ENSGALG00000036497


Gallus gallus

Features
Gene ID: ENSGALG00000036497
  
Biological name :SOX4
  
Synonyms : SOX4 / transcription factor SOX-4
  
Possible biological names infered from orthology : Q06831 / Q06945 / SRY-box 4
  
Species: Gallus gallus
  
Chr. number: 2
Strand: -1
Band:
Gene start: 59096907
Gene end: 59098672
  
Corresponding Affymetrix probe sets: Gga.7732.1.S1_at (Chicken Array)   Gga.9314.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000050194
NCBI entrez gene - 395143     See in Manteia.
RefSeq - NM_204484
RefSeq Peptide - NP_989815
swissprot - A0A1D5PBR4
Ensembl - ENSGALG00000036497
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sox4aENSDARG00000004588Danio rerio
 sox4bENSDARG00000098834Danio rerio
 SOX4ENSG00000124766Homo sapiens
 Sox4ENSMUSG00000076431Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SOX12 / SRY-box 12 / O15370* / Q04890* / Transcription factor SOX-12 *ENSGALG0000003595132
SOX10 / Q9W757 / Transcription factor SOX-10 / Q04888* / P56693* / SRY-box 10*ENSGALG0000001229021
SOX9 / P48434 / Transcription factor SOX-9 / Q04887* / P48436* / SRY-box 9*ENSGALG0000000438619
SOX7* / Q9BT81* / P40646* / SRY-box 7* / AC105001.2* / SRY (sex determining region Y)-box 7*ENSGALG0000004129619
SOX8 / transcription factor SOX-8 / Q04886* / P57073* / SRY-box 8* / SRY (sex determining region Y)-box 8*ENSGALG0000000526319
SOX2 / P48430 / Transcription factor SOX-2 / P48431* / SRY-box 2*ENSGALG0000004346018
SOX17 / transcription factor SOX-17 / Q61473* / Q9H6I2* / SRY-box 17*ENSGALG0000003285118
SOX17* / Q61473* / Q9H6I2* / SRY-box 17* / Transcription factor SOX-17 *ENSGALG0000003299418
SOX1 / transcription factor SOX-1 / O00570* / P53783* / SRY-box 1*ENSGALG0000003035318
SOX18 / transcription factor SOX-18 / P35713* / P43680* / SRY-box 18*ENSGALG0000003411817
SOX14 / Q9W7R6 / Transcription factor SOX-14 / Q04892* / O95416* / SRY-box 14*ENSGALG0000003735215
SOX21 / Q9W7R5 / Transcription factor SOX-21 / Q9Y651* / Q811W0* / SRY-box 21*ENSGALG0000003515715


Protein motifs (from Interpro)
Interpro ID Name
 IPR009071  High mobility group box domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001501 skeletal system development IEA
 biological_processGO:0001841 neural tube formation IEA
 biological_processGO:0002328 pro-B cell differentiation IEA
 biological_processGO:0003183 mitral valve morphogenesis IEA
 biological_processGO:0003211 cardiac ventricle formation IEA
 biological_processGO:0003215 cardiac right ventricle morphogenesis IEA
 biological_processGO:0003289 atrial septum primum morphogenesis IEA
 biological_processGO:0003357 noradrenergic neuron differentiation IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest IEA
 biological_processGO:0007507 heart development IEA
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0014009 glial cell proliferation IEA
 biological_processGO:0021510 spinal cord development IEA
 biological_processGO:0021522 spinal cord motor neuron differentiation IEA
 biological_processGO:0021782 glial cell development IEA
 biological_processGO:0030177 positive regulation of Wnt signaling pathway IEA
 biological_processGO:0030217 T cell differentiation IEA
 biological_processGO:0031018 endocrine pancreas development IEA
 biological_processGO:0031397 negative regulation of protein ubiquitination IEA
 biological_processGO:0031647 regulation of protein stability IEA
 biological_processGO:0032024 positive regulation of insulin secretion IEA
 biological_processGO:0035019 somatic stem cell population maintenance IEA
 biological_processGO:0035910 ascending aorta morphogenesis IEA
 biological_processGO:0042593 glucose homeostasis IEA
 biological_processGO:0042769 DNA damage response, detection of DNA damage IEA
 biological_processGO:0043065 positive regulation of apoptotic process IEA
 biological_processGO:0045727 positive regulation of translation IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0046826 negative regulation of protein export from nucleus IEA
 biological_processGO:0048485 sympathetic nervous system development IEA
 biological_processGO:0050821 protein stabilization IEA
 biological_processGO:0060070 canonical Wnt signaling pathway IEA
 biological_processGO:0060174 limb bud formation IEA
 biological_processGO:0060412 ventricular septum morphogenesis IEA
 biological_processGO:0060548 negative regulation of cell death IEA
 biological_processGO:0060563 neuroepithelial cell differentiation IEA
 biological_processGO:0060993 kidney morphogenesis IEA
 biological_processGO:0071333 cellular response to glucose stimulus IEA
 biological_processGO:0090263 positive regulation of canonical Wnt signaling pathway IEA
 biological_processGO:2000761 positive regulation of N-terminal peptidyl-lysine acetylation IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0044798 nuclear transcription factor complex IEA
 molecular_functionGO:0000976 transcription regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IEA
 molecular_functionGO:0001046 core promoter sequence-specific DNA binding IEA
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0046982 protein heterodimerization activity IEA


Pathways (from Reactome)
Pathway description
Deactivation of the beta-catenin transactivating complex


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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