ENSMUSG00000000711


Mus musculus

Features
Gene ID: ENSMUSG00000000711
  
Biological name :Rab5b
  
Synonyms : P61021 / Rab5b / RAB5B, member RAS oncogene family
  
Possible biological names infered from orthology : P61020
  
Species: Mus musculus
  
Chr. number: 10
Strand: -1
Band: D3
Gene start: 128677175
Gene end: 128696264
  
Corresponding Affymetrix probe sets: 10373521 (MoGene1.0st)   10486057 (MoGene1.0st)   1422119_at (Mouse Genome 430 2.0 Array)   1437446_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000000727
NCBI entrez gene - 19344     See in Manteia.
MGI - MGI:105938
RefSeq - XM_006513384
RefSeq - NM_177411
RefSeq Peptide - NP_803130
swissprot - P61021
swissprot - B2RPS1
Ensembl - ENSMUSG00000000711
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RAB5BENSGALG00000042482Gallus gallus
 RAB5BENSG00000111540Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Rab5c / P35278 / RAB5C, member RAS oncogene family / P51148*ENSMUSG0000001917385
Rab5a / Q9CQD1 / Ras-related protein Rab-5A / P20339* / RAB5A, member RAS oncogene family*ENSMUSG0000001783182
Rab31 / RAB31, member RAS oncogene family / Q13636*ENSMUSG0000005651545
P35285 / Rab22a / RAB22A, member RAS oncogene family / Q9UL26*ENSMUSG0000002751944
Rab17 / P35292 / Ras-related protein Rab-17 / Q9H0T7* / RAB17, member RAS oncogene family*ENSMUSG0000002630438
Rab21 / P35282 / RAB21, member RAS oncogene family / Q9UL25*ENSMUSG0000002013238
Rab20 / P35295 / Ras-related protein Rab-20 / Q9NX57* / RAB20, member RAS oncogene family*ENSMUSG0000003150430
Q8CFP6 / Dnajc27 / DnaJ homolog subfamily C member 27 / Q9NZQ0* / DnaJ heat shock protein family (Hsp40) member C27*ENSMUSG0000002065726


Protein motifs (from Interpro)
Interpro ID Name
 IPR001806  Small GTPase superfamily
 IPR005225  Small GTP-binding protein domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007032 endosome organization IDA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0019882 antigen processing and presentation ISO
 biological_processGO:0030100 regulation of endocytosis IDA
 biological_processGO:0048227 plasma membrane to endosome transport ISO
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005769 early endosome IBA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030139 endocytic vesicle IDA
 cellular_componentGO:0031901 early endosome membrane IEA
 cellular_componentGO:0042470 melanosome IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 cellular_componentGO:0070062 extracellular exosome IEA
 cellular_componentGO:0098993 anchored component of synaptic vesicle membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005525 GTP binding IEA
 molecular_functionGO:0019003 GDP binding ISO
 molecular_functionGO:0030742 GTP-dependent protein binding IEA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation
Clathrin-mediated endocytosis
RAB geranylgeranylation
RAB GEFs exchange GTP for GDP on RABs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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