ENSGALG00000034297


Gallus gallus

Features
Gene ID: ENSGALG00000034297
  
Biological name :TBX2
  
Synonyms : T-box 2 / TBX2
  
Possible biological names infered from orthology : Q13207 / Q60707 / T-box transcription factor TBX2
  
Species: Gallus gallus
  
Chr. number: 19
Strand: -1
Band:
Gene start: 7640741
Gene end: 7649750
  
Corresponding Affymetrix probe sets: Gga.18356.1.S1_at (Chicken Array)   Gga.964.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000057931
NCBI entrez gene - 373990     See in Manteia.
RefSeq - XM_001235320
swissprot - A0A1D5PY82
Ensembl - ENSGALG00000034297
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tbx2aENSDARG00000018025Danio rerio
 tbx2bENSDARG00000006120Danio rerio
 TBX2ENSG00000121068Homo sapiens
 Tbx2ENSMUSG00000000093Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TBX3 / T-box 3 / O15119* / P70324*ENSGALG0000003604359
TBX4 / T-box 4 / P57082* / P70325*ENSGALG0000000528524
TBX5 / Q9PWE8 / T-box transcription factor TBX5 / Q99593* / P70326* / T-box 5*ENSGALG0000000825323
TBX20 / Q8UW76 / T-box transcription factor TBX20 / Q9UMR3* / Q9ES03* / T-box 20*ENSGALG0000003209722
TBX18 / T-box transcription factor TBX18 / O95935* / T-box 18*ENSGALG0000003278922
TBX1 / T-box 1 / O43435*ENSGALG0000004118222
TBX6 / T-box-containing protein TBX6L / O95947* / P70327* / T-box 6* / T-box transcription factor TBX6 *ENSGALG0000000637421
TBX22 / T-box 22 / Q8K402* / Q9Y458*ENSGALG0000000409320
TBX10* / O75333* / Q810F8* / T-box 10* / T-box transcription factor TBX10 *ENSGALG0000003876718
TBX15 / T-box 15 / O70306* / Q96SF7* / T-box transcription factor TBX15 *ENSGALG0000001477613


Protein motifs (from Interpro)
Interpro ID Name
 IPR001699  Transcription factor, T-box
 IPR002070  Transcription factor, Brachyury
 IPR008967  p53-like transcription factor, DNA-binding
 IPR018186  Transcription factor, T-box, conserved site
 IPR022582  Transcription factor, T-box, region of unknown function


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0003007 heart morphogenesis IEA
 biological_processGO:0003148 outflow tract septum morphogenesis IEA
 biological_processGO:0003151 outflow tract morphogenesis IEA
 biological_processGO:0003203 endocardial cushion morphogenesis IEA
 biological_processGO:0003256 regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007219 Notch signaling pathway IEA
 biological_processGO:0007521 muscle cell fate determination IEA
 biological_processGO:0007569 cell aging IEA
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0035909 aorta morphogenesis IEA
 biological_processGO:0036302 atrioventricular canal development IEA
 biological_processGO:0042733 embryonic digit morphogenesis IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0048596 embryonic camera-type eye morphogenesis IEA
 biological_processGO:0048738 cardiac muscle tissue development IEA
 biological_processGO:0060021 roof of mouth development IEA
 biological_processGO:0060045 positive regulation of cardiac muscle cell proliferation IEA
 biological_processGO:0060465 pharynx development IEA
 biological_processGO:0060560 developmental growth involved in morphogenesis IEA
 biological_processGO:0060596 mammary placode formation IEA
 biological_processGO:0090398 cellular senescence IEA
 biological_processGO:1901208 negative regulation of heart looping IEA
 biological_processGO:1901211 negative regulation of cardiac chamber formation IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005667 transcription factor complex IEA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0001078 transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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