ENSGALG00000002971


Gallus gallus

Features
Gene ID: ENSGALG00000002971
  
Biological name :NSD1
  
Synonyms : NSD1 / nuclear receptor binding SET domain protein 1
  
Possible biological names infered from orthology : Q96L73
  
Species: Gallus gallus
  
Chr. number: 13
Strand: -1
Band:
Gene start: 10206726
Gene end: 10259504
  
Corresponding Affymetrix probe sets: Gga.17917.1.S1_at (Chicken Array)   Gga.17917.1.S1_s_at (Chicken Array)   Gga.7535.1.S1_at (Chicken Array)   GgaAffx.1898.1.S1_at (Chicken Array)   GgaAffx.25698.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000004690
Ensembl peptide - ENSGALP00000053156
Ensembl peptide - ENSGALP00000049057
NCBI entrez gene - 416214     See in Manteia.
RefSeq - XM_015293828
swissprot - A0A1D5PK07
swissprot - A0A1D5P8K9
swissprot - F1N972
Ensembl - ENSGALG00000002971
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nsd1aENSDARG00000060016Danio rerio
 nsd1bENSDARG00000060705Danio rerio
 NSD1ENSG00000165671Homo sapiens
 Nsd1ENSMUSG00000021488Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NSD2 / nuclear receptor binding SET domain protein 2 / O96028* / Q8BVE8* / Histone-lysine N-methyltransferase NSD2 *ENSGALG0000001570521
NSD3 / nuclear receptor binding SET domain protein 3 / Q6P2L6* / Q9BZ95* / Histone-lysine N-methyltransferase NSD3 *ENSGALG0000000329919
SETD2 / SET domain containing 2 / E9Q5F9* / Q9BYW2* / Histone-lysine N-methyltransferase SETD2 *ENSGALG000000420518
ASH1L / ASH1 like histone lysine methyltransferase / Q99MY8* / Q9NR48* / Histone-lysine N-methyltransferase ASH1L *ENSGALG000000146388
EHMT1 / histone-lysine N-methyltransferase EHMT1 / Q5DW34* / Q9H9B1* / euchromatic histone lysine methyltransferase 1*ENSGALG000000336786
SETDB1 / SET domain bifurcated 1 / Q15047*ENSGALG000000240515
SETBP1 / SET binding protein 1 / Q9Y6X0* / Q9Z180* / SET-binding protein *ENSGALG000000367755
EZH2 / enhancer of zeste 2 polycomb repressive complex 2 subunit / Q15910* / Q61188* / Histone-lysine N-methyltransferase EZH2 *ENSGALG000000433994
EZH1 / enhancer of zeste 1 polycomb repressive complex 2 subunit / P70351* / Q92800* / Histone-lysine N-methyltransferase EZH1 *ENSGALG000000030684
Q5F3W5 / SUV39H2 / Histone-lysine N-methyltransferase SUV39H2 / Q9H5I1* / suppressor of variegation 3-9 2* / suppressor of variegation 3-9 homolog 2*ENSGALG000000139203
SETDB2 / SET domain bifurcated 2 / Q8C267* / Q96T68*ENSGALG000000170063


Protein motifs (from Interpro)
Interpro ID Name
 IPR000313  PWWP domain
 IPR001214  SET domain
 IPR001965  Zinc finger, PHD-type
 IPR003616  Post-SET domain
 IPR006560  AWS domain
 IPR011011  Zinc finger, FYVE/PHD-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR019786  Zinc finger, PHD-type, conserved site
 IPR019787  Zinc finger, PHD-finger


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000414 regulation of histone H3-K36 methylation IEA
 biological_processGO:0010452 histone H3-K36 methylation IEA
 biological_processGO:0032259 methylation IEA
 biological_processGO:0033135 regulation of peptidyl-serine phosphorylation IEA
 biological_processGO:0034968 histone lysine methylation IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0003712 transcription coregulator activity IEA
 molecular_functionGO:0008168 methyltransferase activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0018024 histone-lysine N-methyltransferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0046975 histone methyltransferase activity (H3-K36 specific) IEA
 molecular_functionGO:0050681 androgen receptor binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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