ENSGALG00000016420


Gallus gallus

Features
Gene ID: ENSGALG00000016420
  
Biological name :SH3KBP1
  
Synonyms : SH3 domain containing kinase binding protein 1 / SH3KBP1
  
Possible biological names infered from orthology : Q8R550 / Q96B97
  
Species: Gallus gallus
  
Chr. number: 1
Strand: 1
Band:
Gene start: 119981518
Gene end: 120203381
  
Corresponding Affymetrix probe sets: Gga.3379.1.S1_at (Chicken Array)   Gga.3379.2.S1_at (Chicken Array)   Gga.3379.3.S1_at (Chicken Array)   Gga.3379.3.S1_s_at (Chicken Array)   GgaAffx.11430.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000045935
Ensembl peptide - ENSGALP00000053400
Ensembl peptide - ENSGALP00000026438
NCBI entrez gene - 418608     See in Manteia.
RefSeq - XM_015302547
RefSeq - XM_015302523
RefSeq - XM_015302527
RefSeq - XM_015302533
RefSeq - XM_015302540
RefSeq - NM_001030805
RefSeq - XM_015302491
RefSeq - XM_015302495
RefSeq - XM_015302501
RefSeq - XM_015302505
RefSeq - XM_015302511
RefSeq - XM_015302517
RefSeq Peptide - NP_001025976
swissprot - A0A1D5PKN9
swissprot - A0A1D5NZW5
swissprot - Q5ZMQ7
Ensembl - ENSGALG00000016420
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sh3kbp1ENSDARG00000075853Danio rerio
 Q96B97ENSG00000147010Homo sapiens
 Q8R550ENSMUSG00000040990Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CD2AP / Gallus gallus CD2 associated protein (CD2AP), mRNA. / Q9JLQ0* / Q9Y5K6* / CD2 associated protein*ENSGALG0000001672031


Protein motifs (from Interpro)
Interpro ID Name
 IPR001452  SH3 domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007010 cytoskeleton organization IEA
 biological_processGO:0008360 regulation of cell shape IEA
 biological_processGO:0016477 cell migration IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005911 cell-cell junction IEA
 cellular_componentGO:0030139 endocytic vesicle IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
EGFR downregulation
Negative regulation of MET activity
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis
Reelin signalling pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000008016 GRB2 / growth factor receptor-bound protein 2 / P62993* / Q60631*  / complex / reaction
 ENSGALG00000007224 HGS / hepatocyte growth factor-regulated tyrosine kinase substrate / O14964* / hepatocyte growth factor-regulated tyrosine kinase substrate isoform 2 *  / complex / reaction
 ENSGALG00000010166 VLDLR / P98165 / Very low-density lipoprotein receptor / P98155* / P98156*  / complex / reaction
 ENSGALG00000016420 SH3KBP1 / SH3 domain containing kinase binding protein 1 / Q8R550* / Q96B97*  / complex
 ENSGALG00000038089 EGFR / epidermal growth factor receptor / P00533* / Q01279*  / reaction
 ENSGALG00000015096 Q8AXV1 / SH3GL2 / Endophilin-A1 / Q99962* / Q62420* / SH3-domain GRB2-like 2* / SH3 domain containing GRB2 like 2, endophilin A1*  / complex
 ENSGALG00000010857 DAB1 / disabled homolog 1 / O75553* / P97318* / DAB1, reelin adaptor protein*  / reaction / complex
 ENSGALG00000010543 EPS15 / epidermal growth factor receptor substrate 15 / P42566* / P42567* / epidermal growth factor receptor pathway substrate 15*  / reaction / complex
 ENSGALG00000015022 FYN / tyrosine-protein kinase Fyn / P06241* / P39688* / FYN proto-oncogene, Src family tyrosine kinase*  / reaction
 ENSGALG00000036883 MET / hepatocyte growth factor receptor precursor / P08581* / MET proto-oncogene, receptor tyrosine kinase*  / complex / reaction
 ENSGALG00000035287 STAM / signal transducing adaptor molecule / P70297* / Q92783* / signal transducing adaptor molecule (SH3 domain and ITAM motif) 1*  / complex / reaction
 ENSGALG00000033974 HGF / hepatocyte growth factor / P14210* / Q08048* / Hepatocyte growth factor Hepatocyte growth factor alpha chain Hepatocyte growth factor beta chain*  / reaction / complex






 

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