| MP:0000088 | short mandible | "reduced length of the lower bony framework of the mouth where the inferior teeth are held" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Gfi1btm1Tmo/Gfi1btm1Tmo
Genetic Background: B6.129-Gfi1btm1Tmo
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| MP:0000120 | malocclusion | "perturbations in the normal patterned arrangement of the teeth or alignment of the jaw, resulting in the incorrect position of biting or chewing surfaces of the upper and lower teeth" [J:61509] |
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Allelic Composition: Gfi1btm1Tmo/Gfi1btm1Tmo
Genetic Background: B6.129-Gfi1btm1Tmo
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| MP:0000186 | decreased circulating HDL cholesterol level | "lower than average level of high density lipoprotein in blood; this molecule transports cholesterol to the liver for excretion in bile" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Robo2tm1Rilm/Robo2tm1Rilm,Olfr160tm4Mom/?,Omptm1(cre)Jae/Omp+
Genetic Background: involves: 129 * 129P2/OlaHsd * 129S1/Sv
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| MP:0000194 | hypercalcemia | "abnormally high concentration of calcium ions in the circulating blood " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Baz1btm1Ska/Baz1b+
Genetic Background: involves: C57BL/6 * CBA
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| MP:0000266 | abnormal cardiac morphology | "anomalies in the hollow, muscular organ that maintains the circulation of the blood" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Nlrp3tm1Wstr/Nlrp3+
Genetic Background: involves: C57BL/6
Allelic Composition: Baz1btm1Ska/Baz1b+
Genetic Background: involves: C57BL/6 * CBA
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| MP:0000284 | double outlet right ventricle | "both the aorta and the pulmonary trunk originate from the right ventricle, usually in conjunction with a ventricular septal defect" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:67826] |
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Allelic Composition: Nlrp3tm1Wstr/Nlrp3+
Genetic Background: involves: C57BL/6
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| MP:0000445 | short snout | "reduced length of the anterior facial part of the muzzle" [J:53370] |
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Allelic Composition: Gfi1btm1Tmo/Gfi1btm1Tmo
Genetic Background: B6.129-Gfi1btm1Tmo
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| MP:0000460 | mandible hypoplasia | "arrested growth or atrophy of the lower bony framework of the mouth where the inferior teeth are held" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, tc:Teresa Chu , Mouse Genome Informatics Curator, J:54637] |
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Allelic Composition: Gfi1btm1Tmo/Gfi1btm1Tmo
Genetic Background: B6.129-Gfi1btm1Tmo
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| MP:0001262 | decreased body weight | "lower than normal average weight " [J:61295] |
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Allelic Composition: Robo2tm1Rilm/Robo2tm1Rilm,Olfr160tm4Mom/?,Omptm1(cre)Jae/Omp+
Genetic Background: involves: 129 * 129P2/OlaHsd * 129S1/Sv
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| MP:0001265 | reduced body size | "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170] |
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Allelic Composition: Gfi1btm1Tmo/Gfi1btm1Tmo
Genetic Background: B6.129-Gfi1btm1Tmo
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| MP:0001935 | reduced litter size | "fewer live born pups in a litter compared to average" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Gfi1btm1Tmo/Gfi1btm1Tmo
Genetic Background: B6.129-Gfi1btm1Tmo
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| MP:0002082 | postnatal lethality | "premature death anytime after postnatal day 1 to weaning age (3 weeks)" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Gfi1btm1Tmo/Gfi1btm1Tmo
Genetic Background: B6.129-Gfi1btm1Tmo
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| MP:0002189 | abnormal myocardial trabeculae morphology | "malformation of the supporting bundles of muscular fibers lining the walls of the heart" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Nlrp3tm1Wstr/Nlrp3+
Genetic Background: involves: C57BL/6
Allelic Composition: Baz1btm1Ska/Baz1b+
Genetic Background: involves: C57BL/6 * CBA
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| MP:0002753 | dilated left ventricle | "an expansion in the volume of the lower left chamber of the heart" [J:82859, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
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Allelic Composition: Nlrp3tm1Wstr/Nlrp3+
Genetic Background: involves: C57BL/6
Allelic Composition: Baz1btm1Ska/Baz1b+
Genetic Background: involves: C57BL/6 * CBA
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| MP:0002754 | dilated right ventricle | "an expansion in the volume of the lower right chamber of the heart" [J:82859, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
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Allelic Composition: Nlrp3tm1Wstr/Nlrp3+
Genetic Background: involves: C57BL/6
Allelic Composition: Baz1btm1Ska/Baz1b+
Genetic Background: involves: C57BL/6 * CBA
|
| MP:0003387 | coarctation of aorta | "narrowing of the aorta" [smb:Susan M Bello, Mouse Genome Informatics Curator, ncbi:Matthew Mailman, NCBI request] |
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Allelic Composition: Nlrp3tm1Wstr/Nlrp3+
Genetic Background: involves: C57BL/6
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| MP:0004200 | reduced fetal size | "smaller proportions of a fetus compared to littermates (sensu Mus: from E14 through birth)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Gfi1btm1Tmo/Gfi1btm1Tmo
Genetic Background: B6.129-Gfi1btm1Tmo
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| MP:0004418 | small parietal bone | "reduced size of the curved bone forming part of the vault of the cranium" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Gfi1btm1Tmo/Gfi1btm1Tmo
Genetic Background: B6.129-Gfi1btm1Tmo
Allelic Composition: Baz1bMommeD10/Baz1b+
Genetic Background: involves: FVB/N
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| MP:0004471 | short nasal bone | "reduced length of either of two rectangular bone plates forming the bridge of the nose" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Gfi1btm1Tmo/Gfi1btm1Tmo
Genetic Background: B6.129-Gfi1btm1Tmo
Allelic Composition: Baz1bMommeD10/Baz1b+
Genetic Background: involves: FVB/N
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| MP:0005179 | decreased total circulating cholesterol level | "less than the normal concentration in the blood of these most abundant steroids in animal tissues, and precursors to steroid hormones and bile salts; also components of plasma membranes" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Robo2tm1Rilm/Robo2tm1Rilm,Olfr160tm4Mom/?,Omptm1(cre)Jae/Omp+
Genetic Background: involves: 129 * 129P2/OlaHsd * 129S1/Sv
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| MP:0005249 | abnormal palatine bone morphology | "structural anomaly of the anteriorly located rigid section of the palate" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Gfi1btm1Tmo/Gfi1btm1Tmo
Genetic Background: B6.129-Gfi1btm1Tmo
Allelic Composition: Baz1bMommeD10/Baz1b+
Genetic Background: involves: FVB/N
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| MP:0005329 | abnormal cardiac muscle morphology | "anomalous structure of the involuntary muscle comprising the myocardium " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
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Allelic Composition: Nlrp3tm1Wstr/Nlrp3+
Genetic Background: involves: C57BL/6
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| MP:0005560 | decreased circulating glucose level | "less than the normal concentration in the blood of this major monosaccharide of the body; it is an important energy source" [RGD:Rat Genome Database submission, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Robo2tm1Rilm/Robo2tm1Rilm,Olfr160tm4Mom/?,Omptm1(cre)Jae/Omp+
Genetic Background: involves: 129 * 129P2/OlaHsd * 129S1/Sv
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| MP:0005567 | decreased circulating total protein level | "less than the average total concentration of these macromolecules in the blood " [RGD:Rat Genome Database submission] |
Show
Allelic Composition: Robo2tm1Rilm/Robo2tm1Rilm,Olfr160tm4Mom/?,Omptm1(cre)Jae/Omp+
Genetic Background: involves: 129 * 129P2/OlaHsd * 129S1/Sv
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| MP:0006411 | upturned snout | "muzzle has a curve or tilt such that the tip points upwards" [MGI:brs "Beverly Richards-Smith, Mouse Genome Informatics Curator", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Gfi1btm1Tmo/Gfi1btm1Tmo
Genetic Background: B6.129-Gfi1btm1Tmo
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| MP:0009703 | decreased birth body size | "reduction in average body size at birth compared to controls" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Nlrp3tm1Wstr/Nlrp3+
Genetic Background: involves: C57BL/6
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| MP:0010403 | atrial septal defect | "abnormal communications between the two upper chambers of the heart, including such defects in any or all of the ostium primum, ostium secundum, sinus venosus, and coronary sinus regions" [MESH:C14.240.400.560.375] |
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Allelic Composition: Nlrp3tm1Wstr/Nlrp3+
Genetic Background: involves: C57BL/6
Allelic Composition: Baz1btm1Ska/Baz1b+
Genetic Background: involves: C57BL/6 * CBA
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| MP:0010420 | muscular ventricular septal defect | "abnormal communications between the two lower chambers of the heart, involving the muscular septum and often occurring as multiple communications, and includes central muscular or midmuscular, apical, or marginal communications when the defect is along the RV-septal junction; any single defect observed from the LV aspect may have several openings on the RV aspect" [http://emedicine.medscape.com] |
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Allelic Composition: Nlrp3tm1Wstr/Nlrp3+
Genetic Background: involves: C57BL/6
Allelic Composition: Baz1btm1Ska/Baz1b+
Genetic Background: involves: C57BL/6 * CBA
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| MP:0010563 | increased heart right ventricle size | "greater than average size of the right ventricle" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Nlrp3tm1Wstr/Nlrp3+
Genetic Background: involves: C57BL/6
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| MP:0010579 | increased heart left ventricle size | "greater than average size of the left ventricle" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Nlrp3tm1Wstr/Nlrp3+
Genetic Background: involves: C57BL/6
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| MP:0010948 | abnormal double-strand DNA break repair | "any annomaly in the process of repair of double-strand breaks in DNA via homologous and nonhomologous mechanisms to reform a continuous DNA helix" [GO:0006302] |
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Allelic Composition: Nlrp3tm1Wstr/Nlrp3+
Genetic Background: involves: C57BL/6
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| MP:0011085 | complete postnatal lethality | "premature death anytime between the neonatal period and weaning age of all organisms of a given genotype in a population (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith] |
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Allelic Composition: Nlrp3tm1Wstr/Nlrp3+
Genetic Background: involves: C57BL/6
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| MP:0013270 | fourth pharyngeal arch hypoplasia | "underdevelopment or reduced size of the fourth pharyngeal arch, usually due to reduced cell number" [MGI:anna] |
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Allelic Composition: Nlrp3tm1Wstr/Nlrp3+
Genetic Background: involves: C57BL/6
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| MP:0030049 | prominent forehead | "forward prominence of the entire forehead, due to protrusion of the frontal bone; not to be confused with frontal bossing" [HP:0011220] |
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Allelic Composition: Gfi1btm1Tmo/Gfi1btm1Tmo
Genetic Background: B6.129-Gfi1btm1Tmo
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