ENSMUSG00000004815


Mus musculus

Features
Gene ID: ENSMUSG00000004815
  
Biological name :Dgkq
  
Synonyms : Dgkq / Diacylglycerol kinase theta / Q6P5E8
  
Possible biological names infered from orthology : P52824
  
Species: Mus musculus
  
Chr. number: 5
Strand: -1
Band: F
Gene start: 108646693
Gene end: 108669672
  
Corresponding Affymetrix probe sets: 10532216 (MoGene1.0st)   1437000_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000118466
Ensembl peptide - ENSMUSP00000122837
Ensembl peptide - ENSMUSP00000057859
Ensembl peptide - ENSMUSP00000118065
NCBI entrez gene - 110524     See in Manteia.
MGI - MGI:102918
RefSeq - XM_011249392
RefSeq - XM_011249397
RefSeq - XM_017320603
RefSeq - NM_199011
RefSeq - XM_006534726
RefSeq Peptide - NP_950176
swissprot - Q6P5E8
swissprot - D6RFT1
swissprot - D6RI30
Ensembl - ENSMUSG00000004815
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DGKQENSGALG00000002142Gallus gallus
 DGKQENSG00000145214Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Dgkb / Q6NS52 / Diacylglycerol kinase beta / Q9Y6T7*ENSMUSG0000003609523
Dgkd / diacylglycerol kinase delta / Q16760*ENSMUSG0000007073822
Dgkk / diacylglycerol kinase kappa / Q5KSL6*ENSMUSG0000006239322
Dgkh / diacylglycerol kinase eta / Q86XP1*ENSMUSG0000003473122
Dgkg / Q91WG7 / Diacylglycerol kinase gamma / P49619*ENSMUSG0000002286122
Dgkz / Q80UP3 / Diacylglycerol kinase zeta / Q13574*ENSMUSG0000004047921
Dgka / O88673 / Mus musculus diacylglycerol kinase, alpha (Dgka), transcript variant 2, mRNA. / P23743* / diacylglycerol kinase alpha*ENSMUSG0000002535721
Dgki / diacylglycerol kinase iota isoform 2 / O75912* / diacylglycerol kinase iota*ENSMUSG0000003866519
Dgke / Q9R1C6 / Diacylglycerol kinase epsilon / P52429*ENSMUSG0000000027619


Protein motifs (from Interpro)
Interpro ID Name
 IPR000159  Ras-associating (RA) domain
 IPR000756  Diacylglycerol kinase, accessory domain
 IPR001206  Diacylglycerol kinase, catalytic domain
 IPR002219  Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
 IPR016064  NAD kinase/diacylglycerol kinase-like domain superfamily
 IPR017438  Inorganic polyphosphate/ATP-NAD kinase, N-terminal
 IPR020454  Diacylglycerol/phorbol-ester binding
 IPR029071  Ubiquitin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006111 regulation of gluconeogenesis IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006654 phosphatidic acid biosynthetic process IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007171 activation of transmembrane receptor protein tyrosine kinase activity IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0008277 regulation of G-protein coupled receptor protein signaling pathway IEA
 biological_processGO:0010628 positive regulation of gene expression IEA
 biological_processGO:0010629 negative regulation of gene expression IEA
 biological_processGO:0010801 negative regulation of peptidyl-threonine phosphorylation IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018105 peptidyl-serine phosphorylation IEA
 biological_processGO:0019933 cAMP-mediated signaling IEA
 biological_processGO:0033198 response to ATP IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0046339 diacylglycerol metabolic process IEA
 biological_processGO:0046486 glycerolipid metabolic process IEA
 biological_processGO:0046834 lipid phosphorylation IEA
 biological_processGO:0050731 positive regulation of peptidyl-tyrosine phosphorylation IEA
 biological_processGO:0051591 response to cAMP IEA
 biological_processGO:0070493 thrombin-activated receptor signaling pathway IEA
 biological_processGO:0070528 protein kinase C signaling IEA
 biological_processGO:0090181 regulation of cholesterol metabolic process IEA
 biological_processGO:1903432 regulation of TORC1 signaling IEA
 biological_processGO:2000064 regulation of cortisol biosynthetic process IEA
 biological_processGO:2000182 regulation of progesterone biosynthetic process IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005856 cytoskeleton ISO
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0012506 vesicle membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016363 nuclear matrix IEA
 cellular_componentGO:0016607 nuclear speck ISO
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003951 NAD+ kinase activity IEA
 molecular_functionGO:0004143 diacylglycerol kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0019900 kinase binding IEA
 molecular_functionGO:0030297 transmembrane receptor protein tyrosine kinase activator activity IEA
 molecular_functionGO:0033613 activating transcription factor binding IEA
 molecular_functionGO:0043274 phospholipase binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Effects of PIP2 hydrolysis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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