ENSMUSG00000001521


Mus musculus

Features
Gene ID: ENSMUSG00000001521
  
Biological name :Tulp3
  
Synonyms : O88413 / tubby-like protein 3 / Tulp3
  
Possible biological names infered from orthology : O75386
  
Species: Mus musculus
  
Chr. number: 6
Strand: -1
Band: F3
Gene start: 128321161
Gene end: 128355851
  
Corresponding Affymetrix probe sets: 10548163 (MoGene1.0st)   1418251_at (Mouse Genome 430 2.0 Array)   1449008_at (Mouse Genome 430 2.0 Array)   1453082_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000001562
Ensembl peptide - ENSMUSP00000145361
Ensembl peptide - ENSMUSP00000145180
NCBI entrez gene - 22158     See in Manteia.
MGI - MGI:1329045
RefSeq - NM_011657
RefSeq - XM_006505909
RefSeq Peptide - NP_035787
swissprot - A0A0N4SW40
swissprot - O88413
swissprot - A0A0N4SVN5
Ensembl - ENSMUSG00000001521
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 zmp:0000000711ENSDARG00000063672Danio rerio
 TULP3ENSGALG00000013424Gallus gallus
 TULP3ENSG00000078246Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Tub / P50586 / tubby bipartite transcription factor / P50607*ENSMUSG0000003102860
Tulp1 / Q9Z273 / tubby like protein 1 / O00294*ENSMUSG0000003744646
Tulp2 / P46686 / tubby-like protein 2 / O00295*ENSMUSG0000002346744
Tulp4 / Q9JIL5 / tubby like protein 4 / Q9NRJ4*ENSMUSG0000003437727
Wdr35 / Q8BND3 / WD repeat domain 35 / Q9P2L0*ENSMUSG0000006664320


Protein motifs (from Interpro)
Interpro ID Name
 IPR000007  Tubby, C-terminal
 IPR005398  Tubby, N-terminal
 IPR018066  Tubby, C-terminal, conserved site
 IPR025659  Tubby-like, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001841 neural tube formation IMP
 biological_processGO:0001843 neural tube closure IMP
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007420 brain development IMP
 biological_processGO:0008277 regulation of G-protein coupled receptor protein signaling pathway IEA
 biological_processGO:0008589 regulation of smoothened signaling pathway IMP
 biological_processGO:0009952 anterior/posterior pattern specification IMP
 biological_processGO:0021904 dorsal/ventral neural tube patterning IMP
 biological_processGO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning IMP
 biological_processGO:0021915 neural tube development IMP
 biological_processGO:0021953 central nervous system neuron differentiation IMP
 biological_processGO:0031076 embryonic camera-type eye development IMP
 biological_processGO:0042733 embryonic digit morphogenesis IMP
 biological_processGO:0045879 negative regulation of smoothened signaling pathway IEA
 biological_processGO:0048702 embryonic neurocranium morphogenesis IMP
 biological_processGO:0060173 limb development IMP
 biological_processGO:0060348 bone development IMP
 biological_processGO:0060434 bronchus morphogenesis IMP
 biological_processGO:0060831 smoothened signaling pathway involved in dorsal/ventral neural tube patterning IMP
 biological_processGO:0061548 ganglion development IMP
 biological_processGO:0097500 receptor localization to non-motile cilium IBA
 biological_processGO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning IMP
 biological_processGO:1903546 protein localization to photoreceptor outer segment IBA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0005929 cilium ISO
 cellular_componentGO:0005930 axoneme IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030991 intraciliary transport particle A IEA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0097546 ciliary base IEA
 molecular_functionGO:0019899 enzyme binding IEA
 molecular_functionGO:0035091 phosphatidylinositol binding IEA
 molecular_functionGO:0044877 protein-containing complex binding IEA


Pathways (from Reactome)
Pathway description
Hedgehog off state


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000137 abnormal vertebrae morphology "malformed bony segment of the spinal column" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Zeb1Tw/Zeb1Tw
Genetic Background: Not Specified

 MP:0000153 rib bifurcation "forking or division of ribs, may be a result of partial rib fusions" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Tulp3hhkr/Tulp3hhkr
Genetic Background: involves: C3H/HeH * C57BL/6

 MP:0000432 abnormal head morphology "anomalous structure or development of the portion of the body containing the brain and organs of sight, hearing, taste, and smell " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Tulp3hhkr/Tulp3hhkr
Genetic Background: involves: C3H/HeH * C57BL/6

 MP:0000562 polydactyly "greater than 5 digits on one or more autopods" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Tulp3hhkr/Tulp3hhkr
Genetic Background: involves: C3H/HeH * C57BL/6

Allelic Composition: Gli3Xt-J/Gli3+,Tulp3hhkr/Tulp3+
Genetic Background: involves: C3H/HeH * C3H/HeJ * C57BL/6

Allelic Composition: Gli3Xt-J/Gli3+,Tulp3hhkr/Tulp3hhkr
Genetic Background: involves: C3H/HeH * C3H/HeJ * C57BL/6

 MP:0000565 oligodactyly "congenital condition in which some digits or parts of digits are missing" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:53370]
Show

Allelic Composition: Shhtm1Chg/Shhtm1Chg,Tulp3hhkr/Tulp3hhkr
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C3H/HeH * C57BL/6

 MP:0000783 abnormal forebrain morphology "malformed or absent anterior primitive cerebral vesicle; most rostral of three primary vesicles of the embryonic neural tube" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:38857]
Show

Allelic Composition: Tulp3tm1Jng/Tulp3+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

 MP:0000784 forebrain hypoplasia "reduced cell number in the anterior primitive cerebral vesicle; most rostral of three primary vesicles of the embryonic neural tube" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Tulp3tm1Jng/Tulp3+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

 MP:0000841 abnormal hindbrain morphology "malformed caudal region of the brain; includes cerebellum, pons and medulla oblongata" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:45302]
Show

Allelic Composition: Zeb1Tw/Zeb1Tw
Genetic Background: Not Specified

Allelic Composition: Tulp3tm1Jng/Tulp3+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

 MP:0000897 abnormal midbrain "malformation or malfunction associated with the middle of the three cerebral vesicles of the embryo; this region controls sensory and motor functions, including eye movement and coordination of auditory and visual reflexes" [J:23882, Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]
Show

Allelic Composition: Zeb1Tw/Zeb1Tw
Genetic Background: Not Specified

Allelic Composition: Tulp3tm1Jng/Tulp3+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

 MP:0000913 abnormal brain development "malformed or incomplete differentiation of the brain" [MGI:cls, J:49840]
Show

Allelic Composition: Zeb1Tw/Zeb1Tw
Genetic Background: Not Specified

 MP:0000914 exencephaly "neurocranial defects resulting in exposure or extrusion of the brain" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840]
Show

Allelic Composition: Zeb1Tw/Zeb1Tw
Genetic Background: Not Specified

Allelic Composition: Tulp3hhkr/Tulp3hhkr
Genetic Background: involves: C3H/HeH * C57BL/6

Allelic Composition: Tulp3hhkr/Tulp3tm1Jng
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C3H/HeH * C57BL/6

Allelic Composition: Shhtm1Chg/Shhtm1Chg,Tulp3hhkr/Tulp3hhkr
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C3H/HeH * C57BL/6

 MP:0000928 incomplete cephalic closure "arrest of the fusion of the cephalic neural folds" [J:12622]
Show

Allelic Composition: Tulp3hhkr/Tulp3hhkr
Genetic Background: involves: C3H/HeH * C57BL/6

 MP:0000929 open neural tube "incomplete invagination and fusion of the neuroepithelial layer in early development" [MGI:CLS, J:53370, J:62571]
Show

Allelic Composition: Zeb1Tw/Zeb1Tw
Genetic Background: Not Specified

Allelic Composition: Tulp3tm1Jng/Tulp3+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

 MP:0000961 abnormal dorsal root ganglia morphology "malformed group of nerve cell bodies of each segmental nerve projecting from the spinal cord " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:60159]
Show

Allelic Composition: Zeb1Tw/Zeb1Tw
Genetic Background: Not Specified

 MP:0001286 abnormal eye development "malformation or arrest of differentiation of the visual organ" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:49840]
Show

Allelic Composition: Tulp3hhkr/Tulp3hhkr
Genetic Background: involves: C3H/HeH * C57BL/6

 MP:0001577 anemia "less than normal levels of red blood cells, hemoglobin or volume of packed red blood cells " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:53370]
Show

Allelic Composition: Zeb1Tw/Zeb1Tw
Genetic Background: Not Specified

 MP:0001634 internal hemorrhage "blood loss in the interior of the body due to vessel rupture or dysmorphology " [J:23170]
Show

Allelic Composition: Zeb1Tw/Zeb1Tw
Genetic Background: Not Specified

 MP:0001785 edema "an accumulation of an excessive amount of watery fluid in cells or intercellular tissues" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:54065]
Show

Allelic Composition: Tulp3hhkr/Tulp3hhkr
Genetic Background: involves: C3H/HeH * C57BL/6

Allelic Composition: Tulp3hhkr/Tulp3tm1Jng
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C3H/HeH * C57BL/6

Allelic Composition: Shhtm1Chg/Shhtm1Chg,Tulp3hhkr/Tulp3hhkr
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C3H/HeH * C57BL/6

 MP:0001787 pericardial edema "accumulation of watery fluid in the pericardial sac of the heart" [J:52597]
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Allelic Composition: Smotm1Amc/Smotm1Amc,Tulp3hhkr/Tulp3hhkr
Genetic Background: involves: 129X1/SvJ * C3H/HeH * C57BL/6

 MP:0001914 hemorrhage "loss of blood from the vascular compartment to the exterior or into nonvascular body space as a result of rupture or severance of the blood vessels" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Tulp3tm1Jng/Tulp3+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

 MP:0001915 intracranial hemorrhage "bleeding within the skull, including hemorrhage into the brain and within the cranial epidural, subdural, and subarachnoid spaces" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Zeb1Tw/Zeb1Tw
Genetic Background: Not Specified

 MP:0002110 abnormal digit morphology "abnormal development of the digits resulting in structural abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: EdaTa-J/Eda+
Genetic Background: 129/Sv

 MP:0002151 abnormal neural tube morphology/development "anomalous structure of or development of the embryonic neural tube resulting in structural anomaly" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Zeb1Tw/Zeb1Tw
Genetic Background: Not Specified

Allelic Composition: Tulp3hhkr/Tulp3hhkr
Genetic Background: involves: C3H/HeH * C57BL/6

Allelic Composition: Shhtm1Chg/Shhtm1Chg,Tulp3hhkr/Tulp3hhkr
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C3H/HeH * C57BL/6

Allelic Composition: Smotm1Amc/Smotm1Amc,Tulp3hhkr/Tulp3hhkr
Genetic Background: involves: 129X1/SvJ * C3H/HeH * C57BL/6

 MP:0002152 abnormal brain morphology "anomalous structure of or abnormal development of the brain, one of the two components of the central nervous system and the center of thought and emotion; controls coordination, bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.)" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, http://cancerweb.ncl.ac.uk]
Show

Allelic Composition: Zeb1Tw/Zeb1Tw
Genetic Background: Not Specified

 MP:0002809 enlarged spinal cord size "larger appearance of the spinal cord" [J:83935]
Show

Allelic Composition: Smotm1Amc/Smotm1Amc,Tulp3hhkr/Tulp3hhkr
Genetic Background: involves: 129X1/SvJ * C3H/HeH * C57BL/6

 MP:0002948 abnormal neuronal specification "defects in the developmental patterning of neurons resulting in ectopic placement, decreased numbers or absence of mature neurons" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:87948]
Show

Allelic Composition: Zeb1Tw/Zeb1Tw
Genetic Background: Not Specified

 MP:0003054 spina bifida "common congenital midline defect of fusion of the vertebral arch" [MeSH:National Library of Medicine - Medical Subject Headings, 2003]
Show

Allelic Composition: Zeb1Tw/Zeb1Tw
Genetic Background: Not Specified

Allelic Composition: Tulp3hhkr/Tulp3tm1Jng
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C3H/HeH * C57BL/6

Allelic Composition: Shhtm1Chg/Shhtm1Chg,Tulp3hhkr/Tulp3hhkr
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C3H/HeH * C57BL/6

 MP:0003717 pallor "an unnatural paleness to the skin, generally attributable to anemia" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Zeb1Tw/Zeb1Tw
Genetic Background: Not Specified

 MP:0003861 abnormal nervous system development "impaired or altered growth of the components of the nervous system" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Tulp3hhkr/Tulp3hhkr
Genetic Background: involves: C3H/HeH * C57BL/6

 MP:0003935 abnormal craniofacial development "anomaly in the process of forming the face and/or cranium" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Zeb1Tw/Zeb1Tw
Genetic Background: Not Specified

 MP:0003961 decreased lean body mass "less than average fat-free physical bulk or volume of the body including all its components except adipose tissue" [honda:Hiraoki Onda, Mouse GEnome Informatics Curator]
Show

Allelic Composition: Tmod2tm1b(KOMP)Wtsi/Tmod2tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Tmod2tm1b(KOMP)Wtsi/J

 MP:0004083 polysyndactyly "greater than 5 digits present on an autopod with interdigital webbing also present" [rbabiuk:Randall Babiuk, Mouse Genome Informatics Curator]
Show

Allelic Composition: Gli3Xt-J/Gli3Xt-J,Tulp3hhkr/Tulp3+
Genetic Background: involves: C3H/HeH * C3H/HeJ * C57BL/6

 MP:0005225 abnormal vertebrae development "anomalous formation of the vertebrae from the sclerotome" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Tulp3hhkr/Tulp3hhkr
Genetic Background: involves: C3H/HeH * C57BL/6

 MP:0005293 impaired glucose tolerance "less than the normal response to oral consumption or intravenous injection of specified amounts of glucose and indicative of insulin resistance; measured by determining whole blood or plasma sugar level in a fasting state before and after taking glucose at specified intervals" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Tmod2tm1b(KOMP)Wtsi/Tmod2tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Tmod2tm1b(KOMP)Wtsi/J

 MP:0005297 spina bifida occulta "common congenital midline defect of fusion of the vertebral arch without protrusion of the spinal cord or meninges" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Tulp3hhkr/Tulp3hhkr
Genetic Background: involves: C3H/HeH * C57BL/6

 MP:0005343 increased circulating aspartate transaminase level "greater than normal concentration in the blood of this enzyme, which catalyzes the reversible transfer of an amine group from l-glutamic acid to oxaloacetic acid, forming alpha-ketoglutaric acid and l-aspartic acid; aids in diagnosis of viral hepatitis and myocardial infarction" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:85204]
Show

Allelic Composition: Tmod2tm1b(KOMP)Wtsi/Tmod2tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Tmod2tm1b(KOMP)Wtsi/J

 MP:0006042 increased apoptosis "greater than normal programmed cell death" [RGD:Rat Genome Database submission, smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Zeb1Tw/Zeb1Tw
Genetic Background: Not Specified

 MP:0006108 abnormal hindbrain development "anomaly in the formation or pattering of the caudal region of the brain" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:93573]
Show

Allelic Composition: Zeb1Tw/Zeb1Tw
Genetic Background: Not Specified

 MP:0006253 clinodactyly "abnormal lateral curvature of one or more digits towards or away from each other" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:98519]
Show

Allelic Composition: Tulp3hhkr/Tulp3hhkr
Genetic Background: involves: C3H/HeH * C57BL/6

 MP:0008797 facial cleft "a cleft resulting from incomplete merging or fusion of any of the embryonic facial processes that normally unite to form the face" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Zeb1Tw/Zeb1Tw
Genetic Background: Not Specified

 MP:0009142 decreased prepulse inhibition "decrease in the ability of a relatively mild stimulus to suppress the response to a strong, startle-eliciting stimulus" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Tmod2tm1b(KOMP)Wtsi/Tmod2tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Tmod2tm1b(KOMP)Wtsi/J

 MP:0010024 increased total body fat amount "greater than the normal total amount of connective tissue composed of fat cells within the entire body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Tmod2tm1b(KOMP)Wtsi/Tmod2tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Tmod2tm1b(KOMP)Wtsi/J

 MP:0011099 complete lethality throughout fetal growth and development "death of all organisms of a given genotype in a population between the completion of organogenesis and birth (Mus: E14 to approximately E18.5)" [MGI:csmith]
Show

Allelic Composition: Zeb1Tw/Zeb1Tw
Genetic Background: Not Specified

Allelic Composition: Gli3Xt-J/Gli3Xt-J,Tulp3hhkr/Tulp3hhkr
Genetic Background: involves: C3H/HeH * C3H/HeJ * C57BL/6

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Tmod2tm1b(KOMP)Wtsi/Tmod2tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Tmod2tm1b(KOMP)Wtsi/J

 MP:0011102 partial embryonic lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the embryonic period prior to organogenesis (Mus: prior to E14)" [MGI:csmith]
Show

Allelic Composition: Tulp3tm1Jng/Tulp3+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

 MP:0012544 abnormal caudal neuropore morphology "any structural anomaly of the temporary opening at the extreme caudal end of the neural tube in early embryos; the posterior neuropore appears before the process of neural tube closure is complete" [MGI:anna]
Show

Allelic Composition: Tulp3hhkr/Tulp3hhkr
Genetic Background: involves: C3H/HeH * C57BL/6

 MP:0012547 spina bifida cystica "spinal bifida in which a hernial cyst containing meninges (meningocele), spinal cord (myelocele), or both (myelomeningocele) protrudes through a congenital cleft in the vertebral column; the protruding sac is encased in a layer of skin or a fine membrane that readily ruptures, causing leakage of cerebrospinal fluid and an increased risk of meningeal infection" [MGI:anna]
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Allelic Composition: Tulp3hhkr/Tulp3hhkr
Genetic Background: involves: C3H/HeH * C57BL/6

 MP:0012701 increased embryonic neuroepithelium apoptosis "increase in the number of cells of the embryonic neuroepithelium undergoing programmed cell death" [MGI:anna]
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Allelic Composition: Zeb1Tw/Zeb1Tw
Genetic Background: Not Specified

Allelic Composition: Tulp3tm1Jng/Tulp3+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

 MP:0012703 decreased embryonic neuroepithelium thickness "reduced width of the epithelial cell layer that lines the neural tube and develops into the nervous system and into the neural crest cells" [MGI:anna]
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Allelic Composition: Tulp3hhkr/Tulp3hhkr
Genetic Background: involves: C3H/HeH * C57BL/6

 MP:0012707 incomplete caudal neuropore closure "incomplete joining together of the neural folds of the caudal opening of the neural tube; failure of caudal neuropore closure results in spina bifida, the severity of which depends on how much of the spinal cord remains exposed" [MGI:anna]
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Allelic Composition: Tulp3hhkr/Tulp3hhkr
Genetic Background: involves: C3H/HeH * C57BL/6

 MP:0013278 decreased fasted circulating glucose level "reduction in the amount of glucose in the blood at some defined time point after eating compared to controls" [MGI:Armida_Di_Fenza]
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Allelic Composition: Tmod2tm1b(KOMP)Wtsi/Tmod2tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Tmod2tm1b(KOMP)Wtsi/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000040836 B2RPY5 / Gpr161 / G protein-coupled receptor 161 / Q8N6U8*  / reaction / complex
 ENSMUSG00000024169 E9PY46 / Ift140 / Intraflagellar transport / Q96RY7* / intraflagellar transport 140*  / reaction / complex
 ENSMUSG00000030323 Ift122 / Q6NWV3 / Intraflagellar transport / Q9HBG6* / intraflagellar transport 122*  / complex / reaction
 ENSMUSG00000037890 Wdr19 / Q3UGF1 / WD repeat domain 19 / Q8NEZ3*  / reaction / complex
 ENSMUSG00000066643 Wdr35 / Q8BND3 / WD repeat domain 35 / Q9P2L0*  / reaction / complex
 ENSMUSG00000034848 Q0HA38 / Ttc21b / tetratricopeptide repeat domain 21B / Q7Z4L5*  / reaction / complex






 

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