ENSMUSG00000034731


Mus musculus

Features
Gene ID: ENSMUSG00000034731
  
Biological name :Dgkh
  
Synonyms : Dgkh / diacylglycerol kinase eta
  
Possible biological names infered from orthology : Q86XP1
  
Species: Mus musculus
  
Chr. number: 14
Strand: -1
Band: D3
Gene start: 78558750
Gene end: 78732776
  
Corresponding Affymetrix probe sets: 10421774 (MoGene1.0st)   1438310_at (Mouse Genome 430 2.0 Array)   1457213_a_at (Mouse Genome 430 2.0 Array)   1459906_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000074290
Ensembl peptide - ENSMUSP00000154036
Ensembl peptide - ENSMUSP00000154107
Ensembl peptide - ENSMUSP00000154554
Ensembl peptide - ENSMUSP00000154031
NCBI entrez gene - 380921     See in Manteia.
MGI - MGI:2444188
RefSeq - XM_011245103
RefSeq - XM_006519173
RefSeq - XM_011245099
RefSeq - XM_011245100
RefSeq - XM_011245101
RefSeq - XM_011245102
RefSeq - NM_001081336
RefSeq - NM_001253766
RefSeq - NM_001281794
RefSeq - XM_006519169
RefSeq - XM_006519171
RefSeq - XM_006519172
RefSeq Peptide - NP_001240695
RefSeq Peptide - NP_001268723
RefSeq Peptide - NP_001074805
swissprot - D3YXJ0
swissprot - A0JP53
Ensembl - ENSMUSG00000034731
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dgkhENSDARG00000018716Danio rerio
 DGKHENSGALG00000016959Gallus gallus
 DGKHENSG00000102780Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Dgkd / diacylglycerol kinase delta / Q16760*ENSMUSG0000007073864
Dgkk / diacylglycerol kinase kappa / Q5KSL6*ENSMUSG0000006239337
Dgkg / Q91WG7 / Diacylglycerol kinase gamma / P49619*ENSMUSG0000002286119
Dgki / diacylglycerol kinase iota isoform 2 / O75912* / diacylglycerol kinase iota*ENSMUSG0000003866519
Dgkz / Q80UP3 / Diacylglycerol kinase zeta / Q13574*ENSMUSG0000004047919
Dgkb / Q6NS52 / Diacylglycerol kinase beta / Q9Y6T7*ENSMUSG0000003609519
Dgka / O88673 / Mus musculus diacylglycerol kinase, alpha (Dgka), transcript variant 2, mRNA. / P23743* / diacylglycerol kinase alpha*ENSMUSG0000002535718
Dgkq / Q6P5E8 / Diacylglycerol kinase theta / P52824*ENSMUSG0000000481517
Dgke / Q9R1C6 / Diacylglycerol kinase epsilon / P52429*ENSMUSG0000000027616


Protein motifs (from Interpro)
Interpro ID Name
 IPR000756  Diacylglycerol kinase, accessory domain
 IPR001206  Diacylglycerol kinase, catalytic domain
 IPR001660  Sterile alpha motif domain
 IPR001849  Pleckstrin homology domain
 IPR002219  Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
 IPR011993  PH-like domain superfamily
 IPR013761  Sterile alpha motif/pointed domain superfamily
 IPR016064  NAD kinase/diacylglycerol kinase-like domain superfamily
 IPR017438  Inorganic polyphosphate/ATP-NAD kinase, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway ISO
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0046339 diacylglycerol metabolic process ISO
 biological_processGO:0046473 phosphatidic acid metabolic process ISO
 biological_processGO:0051259 protein complex oligomerization ISO
 cellular_componentGO:0005737 cytoplasm ISO
 cellular_componentGO:0005768 endosome ISO
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003951 NAD+ kinase activity IEA
 molecular_functionGO:0004143 diacylglycerol kinase activity ISO
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0042803 protein homodimerization activity ISO


Pathways (from Reactome)
Pathway description
Effects of PIP2 hydrolysis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr