ENSGALG00000005263


Gallus gallus

Features
Gene ID: ENSGALG00000005263
  
Biological name :SOX8
  
Synonyms : SOX8 / transcription factor SOX-8
  
Possible biological names infered from orthology : P57073 / Q04886 / SRY-box 8 / SRY (sex determining region Y)-box 8
  
Species: Gallus gallus
  
Chr. number: 14
Strand: -1
Band:
Gene start: 5774171
Gene end: 5777561
  
Corresponding Affymetrix probe sets: Gga.4309.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000008435
NCBI entrez gene - 395483     See in Manteia.
RefSeq - NM_204731
RefSeq Peptide - NP_990062
swissprot - F1P1Z5
Ensembl - ENSGALG00000005263
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sox8aENSDARG00000105301Danio rerio
 sox8bENSDARG00000037782Danio rerio
 sox9bENSDARG00000043923Danio rerio
 SOX8ENSG00000005513Homo sapiens
 Sox8ENSMUSG00000024176Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SOX9 / P48434 / Transcription factor SOX-9 / Q04887* / P48436* / SRY-box 9*ENSGALG0000000438655
SOX10 / Q9W757 / Transcription factor SOX-10 / Q04888* / P56693* / SRY-box 10*ENSGALG0000001229048
SOX17* / Q61473* / Q9H6I2* / SRY-box 17* / Transcription factor SOX-17 *ENSGALG0000003299423
SOX17 / transcription factor SOX-17 / Q61473* / Q9H6I2* / SRY-box 17*ENSGALG0000003285122
SOX7* / Q9BT81* / P40646* / SRY-box 7* / AC105001.2* / SRY (sex determining region Y)-box 7*ENSGALG0000004129620
SOX18 / transcription factor SOX-18 / P35713* / P43680* / SRY-box 18*ENSGALG0000003411820
SOX2 / P48430 / Transcription factor SOX-2 / P48431* / SRY-box 2*ENSGALG0000004346017
SOX4 / transcription factor SOX-4 / Q06831* / Q06945* / SRY-box 4*ENSGALG0000003649717
SOX1 / transcription factor SOX-1 / O00570* / P53783* / SRY-box 1*ENSGALG0000003035316
SOX21 / Q9W7R5 / Transcription factor SOX-21 / Q9Y651* / Q811W0* / SRY-box 21*ENSGALG0000003515715
SOX14 / Q9W7R6 / Transcription factor SOX-14 / Q04892* / O95416* / SRY-box 14*ENSGALG0000003735215
SOX12 / SRY-box 12 / O15370* / Q04890* / Transcription factor SOX-12 *ENSGALG0000003595114


Protein motifs (from Interpro)
Interpro ID Name
 IPR009071  High mobility group box domain
 IPR022151  Sox developmental protein N-terminal
 IPR031265  Transcription factor SOX-8


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001649 osteoblast differentiation IEA
 biological_processGO:0001701 in utero embryonic development IEA
 biological_processGO:0001755 neural crest cell migration IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007283 spermatogenesis IEA
 biological_processGO:0007422 peripheral nervous system development IEA
 biological_processGO:0008584 male gonad development IEA
 biological_processGO:0010628 positive regulation of gene expression IEA
 biological_processGO:0010817 regulation of hormone levels IEA
 biological_processGO:0014015 positive regulation of gliogenesis IEA
 biological_processGO:0033690 positive regulation of osteoblast proliferation IEA
 biological_processGO:0035914 skeletal muscle cell differentiation IEA
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 biological_processGO:0045165 cell fate commitment IEA
 biological_processGO:0045444 fat cell differentiation IEA
 biological_processGO:0045662 negative regulation of myoblast differentiation IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0046533 negative regulation of photoreceptor cell differentiation IEA
 biological_processGO:0048469 cell maturation IEA
 biological_processGO:0048484 enteric nervous system development IEA
 biological_processGO:0048709 oligodendrocyte differentiation IEA
 biological_processGO:0060009 Sertoli cell development IEA
 biological_processGO:0060018 astrocyte fate commitment IEA
 biological_processGO:0060041 retina development in camera-type eye IEA
 biological_processGO:0060221 retinal rod cell differentiation IEA
 biological_processGO:0060612 adipose tissue development IEA
 biological_processGO:0061138 morphogenesis of a branching epithelium IEA
 biological_processGO:0072034 renal vesicle induction IEA
 biological_processGO:0072197 ureter morphogenesis IEA
 biological_processGO:0072289 metanephric nephron tubule formation IEA
 biological_processGO:0090184 positive regulation of kidney development IEA
 biological_processGO:0090190 positive regulation of branching involved in ureteric bud morphogenesis IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0044798 nuclear transcription factor complex IEA
 molecular_functionGO:0000979 RNA polymerase II core promoter sequence-specific DNA binding IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0008134 transcription factor binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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