ENSGALG00000035576


Gallus gallus

Features
Gene ID: ENSGALG00000035576
  
Biological name :CDK9
  
Synonyms : CDK9 / Cyclin-dependent kinase 9 / Q5ZKN1
  
Possible biological names infered from orthology : P50750 / Q99J95
  
Species: Gallus gallus
  
Chr. number: 17
Strand: -1
Band:
Gene start: 5434507
Gene end: 5441114
  
Corresponding Affymetrix probe sets: GgaAffx.12156.1.S1_at (Chicken Array)   GgaAffx.20538.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000047402
Ensembl peptide - ENSGALP00000047028
NCBI entrez gene - 417226     See in Manteia.
RefSeq - NM_001006201
RefSeq Peptide - NP_001006201
swissprot - Q5ZKN1
swissprot - A0A1D5P3Z6
Ensembl - ENSGALG00000035576
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cdk9ENSDARG00000044811Danio rerio
 CDK9ENSG00000136807Homo sapiens
 Cdk9ENSMUSG00000009555Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CDK12 / cyclin dependent kinase 12 / Q14AX6* / Q9NYV4*ENSGALG0000000173132
CDK13 / cyclin dependent kinase 13 / Q14004* / Q69ZA1*ENSGALG0000004324331


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006282 regulation of DNA repair IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006368 transcription elongation from RNA polymerase II promoter IBA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0031056 regulation of histone modification IEA
 biological_processGO:0031297 replication fork processing IEA
 biological_processGO:0033129 positive regulation of histone phosphorylation IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0051147 regulation of muscle cell differentiation IEA
 biological_processGO:0070816 phosphorylation of RNA polymerase II C-terminal domain IBA
 biological_processGO:0071157 negative regulation of cell cycle arrest IEA
 biological_processGO:0071345 cellular response to cytokine stimulus IEA
 biological_processGO:1900364 negative regulation of mRNA polyadenylation IEA
 biological_processGO:1903839 positive regulation of mRNA 3"-UTR binding IEA
 biological_processGO:2001168 positive regulation of histone H2B ubiquitination IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005694 chromosome IBA
 cellular_componentGO:0008023 transcription elongation factor complex IEA
 cellular_componentGO:0008024 cyclin/CDK positive transcription elongation factor complex IEA
 cellular_componentGO:0016605 PML body IEA
 cellular_componentGO:0036464 cytoplasmic ribonucleoprotein granule IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0001223 transcription coactivator binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003682 chromatin binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0004693 cyclin-dependent protein serine/threonine kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008134 transcription factor binding IBA
 molecular_functionGO:0008353 RNA polymerase II carboxy-terminal domain kinase activity IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0017069 snRNA binding IEA
 molecular_functionGO:0019901 protein kinase binding IEA
 molecular_functionGO:0030332 cyclin binding IBA
 molecular_functionGO:0044212 transcription regulatory region DNA binding IEA
 molecular_functionGO:0097322 7SK snRNA binding IEA


Pathways (from Reactome)
Pathway description
Formation of RNA Pol II elongation complex
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
RNA Polymerase II Pre-transcription Events
TP53 Regulates Transcription of DNA Repair Genes
RNA polymerase II transcribes snRNA genes
RNA Polymerase II Transcription Elongation
Estrogen-dependent gene expression


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000012207 CCNT2 / cyclin T2 / O60583* / Q7TQK0*  / complex / reaction
 ENSGALG00000036001 SMAD2Z / SMAD2* / Q62432* / Q15796* / SMAD family member 2* / Mothers against decapentaplegic homolog 2 *  / reaction
 ENSGALG00000014184 SMAD2* / Q15796* / Q62432* / SMAD family member 2* / Mothers against decapentaplegic homolog 2 *  / reaction
 ENSGALG00000016974 GTF2F2 / general transcription factor IIF subunit 2 / P13984* / Q8R0A0* / ral transcription factor IIF subunit 2 *  / complex






 

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