ENSGALG00000013793


Gallus gallus

Features
Gene ID: ENSGALG00000013793
  
Biological name :CLOCK
  
Synonyms : circadian locomoter output cycles protein kaput isoform 1 / CLOCK
  
Possible biological names infered from orthology : Circadian locomoter output cycles protein kaput / clock circadian regulator / O08785 / O15516
  
Species: Gallus gallus
  
Chr. number: 4
Strand: 1
Band:
Gene start: 65497092
Gene end: 65522295
  
Corresponding Affymetrix probe sets: Gga.2707.2.S1_a_at (Chicken Array)   Gga.2707.3.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000036747
Ensembl peptide - ENSGALP00000036748
NCBI entrez gene - 373991     See in Manteia.
RefSeq - XM_015285400
RefSeq - XM_015285396
RefSeq - XM_015285397
RefSeq - XM_015285398
RefSeq - XM_015285399
RefSeq - NM_001289834
RefSeq - NM_204174
RefSeq - XM_015285392
RefSeq - XM_015285393
RefSeq - XM_015285394
RefSeq Peptide - NP_989505
RefSeq Peptide - NP_001276763
swissprot - F1NKI9
swissprot - F1NKI8
Ensembl - ENSGALG00000013793
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 clockaENSDARG00000011703Danio rerio
 clockbENSDARG00000003631Danio rerio
 CLOCKENSG00000134852Homo sapiens
 ClockENSMUSG00000029238Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NPAS2 / neuronal PAS domain-containing protein 2 / Q99743* / neuronal PAS domain protein 2*ENSGALG0000001677447
ENSGALG0000000906341
ARNT / aryl hydrocarbon receptor nuclear translocator / P27540* / P53762*ENSGALG0000000075118
ARNTL2 / aryl hydrocarbon receptor nuclear translocator-like protein 2 / Q2VPD4* / Q8WYA1* / aryl hydrocarbon receptor nuclear translocator like 2*ENSGALG0000001409616
EPAS1 / endothelial PAS domain protein 1 / P97481* / Q99814* / Endothelial PAS domain-containing protein 1 *ENSGALG0000001000516
HIF1A / hypoxia-inducible factor 1-alpha / Q16665* / Q61221* / hypoxia inducible factor 1 alpha subunit*ENSGALG0000001187016
ARNT2 / aryl hydrocarbon receptor nuclear translocator 2 / Q61324* / Q9HBZ2*ENSGALG0000000644516
ARNTL / Q9I8T7 / Aryl hydrocarbon receptor nuclear translocator-like protein 1 / Q9WTL8* / O00327* / aryl hydrocarbon receptor nuclear translocator like* / Mus musculus aryl hydrocarbon re...ENSGALG0000000537816
NPAS3 / neuronal PAS domain protein 3 / Q8IXF0*ENSGALG0000002902212
SIM2 / single-minded family bHLH transcription factor 2 / Q14190* / Q61079* / Single-minded homolog 2 *ENSGALG0000001604412
SIM1 / single-minded family bHLH transcription factor 1 / P81133* / Q61045* / Single-minded homolog 1 *ENSGALG0000001546611


Protein motifs (from Interpro)
Interpro ID Name
 IPR000014  PAS domain
 IPR001067  Nuclear translocator
 IPR001610  PAC motif
 IPR011598  Myc-type, basic helix-loop-helix (bHLH) domain
 IPR013767  PAS fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000077 DNA damage checkpoint IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0006473 protein acetylation IEA
 biological_processGO:0007283 spermatogenesis IEA
 biological_processGO:0007623 circadian rhythm IEA
 biological_processGO:0016573 histone acetylation IEA
 biological_processGO:0032922 circadian regulation of gene expression IEA
 biological_processGO:0042634 regulation of hair cycle IEA
 biological_processGO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0050729 positive regulation of inflammatory response IEA
 biological_processGO:0050796 regulation of insulin secretion IEA
 biological_processGO:0051092 positive regulation of NF-kappaB transcription factor activity IEA
 biological_processGO:0051775 response to redox state IEA
 biological_processGO:0071479 cellular response to ionizing radiation IEA
 biological_processGO:2000074 regulation of type B pancreatic cell development IEA
 biological_processGO:2000323 negative regulation of glucocorticoid receptor signaling pathway IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005667 transcription factor complex IEA
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0033391 chromatoid body IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0000982 transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0001046 core promoter sequence-specific DNA binding IEA
 molecular_functionGO:0001047 core promoter binding IEA
 molecular_functionGO:0001190 transcriptional activator activity, RNA polymerase II transcription factor binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0004402 histone acetyltransferase activity IEA
 molecular_functionGO:0031490 chromatin DNA binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0046983 protein dimerization activity IEA
 molecular_functionGO:0070888 E-box binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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