ENSGALG00000036043


Gallus gallus

Features
Gene ID: ENSGALG00000036043
  
Biological name :TBX3
  
Synonyms : T-box 3 / TBX3
  
Possible biological names infered from orthology : O15119 / P70324
  
Species: Gallus gallus
  
Chr. number: 15
Strand: 1
Band:
Gene start: 12277734
Gene end: 12287707
  
Corresponding Affymetrix probe sets: Gga.963.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000045049
Ensembl peptide - ENSGALP00000059643
NCBI entrez gene - 374202     See in Manteia.
RefSeq - NM_001270878
RefSeq - XM_015294834
RefSeq Peptide - NP_001257807
swissprot - A0A1L1RLL9
swissprot - A0A1D5NXF3
Ensembl - ENSGALG00000036043
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tbx3aENSDARG00000002216Danio rerio
 TBX3ENSG00000135111Homo sapiens
 Tbx3ENSMUSG00000018604Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TBX2 / T-box 2 / Q13207* / Q60707* / T-box transcription factor TBX2 *ENSGALG0000003429756
TBX4 / T-box 4 / P57082* / P70325*ENSGALG0000000528522
TBX5 / Q9PWE8 / T-box transcription factor TBX5 / Q99593* / P70326* / T-box 5*ENSGALG0000000825322
TBX20 / Q8UW76 / T-box transcription factor TBX20 / Q9UMR3* / Q9ES03* / T-box 20*ENSGALG0000003209721
TBX18 / T-box transcription factor TBX18 / O95935* / T-box 18*ENSGALG0000003278920
TBX1 / T-box 1 / O43435*ENSGALG0000004118220
TBX6 / T-box-containing protein TBX6L / O95947* / P70327* / T-box 6* / T-box transcription factor TBX6 *ENSGALG0000000637420
TBX22 / T-box 22 / Q8K402* / Q9Y458*ENSGALG0000000409319
TBX10* / O75333* / Q810F8* / T-box 10* / T-box transcription factor TBX10 *ENSGALG0000003876717
TBX15 / T-box 15 / O70306* / Q96SF7* / T-box transcription factor TBX15 *ENSGALG0000001477613


Protein motifs (from Interpro)
Interpro ID Name
 IPR001699  Transcription factor, T-box
 IPR002070  Transcription factor, Brachyury
 IPR008967  p53-like transcription factor, DNA-binding
 IPR018186  Transcription factor, T-box, conserved site
 IPR022582  Transcription factor, T-box, region of unknown function


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0001501 skeletal system development IEA
 biological_processGO:0001568 blood vessel development IEA
 biological_processGO:0001701 in utero embryonic development IEA
 biological_processGO:0001947 heart looping IEA
 biological_processGO:0003007 heart morphogenesis IEA
 biological_processGO:0003151 outflow tract morphogenesis IEA
 biological_processGO:0003167 atrioventricular bundle cell differentiation IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007569 cell aging IEA
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0008595 anterior/posterior axis specification, embryo IEA
 biological_processGO:0009887 animal organ morphogenesis IEA
 biological_processGO:0010159 specification of animal organ position IEA
 biological_processGO:0019827 stem cell population maintenance IEA
 biological_processGO:0021761 limbic system development IEA
 biological_processGO:0030539 male genitalia development IEA
 biological_processGO:0030540 female genitalia development IEA
 biological_processGO:0030857 negative regulation of epithelial cell differentiation IEA
 biological_processGO:0030879 mammary gland development IEA
 biological_processGO:0032275 luteinizing hormone secretion IEA
 biological_processGO:0035050 embryonic heart tube development IEA
 biological_processGO:0035108 limb morphogenesis IEA
 biological_processGO:0035115 embryonic forelimb morphogenesis IEA
 biological_processGO:0035116 embryonic hindlimb morphogenesis IEA
 biological_processGO:0035136 forelimb morphogenesis IEA
 biological_processGO:0042127 regulation of cell proliferation IEA
 biological_processGO:0042733 embryonic digit morphogenesis IEA
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 biological_processGO:0045662 negative regulation of myoblast differentiation IEA
 biological_processGO:0045787 positive regulation of cell cycle IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0046884 follicle-stimulating hormone secretion IEA
 biological_processGO:0048332 mesoderm morphogenesis IEA
 biological_processGO:0055007 cardiac muscle cell differentiation IEA
 biological_processGO:0060021 roof of mouth development IEA
 biological_processGO:0060412 ventricular septum morphogenesis IEA
 biological_processGO:0060444 branching involved in mammary gland duct morphogenesis IEA
 biological_processGO:0060596 mammary placode formation IEA
 biological_processGO:0060923 cardiac muscle cell fate commitment IEA
 biological_processGO:0060931 sinoatrial node cell development IEA
 biological_processGO:0090398 cellular senescence IEA
 biological_processGO:2000648 positive regulation of stem cell proliferation IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0001078 transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0001085 RNA polymerase II transcription factor binding IEA
 molecular_functionGO:0001102 RNA polymerase II activating transcription factor binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0051087 chaperone binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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