ENSG00000102780


Homo sapiens

Features
Gene ID: ENSG00000102780
  
Biological name :DGKH
  
Synonyms : DGKH / diacylglycerol kinase eta / Q86XP1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 13
Strand: 1
Band: q14.11
Gene start: 42040036
Gene end: 42256578
  
Corresponding Affymetrix probe sets: 1553300_a_at (Human Genome U133 Plus 2.0 Array)   227415_at (Human Genome U133 Plus 2.0 Array)   235952_at (Human Genome U133 Plus 2.0 Array)   240145_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000482250
Ensembl peptide - ENSP00000445114
Ensembl peptide - ENSP00000485809
Ensembl peptide - ENSP00000486838
Ensembl peptide - ENSP00000486329
Ensembl peptide - ENSP00000261491
Ensembl peptide - ENSP00000337572
Ensembl peptide - ENSP00000368576
NCBI entrez gene - 160851     See in Manteia.
OMIM - 604071
RefSeq - NM_001204504
RefSeq - NM_001204505
RefSeq - NM_001204506
RefSeq - NM_001297429
RefSeq - NM_152910
RefSeq - NM_178009
RefSeq Peptide - NP_690874
RefSeq Peptide - NP_821077
RefSeq Peptide - NP_001191433
RefSeq Peptide - NP_001191434
RefSeq Peptide - NP_001191435
RefSeq Peptide - NP_001284358
swissprot - Q86XP1
swissprot - A0A0D9SF65
swissprot - A0A087WZ02
swissprot - A0A0D9SFR6
Ensembl - ENSG00000102780
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dgkhENSDARG00000018716Danio rerio
 DGKHENSGALG00000016959Gallus gallus
 DgkhENSMUSG00000034731Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DGKD / Q16760 / diacylglycerol kinase deltaENSG0000007704465
DGKK / Q5KSL6 / diacylglycerol kinase kappaENSG0000027458838
DGKZ / Q13574 / diacylglycerol kinase zetaENSG0000014909119
DGKI / O75912 / diacylglycerol kinase iotaENSG0000015768019
DGKG / P49619 / diacylglycerol kinase gammaENSG0000005886618
DGKA / P23743 / diacylglycerol kinase alphaENSG0000006535718
DGKB / Q9Y6T7 / diacylglycerol kinase betaENSG0000013626718
DGKQ / P52824 / diacylglycerol kinase thetaENSG0000014521416
DGKE / P52429 / diacylglycerol kinase epsilonENSG0000015393315


Protein motifs (from Interpro)
Interpro ID Name
 IPR000756  Diacylglycerol kinase, accessory domain
 IPR001206  Diacylglycerol kinase, catalytic domain
 IPR001660  Sterile alpha motif domain
 IPR001849  Pleckstrin homology domain
 IPR002219  Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
 IPR011993  PH-like domain superfamily
 IPR013761  Sterile alpha motif/pointed domain superfamily
 IPR016064  NAD kinase/diacylglycerol kinase-like domain superfamily
 IPR017438  Inorganic polyphosphate/ATP-NAD kinase, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway IMP
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0030168 platelet activation TAS
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0046473 phosphatidic acid metabolic process IDA
 biological_processGO:0051259 protein complex oligomerization IMP
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005768 endosome IDA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003951 NAD+ kinase activity IEA
 molecular_functionGO:0004143 diacylglycerol kinase activity TAS
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Effects of PIP2 hydrolysis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr