ENSGALG00000030030


Gallus gallus

Features
Gene ID: ENSGALG00000030030
  
Biological name :RSPO2
  
Synonyms : RSPO2 / R-spondin-2 precursor
  
Possible biological names infered from orthology : Mus musculus R-spondin 2 (Rspo2), transcript variant 1, mRNA. / Q6UXX9 / Q8BFU0 / R-spondin 2
  
Species: Gallus gallus
  
Chr. number: 2
Strand: -1
Band:
Gene start: 132121027
Gene end: 132231350
  
Corresponding Affymetrix probe sets: GgaAffx.10260.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000053995
Ensembl peptide - ENSGALP00000052961
NCBI entrez gene - 420271     See in Manteia.
RefSeq - XM_015283018
RefSeq Peptide - NP_001305953
swissprot - I0IVW2
swissprot - A0A1D5PMB9
Ensembl - ENSGALG00000030030
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rspo2ENSDARG00000079570Danio rerio
 RSPO2ENSG00000147655Homo sapiens
 Rspo2ENSMUSG00000051920Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RSPO3 / Gallus gallus R-spondin 3 (RSPO3), mRNA. / Q2TJ95* / Q9BXY4* / R-spondin 3*ENSGALG0000004260743
RSPO1 / R-spondin-1 precursor / Q2MKA7* / R-spondin 1*ENSGALG0000000194641
RSPO4 / R-spondin 4 / Q2I0M5* / Q8BJ73*ENSGALG0000002364040


Protein motifs (from Interpro)
Interpro ID Name
 IPR000884  Thrombospondin type-1 (TSP1) repeat
 IPR006212  Furin-like repeat
 IPR009030  Growth factor receptor cysteine-rich domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001649 osteoblast differentiation IEA
 biological_processGO:0030282 bone mineralization IEA
 biological_processGO:0035115 embryonic forelimb morphogenesis IEA
 biological_processGO:0035116 embryonic hindlimb morphogenesis IEA
 biological_processGO:0042489 negative regulation of odontogenesis of dentin-containing tooth IEA
 biological_processGO:0060437 lung growth IEA
 biological_processGO:0060441 epithelial tube branching involved in lung morphogenesis IEA
 biological_processGO:0060535 trachea cartilage morphogenesis IEA
 biological_processGO:0071542 dopaminergic neuron differentiation IEA
 biological_processGO:0090263 positive regulation of canonical Wnt signaling pathway IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0009986 cell surface IEA
 molecular_functionGO:0005102 signaling receptor binding IEA
 molecular_functionGO:0008201 heparin binding IEA


Pathways (from Reactome)
Pathway description
Regulation of FZD by ubiquitination


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000001028 RNF43 / ring finger protein 43 / Q5NCP0* / Q68DV7* / E3 ubiquitin-protein ligase RNF43 *  / complex / reaction
 ENSGALG00000010163 LGR5 / leucine rich repeat containing G protein-coupled receptor 5 / O75473* / Q9Z1P4*  / reaction / complex
 ENSGALG00000036790 P79781 / RPS27A / Ubiquitin-40S ribosomal protein S27a Ubiquitin 40S ribosomal protein S27a / P62983* / P62979* / AL136454.1* / ribosomal protein S27a*  / reaction
 ENSGALG00000037716 UBA52 / ubiquitin A-52 residue ribosomal protein fusion product 1 / P62984* / P62987* / Gm5239* / Gm11808* / predicted gene 11808*  / reaction
 ENSGALG00000040834 LGR4 / leucine rich repeat containing G protein-coupled receptor 4 / A2ARI4* / Q9BXB1*  / reaction / complex






 

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