ENSGALG00000001028


Gallus gallus

Features
Gene ID: ENSGALG00000001028
  
Biological name :RNF43
  
Synonyms : ring finger protein 43 / RNF43
  
Possible biological names infered from orthology : E3 ubiquitin-protein ligase RNF43 / Q5NCP0 / Q68DV7
  
Species: Gallus gallus
  
Chr. number: 19
Strand: -1
Band:
Gene start: 527581
Gene end: 580075
  
Corresponding Affymetrix probe sets: GgaAffx.663.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000001522
Ensembl peptide - ENSGALP00000051908
NCBI entrez gene - 100857874     See in Manteia.
RefSeq - XM_003642379
swissprot - A0A1D5PGI6
swissprot - E1BQX5
Ensembl - ENSGALG00000001028
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RNF43ENSG00000108375Homo sapiens
 Rnf43ENSMUSG00000034177Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ZNRF3* / Q5SSZ7* / Q9ULT6* / zinc and ring finger 3*ENSGALG0000000580316
RNF13 / Q90972 / E3 ubiquitin-protein ligase RNF13 / O54965* / O43567* / ring finger protein 13*ENSGALG0000001041110
RNF148* / Q8TEB7* / Q8WVZ7* / Q9D304* / RNF128* / RNF133* / G3X9R7* / Q14B02* / Q8N7C7* / ring finger protein 148* / ring finger protein 133* / E3 ubiquitin-protein ligase RNF133 * / E3 ubi...ENSGALG000000419778
RNF150 / ring finger protein 150 / Q5DTZ6* / Q9ULK6*ENSGALG000000098658
RNF215 / ring finger protein 215 / Q5SPX3* / Q9Y6U7*ENSGALG000000409258
RNF130 / ring finger protein 130 / Q86XS8* / Q8VEM1*ENSGALG000000058208
RNF149 / ring finger protein 149 / Q3U2C5* / Q8NC42* / E3 ubiquitin-protein ligase RNF149 *ENSGALG000000167797
ZNRF3* / Q5SSZ7* / Q9ULT6* / zinc and ring finger 3*ENSGALG000000388616
ZNRF4* / Q8WWF5* / Q9DAH2* / zinc and ring finger 4*ENSGALG000000381646


Protein motifs (from Interpro)
Interpro ID Name
 IPR001841  Zinc finger, RING-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR024766  Zinc finger, RING-H2-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0030178 negative regulation of Wnt signaling pathway IEA
 biological_processGO:0038018 Wnt receptor catabolic process IEA
 biological_processGO:0072089 stem cell proliferation IEA
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IEA
 molecular_functionGO:0005109 frizzled binding IEA
 molecular_functionGO:0008270 zinc ion binding IEA


Pathways (from Reactome)
Pathway description
Regulation of FZD by ubiquitination


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000036790 P79781 / RPS27A / Ubiquitin-40S ribosomal protein S27a Ubiquitin 40S ribosomal protein S27a / P62983* / P62979* / AL136454.1* / ribosomal protein S27a*  / reaction
 ENSGALG00000037716 UBA52 / ubiquitin A-52 residue ribosomal protein fusion product 1 / P62984* / P62987* / Gm5239* / Gm11808* / predicted gene 11808*  / reaction
 ENSGALG00000010163 LGR5 / leucine rich repeat containing G protein-coupled receptor 5 / O75473* / Q9Z1P4*  / complex / reaction
 ENSGALG00000001946 RSPO1 / R-spondin-1 precursor / Q2MKA7* / R-spondin 1*  / complex / reaction
 ENSGALG00000030030 RSPO2 / R-spondin-2 precursor / Q8BFU0* / Q6UXX9* / R-spondin 2* / Mus musculus R-spondin 2 (Rspo2), transcript variant 1, mRNA.*  / complex / reaction
 ENSGALG00000040834 LGR4 / leucine rich repeat containing G protein-coupled receptor 4 / A2ARI4* / Q9BXB1*  / complex / reaction
 ENSGALG00000017242 FZD4 / Q9IA05 / Frizzled-4 / Q61088* / Q9ULV1* / frizzled class receptor 4*  / complex / reaction
 ENSGALG00000031503 LRP6 / LDL receptor related protein 6 / O75581*  / complex / reaction
 ENSGALG00000042657 WNT3A / Q2LMP1 / Protein Wnt-3a / P56704* / P27467* / Wnt family member 3A* / wingless-type MMTV integration site family, member 3A*  / complex / reaction






 

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