ENSDARG00000095743


Danio rerio

Features
Gene ID: ENSDARG00000095743
  
Biological name :sox11b
  
Synonyms : sox11b / SRY (sex determining region Y)-box 11b
  
Possible biological names infered from orthology : P35716 / Q7M6Y2 / SOX11 / SRY-box 11 / Transcription factor SOX-11
  
Species: Danio rerio
  
Chr. number: 20
Strand: -1
Band:
Gene start: 30032628
Gene end: 30035326
  
Corresponding Affymetrix probe sets: Dr.5112.1.S1_at (Zebrafish Array)   Dr.5112.1.S2_at (Zebrafish Array)   Dr.5112.1.S3_at (Zebrafish Array)   NM_131337_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000122216
NCBI entrez gene - 30603     See in Manteia.
RefSeq - NM_131337
RefSeq Peptide - NP_571412
swissprot - Q5TZG4
ZFIN ID - ZDB-GENE-980526-466
Ensembl - ENSDARG00000095743
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SOX11ENSG00000176887Homo sapiens
 Sox11ENSMUSG00000063632Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
sox11a / SRY (sex determining region Y)-box 11a / SOX11* / Q7M6Y2* / P35716* / SRY-box 11* / Transcription factor SOX-11 *ENSDARG0000007781168
sox4a / SRY (sex determining region Y)-box 4a / SOX4* / Q06945* / Q06831* / SRY-box 4* / Transcription factor SOX-4 *ENSDARG0000000458842
sox12 / SRY (sex determining region Y)-box 12 / Q04890* / O15370* / SRY-box 12* / Transcription factor SOX-12 *ENSDARG0000002584740
sox4b / SRY (sex determining region Y)-box 4b / SOX4* / Q06945* / SRY-box 4*ENSDARG0000009883439
sox9a / SRY (sex determining region Y)-box 9a / SOX9* / Q04887* / P48436* / SRY-box 9* / Transcription factor SOX-9 *ENSDARG0000000329321
sox7 / SRY (sex determining region Y)-box 7 / Q9BT81* / P40646* / SRY-box 7* / AC105001.2*ENSDARG0000003012520
sox8a / SRY (sex determining region Y)-box 8a / SOX8* / P57073* / SRY-box 8*ENSDARG0000010530120
sox2 / Q6P0E1 / SRY (sex determining region Y)-box 2 / P48431* / SRY-box 2*ENSDARG0000007091320
sox3 / Q6EJB7 / SRY (sex determining region Y)-box 3 / P41225* / SRY-box 3*ENSDARG0000005356920
sox10 / SRY (sex determining region Y)-box 10 / Q04888* / P56693* / SRY-box 10* / Transcription factor SOX-10 *ENSDARG0000007746720
sox8b / SRY (sex determining region Y)-box 8b / SOX8* / P57073* / SRY-box 8*ENSDARG0000003778219
sox17 / SRY (sex determining region Y)-box 17 / Q9H6I2* / SRY-box 17*ENSDARG0000010171719
sox21a / SRY (sex determining region Y)-box 21aENSDARG0000003166419
sox1a / Q6DGL6 / SRY (sex determining region Y)-box 1a / SOX1* / P53783* / O00570* / SRY-box 1* / Transcription factor SOX-1 *ENSDARG0000006986619
sox1b / Q2Z1R2 / SRY (sex determining region Y)-box 1b / SOX1* / P53783* / O00570* / SRY-box 1* / Transcription factor SOX-1 *ENSDARG0000000813119
sox19b / SRY (sex determining region Y)-box 19bENSDARG0000004026618
sox14 / Q32PP9 / SRY (sex determining region Y)-box 14 / Q04892* / O95416* / SRY-box 14* / Transcription factor SOX-14 *ENSDARG0000007092918
Q6RVD7 / sox21b / SRY (sex determining region Y)-box 21b / SOX21* / Q9Y651* / Q811W0* / SRY-box 21* / Transcription factor SOX-21 *ENSDARG0000000854018
sox9b / SRY (sex determining region Y)-box 9b / SOX8* / P57073* / SRY-box 8*ENSDARG0000004392318
sox18 / SRY (sex determining region Y)-box 18 / P43680* / P35713* / SRY-box 18* / Transcription factor SOX-18 *ENSDARG0000005859818


Protein motifs (from Interpro)
Interpro ID Name
 IPR009071  High mobility group box domain
 IPR017386  Transcription factor SOX-11/4
 IPR029551  Transcription factor SOX-11


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002088 lens development in camera-type eye IGI
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007420 brain development IMP
 biological_processGO:0009611 response to wounding IMP
 biological_processGO:0009953 dorsal/ventral pattern formation IDA
 biological_processGO:0030182 neuron differentiation IMP
 biological_processGO:0045879 negative regulation of smoothened signaling pathway IGI
 biological_processGO:0046548 retinal rod cell development IGI
 biological_processGO:0048593 camera-type eye morphogenesis IGI
 biological_processGO:0061386 closure of optic fissure IGI
 biological_processGO:1903670 regulation of sprouting angiogenesis IMP
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain cell apoptotic , abnormal
Show

 ZFA:0000012 central nervous system central nervous system apoptotic , abnormal
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 ZFA:0000029 hindbrain hindbrain axon decreased amount , abnormal
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 ZFA:0000035 lens lens malformed , abnormal
lens apoptotic process increased process quality , abnormal
Show

 ZFA:0000050 optic vesicle optic vesicle apoptotic process increased process quality , abnormal
optic vesicle cell proliferation increased process quality , abnormal
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 ZFA:0000075 spinal cord spinal cord ependymal cell proliferative , abnormal
Show

 ZFA:0000079 telencephalon telencephalon neuron decreased amount , abnormal
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 ZFA:0000101 diencephalon diencephalon neuron decreased amount , abnormal
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 ZFA:0000107 eye eye decreased size , abnormal
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 ZFA:0000144 retinal pigmented epithelium retinal pigmented epithelium open , abnormal
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 ZFA:0000152 retina retina cell proliferation increased process quality , abnormal
retina protruding out of brain , abnormal
retina has fewer parts of type retinal rod cell , abnormal
retina ventral region immature , abnormal
retina ventral region decreased pigmentation , abnormal
Show

 ZFA:0001058 caudal fin caudal fin kinked , abnormal
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 ZFA:0001094 whole organism whole organism lethal (sensu genetics) , abnormal
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 ZFA:0001114 head head decreased size , abnormal
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 ZFA:0001284 optic fissure optic fissure closure incomplete , abnormal
optic fissure open , abnormal
Show

 ZFA:0001285 intersegmental vessel intersegmental vessel decreased length , abnormal
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 ZFA:0001286 caudal vein plexus caudal vein plexus angiogenic sprout decreased amount , abnormal
caudal vein plexus morphology , abnormal
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 ZFA:0001692 hindbrain commissure hindbrain commissure disorganized , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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