ENSGALG00000042051


Gallus gallus

Features
Gene ID: ENSGALG00000042051
  
Biological name :SETD2
  
Synonyms : SETD2 / SET domain containing 2
  
Possible biological names infered from orthology : E9Q5F9 / Histone-lysine N-methyltransferase SETD2 / Q9BYW2
  
Species: Gallus gallus
  
Chr. number: 2
Strand: -1
Band:
Gene start: 3915871
Gene end: 3953545
  
Corresponding Affymetrix probe sets: Gga.10543.1.S1_at (Chicken Array)   Gga.10543.1.S1_s_at (Chicken Array)   Gga.12794.1.S1_at (Chicken Array)   Gga.8189.1.S1_at (Chicken Array)   GgaAffx.26513.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000044847
NCBI entrez gene - 420404     See in Manteia.
RefSeq - XM_015281125
swissprot - A0A1D5NWV4
Ensembl - ENSGALG00000042051
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 setd2ENSDARG00000062244Danio rerio
 SETD2ENSG00000181555Homo sapiens
 Setd2ENSMUSG00000044791Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ASH1L / ASH1 like histone lysine methyltransferase / Q99MY8* / Q9NR48* / Histone-lysine N-methyltransferase ASH1L *ENSGALG0000001463816
NSD1 / nuclear receptor binding SET domain protein 1 / Q96L73*ENSGALG000000029719
NSD3 / nuclear receptor binding SET domain protein 3 / Q6P2L6* / Q9BZ95* / Histone-lysine N-methyltransferase NSD3 *ENSGALG000000032999
NSD2 / nuclear receptor binding SET domain protein 2 / O96028* / Q8BVE8* / Histone-lysine N-methyltransferase NSD2 *ENSGALG000000157059
EHMT1 / histone-lysine N-methyltransferase EHMT1 / Q5DW34* / Q9H9B1* / euchromatic histone lysine methyltransferase 1*ENSGALG000000336787
SETBP1 / SET binding protein 1 / Q9Y6X0* / Q9Z180* / SET-binding protein *ENSGALG000000367756
SETDB1 / SET domain bifurcated 1 / Q15047*ENSGALG000000240515
Q5F3W5 / SUV39H2 / Histone-lysine N-methyltransferase SUV39H2 / Q9H5I1* / suppressor of variegation 3-9 2* / suppressor of variegation 3-9 homolog 2*ENSGALG000000139204
EZH2 / enhancer of zeste 2 polycomb repressive complex 2 subunit / Q15910* / Q61188* / Histone-lysine N-methyltransferase EZH2 *ENSGALG000000433994
EZH1 / enhancer of zeste 1 polycomb repressive complex 2 subunit / P70351* / Q92800* / Histone-lysine N-methyltransferase EZH1 *ENSGALG000000030684
SETDB2 / SET domain bifurcated 2 / Q8C267* / Q96T68*ENSGALG000000170064


Protein motifs (from Interpro)
Interpro ID Name
 IPR001202  WW domain
 IPR001214  SET domain
 IPR003616  Post-SET domain
 IPR006560  AWS domain
 IPR013257  Set2 Rpb1 interacting domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis IEA
 biological_processGO:0001570 vasculogenesis IEA
 biological_processGO:0001763 morphogenesis of a branching structure IEA
 biological_processGO:0001843 neural tube closure IEA
 biological_processGO:0006298 mismatch repair IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006368 transcription elongation from RNA polymerase II promoter IEA
 biological_processGO:0010452 histone H3-K36 methylation IEA
 biological_processGO:0010468 regulation of gene expression IEA
 biological_processGO:0010569 regulation of double-strand break repair via homologous recombination IEA
 biological_processGO:0010793 regulation of mRNA export from nucleus IEA
 biological_processGO:0018023 peptidyl-lysine trimethylation IEA
 biological_processGO:0018026 peptidyl-lysine monomethylation IEA
 biological_processGO:0030900 forebrain development IEA
 biological_processGO:0032259 methylation IEA
 biological_processGO:0032465 regulation of cytokinesis IEA
 biological_processGO:0032727 positive regulation of interferon-alpha production IEA
 biological_processGO:0034340 response to type I interferon IEA
 biological_processGO:0034728 nucleosome organization IEA
 biological_processGO:0034968 histone lysine methylation IEA
 biological_processGO:0035441 cell migration involved in vasculogenesis IEA
 biological_processGO:0035987 endodermal cell differentiation IEA
 biological_processGO:0048332 mesoderm morphogenesis IEA
 biological_processGO:0048568 embryonic organ development IEA
 biological_processGO:0048701 embryonic cranial skeleton morphogenesis IEA
 biological_processGO:0048863 stem cell differentiation IEA
 biological_processGO:0048864 stem cell development IEA
 biological_processGO:0051607 defense response to virus IEA
 biological_processGO:0060039 pericardium development IEA
 biological_processGO:0060669 embryonic placenta morphogenesis IEA
 biological_processGO:0060977 coronary vasculature morphogenesis IEA
 biological_processGO:0097198 histone H3-K36 trimethylation IEA
 biological_processGO:0097676 histone H3-K36 dimethylation IEA
 biological_processGO:1902850 microtubule cytoskeleton organization involved in mitosis IEA
 biological_processGO:1905634 regulation of protein localization to chromatin IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005694 chromosome IEA
 molecular_functionGO:0008168 methyltransferase activity IEA
 molecular_functionGO:0016279 protein-lysine N-methyltransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0018024 histone-lysine N-methyltransferase activity IEA
 molecular_functionGO:0043014 alpha-tubulin binding IEA
 molecular_functionGO:0046975 histone methyltransferase activity (H3-K36 specific) IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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