015288688
RefSeq - XM_015288689
RefSeq - XM_015288686
RefSeq Peptide - NP_001006506
swissprot - Q5ZHW3
swissprot - A0A1D5P7J9
Ensembl - ENSGALG00000009681
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 bub3ENSDARG00000075883Danio rerio
 BUB3ENSG00000154473Homo sapiens
 Bub3ENSMUSG00000066979Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RAE1 / ribonucleic acid export 1 / P78406* / Q8C570* / mRNA export factor *ENSGALG0000000765336


Protein motifs (from Interpro)
Interpro ID Name
 IPR001680  WD40 repeat
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017986  WD40-repeat-containing domain
 IPR020472  G-protein beta WD-40 repeat


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000070 mitotic sister chromatid segregation IEA
 biological_processGO:0007059 chromosome segregation IEA
 biological_processGO:0008608 attachment of spindle microtubules to kinetochore IEA
 biological_processGO:0051983 regulation of chromosome segregation IEA
 cellular_componentGO:0000776 kinetochore IEA
 cellular_componentGO:0005654 nucleoplasm IEA


Pathways (from Reactome)
Pathway description
Inactivation of APC/C via direct inhibition of the APC/C complex
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Cdc20:Phospho-APC/C mediated degradation of Cyclin A
APC/C:Cdc20 mediated degradation of mitotic proteins
APC-Cdc20 mediated degradation of Nek2A
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
RHO GTPases Activate Formins
Mitotic Prometaphase


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000003085 CDK1 / cyclin-dependent kinase 1 / P06493* / P11440*  / reaction / complex
 ENSGALG00000009971 CDC20 / cell division cycle 20 / Q12834* / Q9JJ66* / Cell division cycle *  / complex / reaction
 ENSGALG00000036790 P79781 / RPS27A / Ubiquitin-40S ribosomal protein S27a Ubiquitin 40S ribosomal protein S27a / P62983* / P62979* / AL136454.1* / ribosomal protein S27a*  / complex / reaction
 ENSGALG00000037716 UBA52 / ubiquitin A-52 residue ribosomal protein fusion product 1 / P62984* / P62987* / Gm5239* / Gm11808* / predicted gene 11808*  / complex / reaction
 ENSGALG00000036892 BUB1B / BUB1 mitotic checkpoint serine/threonine kinase B / O60566* / Q9Z1S0* / Mitotic checkpoint serine/threonine-protein kinase BUB1 beta *  / reaction / complex






 

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