ENSDARG00000043923


Danio rerio

Features
Gene ID: ENSDARG00000043923
  
Biological name :sox9b
  
Synonyms : sox9b / SRY (sex determining region Y)-box 9b
  
Possible biological names infered from orthology : P57073 / Q04886 / SOX8 / SRY-box 8 / SRY (sex determining region Y)-box 8
  
Species: Danio rerio
  
Chr. number: 3
Strand: -1
Band:
Gene start: 62521041
Gene end: 62527696
  
Corresponding Affymetrix probe sets: Dr.11850.1.S1_at (Zebrafish Array)   Dr.11850.1.S2_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000064499
Ensembl peptide - ENSDARP00000127691
NCBI entrez gene - 60642     See in Manteia.
swissprot - Q9DFH1
swissprot - X1WBU9
ZFIN ID - ZDB-GENE-001103-2
Ensembl - ENSDARG00000043923
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SOX8ENSGALG00000005263Gallus gallus
 SOX8ENSG00000005513Homo sapiens
 Sox8ENSMUSG00000024176Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
sox9a / SRY (sex determining region Y)-box 9a / SOX9* / Q04887* / P48436* / SRY-box 9* / Transcription factor SOX-9 *ENSDARG0000000329370
sox10 / SRY (sex determining region Y)-box 10 / Q04888* / P56693* / SRY-box 10* / Transcription factor SOX-10 *ENSDARG0000007746752
sox8b / SRY (sex determining region Y)-box 8b / SOX8* / P57073* / SRY-box 8*ENSDARG0000003778249
sox8a / SRY (sex determining region Y)-box 8a / SOX8* / P57073* / SRY-box 8*ENSDARG0000010530146
sox7 / SRY (sex determining region Y)-box 7 / Q9BT81* / P40646* / SRY-box 7* / AC105001.2*ENSDARG0000003012523
sox17 / SRY (sex determining region Y)-box 17 / Q9H6I2* / SRY-box 17*ENSDARG0000010171722
sox18 / SRY (sex determining region Y)-box 18 / P43680* / P35713* / SRY-box 18* / Transcription factor SOX-18 *ENSDARG0000005859822
sox1b / Q2Z1R2 / SRY (sex determining region Y)-box 1b / SOX1* / P53783* / O00570* / SRY-box 1* / Transcription factor SOX-1 *ENSDARG0000000813119
sox2 / Q6P0E1 / SRY (sex determining region Y)-box 2 / P48431* / SRY-box 2*ENSDARG0000007091318
sox4b / SRY (sex determining region Y)-box 4b / SOX4* / Q06945* / SRY-box 4*ENSDARG0000009883418
sox1a / Q6DGL6 / SRY (sex determining region Y)-box 1a / SOX1* / P53783* / O00570* / SRY-box 1* / Transcription factor SOX-1 *ENSDARG0000006986618
sox3 / Q6EJB7 / SRY (sex determining region Y)-box 3 / P41225* / SRY-box 3*ENSDARG0000005356918
sox4a / SRY (sex determining region Y)-box 4a / SOX4* / Q06945* / Q06831* / SRY-box 4* / Transcription factor SOX-4 *ENSDARG0000000458818
sox12 / SRY (sex determining region Y)-box 12 / Q04890* / O15370* / SRY-box 12* / Transcription factor SOX-12 *ENSDARG0000002584717
sox19b / SRY (sex determining region Y)-box 19bENSDARG0000004026617
sox11b / SRY (sex determining region Y)-box 11b / SOX11* / Q7M6Y2* / P35716* / SRY-box 11* / Transcription factor SOX-11 *ENSDARG0000009574317
sox11a / SRY (sex determining region Y)-box 11a / SOX11* / Q7M6Y2* / P35716* / SRY-box 11* / Transcription factor SOX-11 *ENSDARG0000007781116
sox14 / Q32PP9 / SRY (sex determining region Y)-box 14 / Q04892* / O95416* / SRY-box 14* / Transcription factor SOX-14 *ENSDARG0000007092916
P47792 / sox19a / SRY (sex determining region Y)-box 19aENSDARG0000001077016
Q6RVD7 / sox21b / SRY (sex determining region Y)-box 21b / SOX21* / Q9Y651* / Q811W0* / SRY-box 21* / Transcription factor SOX-21 *ENSDARG0000000854015


Protein motifs (from Interpro)
Interpro ID Name
 IPR009071  High mobility group box domain
 IPR022151  Sox developmental protein N-terminal
 IPR029548  Transcription factor SOX-9


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003170 heart valve development IMP
 biological_processGO:0003309 type B pancreatic cell differentiation IMP
 biological_processGO:0003342 proepicardium development IMP
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0030318 melanocyte differentiation IMP
 biological_processGO:0030916 otic vesicle formation IGI
 biological_processGO:0031016 pancreas development IMP
 biological_processGO:0031018 endocrine pancreas development IMP
 biological_processGO:0031099 regeneration IMP
 biological_processGO:0035118 embryonic pectoral fin morphogenesis IMP
 biological_processGO:0043049 otic placode formation IMP
 biological_processGO:0048839 inner ear development IMP
 biological_processGO:0050935 iridophore differentiation IMP
 biological_processGO:0051216 cartilage development IMP
 biological_processGO:0060021 roof of mouth development IMP
 biological_processGO:0060041 retina development in camera-type eye IMP
 biological_processGO:0061008 hepaticobiliary system development IMP
 biological_processGO:0061032 visceral serous pericardium development IMP
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000037 anatomical structure anatomical structure decreased amount , abnormal
Show

 ZFA:0000051 otic vesicle otic vesicle aplastic , abnormal
otic vesicle decreased size , abnormal
Show

 ZFA:0000054 pericardium pericardium edematous , abnormal
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 ZFA:0000089 fin fold actinotrichium fin fold actinotrichium decreased amount , abnormal
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 ZFA:0000114 heart heart malformed , abnormal
heart lacks all parts of type ventricular epicardium cell, abnormal
heart elongated , abnormal
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 ZFA:0000123 liver liver green , abnormal
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 ZFA:0000140 pancreas pancreas green , abnormal
pancreas acinar cell decreased amount , abnormal
Show

 ZFA:0000184 cleithrum cleithrum decreased size , abnormal
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 ZFA:0000191 dentary dentary aplastic , abnormal
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 ZFA:0000200 dorsal root ganglion dorsal root ganglion irregular spatial pattern , abnormal
dorsal root ganglion decreased amount , abnormal
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 ZFA:0000208 gall bladder gall bladder decreased size , abnormal
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 ZFA:0000250 opercle opercle decreased size , abnormal
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 ZFA:0000270 maxilla maxilla aplastic , abnormal
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 ZFA:0000422 retroarticular retroarticular aplastic , abnormal
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 ZFA:0000476 branchiostegal ray branchiostegal ray aplastic , abnormal
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 ZFA:0000561 parasphenoid parasphenoid decreased size , abnormal
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 ZFA:0000578 ceratohyal bone ceratohyal bone aplastic , abnormal
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 ZFA:0000657 entopterygoid entopterygoid aplastic , abnormal
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 ZFA:0000672 hyomandibula hyomandibula aplastic , abnormal
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 ZFA:0001094 whole organism whole organism decreased life span , abnormal
whole organism decreased size , abnormal
whole organism decreased thickness , abnormal
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 ZFA:0001114 head head decreased size , abnormal
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 ZFA:0001117 post-vent region post-vent region increased curvature , abnormal
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 ZFA:0001205 Meckel s cartilage Meckels cartilage decreased size , abnormal
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 ZFA:0001239 ceratobranchial 5 bone ceratobranchial 5 bone aplastic , abnormal
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 ZFA:0001260 endocrine pancreas endocrine pancreas mislocalised , abnormal
endocrine pancreas lacks all parts of type secondary islet , abnormal
endocrine pancreas has fewer parts of type insulin secreting cell , abnormal
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 ZFA:0001321 neurocranial trabecula neurocranial trabecula decreased size , abnormal
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 ZFA:0001372 pancreatic duct pancreatic duct has fewer parts of type cell , abnormal
pancreatic duct malformed , abnormal
pancreatic duct morphology , abnormal
pancreatic duct dilated , abnormal
pancreatic duct decreased branchiness , abnormal
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 ZFA:0001399 palatoquadrate cartilage palatoquadrate cartilage decreased size , abnormal
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 ZFA:0001400 ceratohyal cartilage ceratohyal cartilage decreased size , abnormal
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 ZFA:0001405 ethmoid cartilage ethmoid cartilage decreased size , abnormal
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 ZFA:0001422 hyosymplectic cartilage hyosymplectic cartilage decreased size , abnormal
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 ZFA:0001425 basal plate cartilage basal plate cartilage decreased size , abnormal
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 ZFA:0001456 pectoral fin endoskeletal disc pectoral fin endoskeletal disc decreased size , abnormal
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 ZFA:0001504 occipital arch cartilage occipital arch cartilage decreased size , abnormal
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 ZFA:0001516 ceratobranchial cartilage ceratobranchial cartilage decreased size , abnormal
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 ZFA:0005162 digestive system duct digestive system duct amorphous , abnormal
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 ZFA:0005163 bile canaliculus bile canaliculus decreased length , abnormal
bile canaliculus increased width , abnormal
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 ZFA:0005169 intrahepatic bile duct intrahepatic bile duct malformed , abnormal
intrahepatic bile duct morphology , abnormal
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 ZFA:0005754 primary islet primary islet decreased size , abnormal
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 ZFA:0005756 secondary islet secondary islet increased amount , abnormal
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 ZFA:0005808 proepicardial cluster proepicardial cluster absent , abnormal
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 ZFA:0009091 melanocyte melanocyte increased size , abnormal
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 ZFA:0009102 pancreatic B cell pancreatic B cell regeneration increased rate , abnormal
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 ZFA:0009111 hepatocyte hepatocyte organization quality , abnormal
hepatocyte regeneration decreased occurrence , abnormal
hepatocyte regeneration decreased process quality , abnormal
hepatocyte regenerating tissue decreased amount , abnormal
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 ZFA:0009199 iridophore iridophore decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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