ENSGALG00000043460


Gallus gallus

Features
Gene ID: ENSGALG00000043460
  
Biological name :SOX2
  
Synonyms : P48430 / SOX2 / Transcription factor SOX-2
  
Possible biological names infered from orthology : P48431 / SRY-box 2
  
Species: Gallus gallus
  
Chr. number: 9
Strand: -1
Band:
Gene start: 16918111
Gene end: 16919468
  
Corresponding Affymetrix probe sets: Gga.601.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000045318
NCBI entrez gene - 396105     See in Manteia.
RefSeq - NM_205188
RefSeq Peptide - NP_990519
swissprot - A0A1D5NY63
swissprot - P48430
Ensembl - ENSGALG00000043460
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sox2ENSDARG00000070913Danio rerio
 SOX2ENSG00000181449Homo sapiens
 Sox2ENSMUSG00000074637Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SOX1 / transcription factor SOX-1 / O00570* / P53783* / SRY-box 1*ENSGALG0000003035364
SOX14 / Q9W7R6 / Transcription factor SOX-14 / Q04892* / O95416* / SRY-box 14*ENSGALG0000003735233
SOX21 / Q9W7R5 / Transcription factor SOX-21 / Q9Y651* / Q811W0* / SRY-box 21*ENSGALG0000003515733
SOX8 / transcription factor SOX-8 / Q04886* / P57073* / SRY-box 8* / SRY (sex determining region Y)-box 8*ENSGALG0000000526326
SOX10 / Q9W757 / Transcription factor SOX-10 / Q04888* / P56693* / SRY-box 10*ENSGALG0000001229025
SOX17* / Q61473* / Q9H6I2* / SRY-box 17* / Transcription factor SOX-17 *ENSGALG0000003299424
SOX4 / transcription factor SOX-4 / Q06831* / Q06945* / SRY-box 4*ENSGALG0000003649724
SOX17 / transcription factor SOX-17 / Q61473* / Q9H6I2* / SRY-box 17*ENSGALG0000003285124
SOX9 / P48434 / Transcription factor SOX-9 / Q04887* / P48436* / SRY-box 9*ENSGALG0000000438624
SOX18 / transcription factor SOX-18 / P35713* / P43680* / SRY-box 18*ENSGALG0000003411823
SOX7* / Q9BT81* / P40646* / SRY-box 7* / AC105001.2* / SRY (sex determining region Y)-box 7*ENSGALG0000004129622
SOX12 / SRY-box 12 / O15370* / Q04890* / Transcription factor SOX-12 *ENSGALG0000003595120


Protein motifs (from Interpro)
Interpro ID Name
 IPR009071  High mobility group box domain
 IPR022097  Transcription factor SOX
 IPR032643  Transcription factor SOX-2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001649 osteoblast differentiation IEA
 biological_processGO:0001654 eye development IEA
 biological_processGO:0001714 endodermal cell fate specification IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007050 cell cycle arrest IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0009611 response to wounding IEA
 biological_processGO:0010468 regulation of gene expression IEA
 biological_processGO:0016360 sensory organ precursor cell fate determination IMP
 biological_processGO:0021983 pituitary gland development IEA
 biological_processGO:0030900 forebrain development IEA
 biological_processGO:0035019 somatic stem cell population maintenance IEA
 biological_processGO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process IEA
 biological_processGO:0043410 positive regulation of MAPK cascade IEA
 biological_processGO:0045665 negative regulation of neuron differentiation IMP
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IMP
 biological_processGO:0048839 inner ear development IEA
 biological_processGO:0050680 negative regulation of epithelial cell proliferation IEA
 biological_processGO:0070848 response to growth factor IEA
 biological_processGO:0090090 negative regulation of canonical Wnt signaling pathway IEA
 cellular_componentGO:0005623 cell IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0035198 miRNA binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IDA
 molecular_functionGO:0044212 transcription regulatory region DNA binding IEA


Pathways (from Reactome)
Pathway description
Deactivation of the beta-catenin transactivating complex


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr