ENSGALG00000014638


Gallus gallus

Features
Gene ID: ENSGALG00000014638
  
Biological name :ASH1L
  
Synonyms : ASH1L / ASH1 like histone lysine methyltransferase
  
Possible biological names infered from orthology : Histone-lysine N-methyltransferase ASH1L / Q99MY8 / Q9NR48
  
Species: Gallus gallus
  
Chr. number: 25
Strand: -1
Band:
Gene start: 2206557
Gene end: 2239618
  
Corresponding Affymetrix probe sets: Gga.18938.1.S1_at (Chicken Array)   GgaAffx.24475.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000023545
NCBI entrez gene - 425064     See in Manteia.
RefSeq - XM_015298652
RefSeq - XM_015298653
RefSeq - XM_015298654
swissprot - H9L0M3
Ensembl - ENSGALG00000014638
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ash1lENSDARG00000070981Danio rerio
 ASH1LENSG00000116539Homo sapiens
 Ash1lENSMUSG00000028053Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SETD2 / SET domain containing 2 / E9Q5F9* / Q9BYW2* / Histone-lysine N-methyltransferase SETD2 *ENSGALG0000004205113
NSD1 / nuclear receptor binding SET domain protein 1 / Q96L73*ENSGALG000000029718
NSD2 / nuclear receptor binding SET domain protein 2 / O96028* / Q8BVE8* / Histone-lysine N-methyltransferase NSD2 *ENSGALG000000157058
NSD3 / nuclear receptor binding SET domain protein 3 / Q6P2L6* / Q9BZ95* / Histone-lysine N-methyltransferase NSD3 *ENSGALG000000032997
SETBP1 / SET binding protein 1 / Q9Y6X0* / Q9Z180* / SET-binding protein *ENSGALG000000367756
EHMT1 / histone-lysine N-methyltransferase EHMT1 / Q5DW34* / Q9H9B1* / euchromatic histone lysine methyltransferase 1*ENSGALG000000336785
EZH1 / enhancer of zeste 1 polycomb repressive complex 2 subunit / P70351* / Q92800* / Histone-lysine N-methyltransferase EZH1 *ENSGALG000000030684
SETDB1 / SET domain bifurcated 1 / Q15047*ENSGALG000000240514
EZH2 / enhancer of zeste 2 polycomb repressive complex 2 subunit / Q15910* / Q61188* / Histone-lysine N-methyltransferase EZH2 *ENSGALG000000433994
Q5F3W5 / SUV39H2 / Histone-lysine N-methyltransferase SUV39H2 / Q9H5I1* / suppressor of variegation 3-9 2* / suppressor of variegation 3-9 homolog 2*ENSGALG000000139203
SETDB2 / SET domain bifurcated 2 / Q8C267* / Q96T68*ENSGALG000000170062


Protein motifs (from Interpro)
Interpro ID Name
 IPR001025  Bromo adjacent homology (BAH) domain
 IPR001214  SET domain
 IPR001487  Bromodomain
 IPR001965  Zinc finger, PHD-type
 IPR003616  Post-SET domain
 IPR006560  AWS domain
 IPR011011  Zinc finger, FYVE/PHD-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR017956  AT hook, DNA-binding motif
 IPR019786  Zinc finger, PHD-type, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001501 skeletal system development IEA
 biological_processGO:0002674 negative regulation of acute inflammatory response IEA
 biological_processGO:0007338 single fertilization IEA
 biological_processGO:0009791 post-embryonic development IEA
 biological_processGO:0010468 regulation of gene expression IEA
 biological_processGO:0032259 methylation IEA
 biological_processGO:0032635 interleukin-6 production IEA
 biological_processGO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling IEA
 biological_processGO:0043409 negative regulation of MAPK cascade IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0046697 decidualization IEA
 biological_processGO:0048733 sebaceous gland development IEA
 biological_processGO:0050728 negative regulation of inflammatory response IEA
 biological_processGO:0051568 histone H3-K4 methylation IEA
 biological_processGO:0061038 uterus morphogenesis IEA
 biological_processGO:0097676 histone H3-K36 dimethylation IEA
 biological_processGO:0097722 sperm motility IEA
 biological_processGO:1903699 tarsal gland development IEA
 biological_processGO:1903709 uterine gland development IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003682 chromatin binding IEA
 molecular_functionGO:0008168 methyltransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0018024 histone-lysine N-methyltransferase activity IEA
 molecular_functionGO:0042800 histone methyltransferase activity (H3-K4 specific) IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0046975 histone methyltransferase activity (H3-K36 specific) IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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