ENSDARG00000004588


Danio rerio

Features
Gene ID: ENSDARG00000004588
  
Biological name :sox4a
  
Synonyms : sox4a / SRY (sex determining region Y)-box 4a
  
Possible biological names infered from orthology : Q06831 / Q06945 / SOX4 / SRY-box 4 / Transcription factor SOX-4
  
Species: Danio rerio
  
Chr. number: 19
Strand: -1
Band:
Gene start: 28786149
Gene end: 28789409
  
Corresponding Affymetrix probe sets: Dr.20124.1.A1_at (Zebrafish Array)   NM_213122_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000002932
Ensembl peptide - ENSDARP00000156470
NCBI entrez gene - 336346     See in Manteia.
RefSeq - NM_213122
RefSeq Peptide - NP_998287
swissprot - Q6A3P6
swissprot - Q6P0Z4
ZFIN ID - ZDB-GENE-030131-8290
Ensembl - ENSDARG00000004588
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SOX4ENSGALG00000036497Gallus gallus
 SOX4ENSG00000124766Homo sapiens
 Sox4ENSMUSG00000076431Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
sox4b / SRY (sex determining region Y)-box 4b / SOX4* / Q06945* / SRY-box 4*ENSDARG0000009883463
sox11a / SRY (sex determining region Y)-box 11a / SOX11* / Q7M6Y2* / P35716* / SRY-box 11* / Transcription factor SOX-11 *ENSDARG0000007781142
sox11b / SRY (sex determining region Y)-box 11b / SOX11* / Q7M6Y2* / P35716* / SRY-box 11* / Transcription factor SOX-11 *ENSDARG0000009574342
sox12 / SRY (sex determining region Y)-box 12 / Q04890* / O15370* / SRY-box 12* / Transcription factor SOX-12 *ENSDARG0000002584739
sox9a / SRY (sex determining region Y)-box 9a / SOX9* / Q04887* / P48436* / SRY-box 9* / Transcription factor SOX-9 *ENSDARG0000000329322
sox8a / SRY (sex determining region Y)-box 8a / SOX8* / P57073* / SRY-box 8*ENSDARG0000010530121
sox10 / SRY (sex determining region Y)-box 10 / Q04888* / P56693* / SRY-box 10* / Transcription factor SOX-10 *ENSDARG0000007746721
sox17 / SRY (sex determining region Y)-box 17 / Q9H6I2* / SRY-box 17*ENSDARG0000010171720
sox18 / SRY (sex determining region Y)-box 18 / P43680* / P35713* / SRY-box 18* / Transcription factor SOX-18 *ENSDARG0000005859820
sox9b / SRY (sex determining region Y)-box 9b / SOX8* / P57073* / SRY-box 8*ENSDARG0000004392320
sox8b / SRY (sex determining region Y)-box 8b / SOX8* / P57073* / SRY-box 8*ENSDARG0000003778220
sox3 / Q6EJB7 / SRY (sex determining region Y)-box 3 / P41225* / SRY-box 3*ENSDARG0000005356919
sox21a / SRY (sex determining region Y)-box 21aENSDARG0000003166419
sox7 / SRY (sex determining region Y)-box 7 / Q9BT81* / P40646* / SRY-box 7* / AC105001.2*ENSDARG0000003012519
Q6RVD7 / sox21b / SRY (sex determining region Y)-box 21b / SOX21* / Q9Y651* / Q811W0* / SRY-box 21* / Transcription factor SOX-21 *ENSDARG0000000854018
sox1a / Q6DGL6 / SRY (sex determining region Y)-box 1a / SOX1* / P53783* / O00570* / SRY-box 1* / Transcription factor SOX-1 *ENSDARG0000006986618
sox14 / Q32PP9 / SRY (sex determining region Y)-box 14 / Q04892* / O95416* / SRY-box 14* / Transcription factor SOX-14 *ENSDARG0000007092918
sox2 / Q6P0E1 / SRY (sex determining region Y)-box 2 / P48431* / SRY-box 2*ENSDARG0000007091318
sox1b / Q2Z1R2 / SRY (sex determining region Y)-box 1b / SOX1* / P53783* / O00570* / SRY-box 1* / Transcription factor SOX-1 *ENSDARG0000000813118
sox19b / SRY (sex determining region Y)-box 19bENSDARG0000004026617


Protein motifs (from Interpro)
Interpro ID Name
 IPR009071  High mobility group box domain
 IPR017386  Transcription factor SOX-11/4


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0045879 negative regulation of smoothened signaling pathway IGI
 biological_processGO:0061386 closure of optic fissure IGI
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA


Pathways (from Reactome)
Pathway description
Deactivation of the beta-catenin transactivating complex


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000014571 ctnnb1 / catenin (cadherin-associated protein), beta 1 / P35222* / catenin beta 1*  / complex / reaction
 ENSDARG00000031894 lef1 / lymphoid enhancer-binding factor 1 / P27782* / Q9UJU2*  / reaction / complex






 

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