ENSGALG00000041129


Gallus gallus

Features
Gene ID: ENSGALG00000041129
  
Biological name :TMEM173
  
Synonyms : stimulator of interferon genes protein / TMEM173
  
Possible biological names infered from orthology : Q3TBT3 / Q86WV6 / Stimulator of interferons protein / transmembrane protein 173
  
Species: Gallus gallus
  
Chr. number: 13
Strand: -1
Band:
Gene start: 973493
Gene end: 976440
  
Corresponding Affymetrix probe sets: Gga.6523.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000048751
NCBI entrez gene - 768990     See in Manteia.
RefSeq - XM_015293530
RefSeq - NM_001305152
RefSeq - XM_015293528
RefSeq - XM_015293529
RefSeq - XM_001232170
RefSeq - XM_015293523
RefSeq - XM_015293524
RefSeq - XM_015293525
RefSeq - XM_015293526
RefSeq - XM_015293527
RefSeq Peptide - NP_001292081
swissprot - A0A1D5P7Q9
Ensembl - ENSGALG00000041129
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tmem173ENSDARG00000091058Danio rerio
 Q86WV6ENSG00000184584Homo sapiens
 Q3TBT3ENSMUSG00000024349Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR029158  Stimulator of interferon genes protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002218 activation of innate immune response IEA
 biological_processGO:0002230 positive regulation of defense response to virus by host IEA
 biological_processGO:0032092 positive regulation of protein binding IEA
 biological_processGO:0032481 positive regulation of type I interferon production IEA
 biological_processGO:0032608 interferon-beta production IEA
 biological_processGO:0033160 positive regulation of protein import into nucleus, translocation IEA
 biological_processGO:0035458 cellular response to interferon-beta IEA
 biological_processGO:0042993 obsolete positive regulation of transcription factor import into nucleus IEA
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0051607 defense response to virus IEA
 biological_processGO:0071360 cellular response to exogenous dsRNA IEA
 biological_processGO:0071407 cellular response to organic cyclic compound IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005741 mitochondrial outer membrane IEA
 cellular_componentGO:0005777 peroxisome IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0008134 transcription factor binding IEA
 molecular_functionGO:0019901 protein kinase binding IEA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IEA
 molecular_functionGO:0035438 cyclic-di-GMP binding IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0061507 cyclic-GMP-AMP binding IEA


Pathways (from Reactome)
Pathway description
STING mediated induction of host immune responses
Regulation of innate immune responses to cytosolic DNA
STAT6-mediated induction of chemokines
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000009840 TBK1 / TANK binding kinase 1 / Q9UHD2* / Q9WUN2*  / complex / reaction
 ENSGALG00000034426 TRIM32 / tripartite motif containing 32 / Q13049* / Q8CH72*  / reaction / complex
 ENSGALG00000036790 P79781 / RPS27A / Ubiquitin-40S ribosomal protein S27a Ubiquitin 40S ribosomal protein S27a / P62983* / P62979* / AL136454.1* / ribosomal protein S27a*  / reaction
 ENSGALG00000041129 TMEM173 / stimulator of interferon genes protein / Q86WV6* / Q3TBT3* / transmembrane protein 173* / Stimulator of interferons protein *  / reaction / complex
 ENSGALG00000037716 UBA52 / ubiquitin A-52 residue ribosomal protein fusion product 1 / P62984* / P62987* / Gm5239* / Gm11808* / predicted gene 11808*  / reaction






 

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