ENSDARG00000101717


Danio rerio

Features
Gene ID: ENSDARG00000101717
  
Biological name :sox17
  
Synonyms : sox17 / SRY (sex determining region Y)-box 17
  
Possible biological names infered from orthology : Q61473 / Q9H6I2 / SRY-box 17 / Transcription factor SOX-17
  
Species: Danio rerio
  
Chr. number: 7
Strand: -1
Band:
Gene start: 58772209
Gene end: 58776400
  
Corresponding Affymetrix probe sets: Dr.8107.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000135455
NCBI entrez gene - 30544     See in Manteia.
swissprot - Q5PQZ5
ZFIN ID - ZDB-GENE-991213-1
Ensembl - ENSDARG00000101717
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000032994Gallus gallus
 SOX17ENSGALG00000032851Gallus gallus
 SOX17ENSG00000164736Homo sapiens
 Sox17ENSMUSG00000025902Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
sox18 / SRY (sex determining region Y)-box 18 / P43680* / P35713* / SRY-box 18* / Transcription factor SOX-18 *ENSDARG0000005859834
sox7 / SRY (sex determining region Y)-box 7 / Q9BT81* / P40646* / SRY-box 7* / AC105001.2*ENSDARG0000003012532
sox9a / SRY (sex determining region Y)-box 9a / SOX9* / Q04887* / P48436* / SRY-box 9* / Transcription factor SOX-9 *ENSDARG0000000329323
sox9b / SRY (sex determining region Y)-box 9b / SOX8* / P57073* / SRY-box 8*ENSDARG0000004392321
sox8b / SRY (sex determining region Y)-box 8b / SOX8* / P57073* / SRY-box 8*ENSDARG0000003778220
sox10 / SRY (sex determining region Y)-box 10 / Q04888* / P56693* / SRY-box 10* / Transcription factor SOX-10 *ENSDARG0000007746720
sox8a / SRY (sex determining region Y)-box 8a / SOX8* / P57073* / SRY-box 8*ENSDARG0000010530120
sox32 / SRY (sex determining region Y)-box 32 / SOX17* / Q9H6I2* / SRY-box 17*ENSDARG0000010059119
sox11a / SRY (sex determining region Y)-box 11a / SOX11* / Q7M6Y2* / P35716* / SRY-box 11* / Transcription factor SOX-11 *ENSDARG0000007781118
sox4b / SRY (sex determining region Y)-box 4b / SOX4* / Q06945* / SRY-box 4*ENSDARG0000009883417
sox11b / SRY (sex determining region Y)-box 11b / SOX11* / Q7M6Y2* / P35716* / SRY-box 11* / Transcription factor SOX-11 *ENSDARG0000009574317
sox4a / SRY (sex determining region Y)-box 4a / SOX4* / Q06945* / Q06831* / SRY-box 4* / Transcription factor SOX-4 *ENSDARG0000000458817
sox1a / Q6DGL6 / SRY (sex determining region Y)-box 1a / SOX1* / P53783* / O00570* / SRY-box 1* / Transcription factor SOX-1 *ENSDARG0000006986617
sox12 / SRY (sex determining region Y)-box 12 / Q04890* / O15370* / SRY-box 12* / Transcription factor SOX-12 *ENSDARG0000002584716
sox2 / Q6P0E1 / SRY (sex determining region Y)-box 2 / P48431* / SRY-box 2*ENSDARG0000007091316
sox3 / Q6EJB7 / SRY (sex determining region Y)-box 3 / P41225* / SRY-box 3*ENSDARG0000005356916
sox1b / Q2Z1R2 / SRY (sex determining region Y)-box 1b / SOX1* / P53783* / O00570* / SRY-box 1* / Transcription factor SOX-1 *ENSDARG0000000813115
sox19b / SRY (sex determining region Y)-box 19bENSDARG0000004026614
P47792 / sox19a / SRY (sex determining region Y)-box 19aENSDARG0000001077014
sox14 / Q32PP9 / SRY (sex determining region Y)-box 14 / Q04892* / O95416* / SRY-box 14* / Transcription factor SOX-14 *ENSDARG0000007092914


Protein motifs (from Interpro)
Interpro ID Name
 IPR009071  High mobility group box domain
 IPR033392  Sox 7/17/18, central domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0035469 determination of pancreatic left/right asymmetry IMP
 biological_processGO:0060215 primitive hemopoiesis IMP
 biological_processGO:0061371 determination of heart left/right asymmetry IMP
 biological_processGO:0070121 Kupffer"s vesicle development IMP
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA


Pathways (from Reactome)
Pathway description
Deactivation of the beta-catenin transactivating complex


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000001 Kupffer s vesicle Kupffers vesicle decreased size , abnormal
Kupffers vesicle bilateral , abnormal
Kupffers vesicle inverted , abnormal
Show

 ZFA:0000008 brain brain symmetry , abnormal
Show

 ZFA:0000033 intermediate cell mass of mesoderm intermediate cell mass of mesoderm decreased amount , abnormal
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 ZFA:0000041 mesoderm mesoderm anterior side decreased amount , abnormal
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 ZFA:0000054 pericardium pericardium edematous , abnormal
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 ZFA:0000092 axis axis decreased length , abnormal
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 ZFA:0000106 extension extension increased thickness , abnormal
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 ZFA:0000112 gut gut duplicated , abnormal
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 ZFA:0000123 liver liver duplicated , abnormal
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 ZFA:0000140 pancreas pancreas morphology , abnormal
pancreas duplicated , abnormal
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 ZFA:0000149 primitive heart tube primitive heart tube bilateral , abnormal
primitive heart tube inverted , abnormal
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 ZFA:0000155 somite somite decreased amount , abnormal
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 ZFA:0001094 whole organism whole organism increased amount , abnormal
whole organism decreased amount , abnormal
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 ZFA:0001260 endocrine pancreas endocrine pancreas inverted , abnormal
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 ZFA:0009325 erythroid lineage cell erythroid lineage cell decreased amount , abnormal
erythroid lineage cell cell cycle G1/S phase transition delayed , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000014571 ctnnb1 / catenin (cadherin-associated protein), beta 1 / P35222* / catenin beta 1*  / complex / reaction
 ENSDARG00000031894 lef1 / lymphoid enhancer-binding factor 1 / P27782* / Q9UJU2*  / reaction / complex






 

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