Manteia

ENSMUSG00000031504

Mus musculus

Features

Gene ID:	ENSMUSG00000031504

Biological name :	Rab20

Synonyms :	P35295 / Rab20 / Ras-related protein Rab-20

Possible biological names infered from orthology :	Q9NX57 / RAB20, member RAS oncogene family

Species:	Mus musculus

Chr. number:	8
Strand:	-1
Band:	A1.1
Gene start:	11453518
Gene end:	11478710

Corresponding Affymetrix probe sets:	10577025 (MoGene1.0st) 1438097_at (Mouse Genome 430 2.0 Array)

Cross references:	Ensembl peptide - ENSMUSP00000033900 NCBI entrez gene - 19332 See in Manteia. MGI - MGI:102789 RefSeq - NM_011227 RefSeq Peptide - NP_035357 swissprot - P35295 swissprot - Q3TPA7 Ensembl - ENSMUSG00000031504

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
Rab5b / P61021 / RAB5B, member RAS oncogene family / P61020*	ENSMUSG00000000711	28
Rab5a / Q9CQD1 / Ras-related protein Rab-5A / P20339* / RAB5A, member RAS oncogene family*	ENSMUSG00000017831	28
Rab17 / P35292 / Ras-related protein Rab-17 / Q9H0T7* / RAB17, member RAS oncogene family*	ENSMUSG00000026304	27
Rab5c / P35278 / RAB5C, member RAS oncogene family / P51148*	ENSMUSG00000019173	27
Rab21 / P35282 / RAB21, member RAS oncogene family / Q9UL25*	ENSMUSG00000020132	27
P35285 / Rab22a / RAB22A, member RAS oncogene family / Q9UL26*	ENSMUSG00000027519	26
Rab31 / RAB31, member RAS oncogene family / Q13636*	ENSMUSG00000056515	25
Q8CFP6 / Dnajc27 / DnaJ homolog subfamily C member 27 / Q9NZQ0* / DnaJ heat shock protein family (Hsp40) member C27*	ENSMUSG00000020657	18

Protein motifs (from Interpro)

Interpro ID	Name
IPR001806	Small GTPase superfamily
IPR005225	Small GTP-binding protein domain
IPR027417	P-loop containing nucleoside triphosphate hydrolase

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0015031	protein transport	IEA
biological_process	GO:0030100	regulation of endocytosis	IBA
biological_process	GO:0071346	cellular response to interferon-gamma	IDA
biological_process	GO:0090383	phagosome acidification	IEA
biological_process	GO:0090385	phagosome-lysosome fusion	IEA
cellular_component	GO:0005769	early endosome	IBA
cellular_component	GO:0005794	Golgi apparatus	ISO
cellular_component	GO:0005886	plasma membrane	IBA
cellular_component	GO:0016020	membrane	IEA
cellular_component	GO:0030139	endocytic vesicle	IBA
cellular_component	GO:0030670	phagocytic vesicle membrane	IEA
cellular_component	GO:0031410	cytoplasmic vesicle	IEA
cellular_component	GO:0043231	intracellular membrane-bounded organelle	IEA
cellular_component	GO:0045335	phagocytic vesicle	ISS
molecular_function	GO:0000166	nucleotide binding	IEA
molecular_function	GO:0003924	GTPase activity	IEA
molecular_function	GO:0005525	GTP binding	IEA

Pathways (from Reactome)

Pathway description

RAB geranylgeranylation

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
MP:0002451	abnormal macrophage physiology	"abnormal function or response of the phagocytic leukocytes involved in innate immunity, early non-adaptive phases of host-defense, antigen presentation, and which act as effector cells in humoral and cell-mediated immunity" [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Fabp4^tm1Brsp/Fabp4^tm1Brsp,Fabp5^tm1Hota/Fabp5^tm1Hota Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J * SJL

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

External programs and data are copyrighted by and are the property of their respective authors. The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation
		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr